Patient in clinic is 60F️ with 10y history of T2D. She had had “pre-diabetes” for another 10 years prior to that, & her A1c for the last year had been < 7.0%. According to the KDIGO heatmap and KFRE the patient has moderate CKD but she is at high risk for cardiovascular and kidney complications. She is put on losartan 100mg. Six months later her eGFR was 40ml/min/1.73m2, potassium is 4.5 meq/l, UACR 300mg/gm creatinine & blood pressure is 130/80 mmHg.