IVIG rate-related reactions include: headache (pre- and post- infusion), flu-like symptoms, fever, chills, nausea, vomiting, flushing, joint aches, blood pressure changes
and chest tightness. Patient may also exhibit discomfort at IV insertion site. If any of these symptoms occur, stop the infusion for 30 minutes, then resume at half
rate. Always titrate up to desired maximum rate, taking vital signs every 15 minutes x 1 hour, then every 30 minutes for second hour, then every hour till completion.
SoluMedrol infusion patients should be encouraged to hydrate with a flavored beverage during the infusion to mask the metallic after-taste of the drug. Repeat
patient temperature with final vital signs.