Nathalie Javidi-Sharifi, MD, PhD
Chronic Lymphocytic Leukemia in 2025: Lessons from the Past, Current Standards, and What’s Next
Learning Objectives:
1. Review the evolution of CLL treatment from chemoimmunotherapy to targeted agents (BTK and BCL2 inhibitors).
2. Apply practical principles for therapy selection and co-management of toxicities relevant to internal medicine.
3. Recognize emerging therapies (non-covalent BTKi, time-limited combinations, bispecific antibodies) and when to consider referral for clinical trials.