Xuan Qin, PhD, D(ABMM)
Title: A Plan to Insource Microbiology Service at OHSU
learning Objectives:
1.Microbiology Service at OHSU -Where we were, where we are, and where we are going?
2. Technologies – Infectious disease testing has evolved past laboratory-based microscopy, microbiological culture, and PCR. New technologies have improved the speed, efficiency, and portability of pathogen detection. These include rapid and automated antigen and antibody tests, mass spectrometry, molecular techniques, such as sequencing and automated PCR.
3. A perfect storm and a perfect opportunity – It’s the perfect time for cross sectional standards setting and to use technologies at their full potentials (STAT versus BATCH modalities?):
-To choose the right test: a test that meets the diagnostic purpose, accuracy, turn-around-time (TAT), automation, and cost.
-To confirm test performance characteristics and to develop SOPs: the basic lab process of conducting analytical validation studies for determination of test sensitivity, specificity, accuracy, and reproducibility. The SOP is developed -to minimize the variants associated with Analyte-to-Analyte, Test-to-Test, and Operator-to-Operator.
-To plan for test implementation by involving clinical stakeholders: test name, order-set, test algorithm (safety and cost-saving), report scripts, and clinical actional comments.
-To monitor test performance using quality indicators: positive rate, failure rate, turn-around-time, test utilization, critical result notification compliances …