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1. Which of the following are mechanisms that drive AChR antibody-mediated pathogenesis of MG?
a. Direct blocking of ACh receptor
b. Reduced number of receptors mediated by internalization and degradation of receptors
c. Deposit of complement and secondary destruction of muscle membrane
d. All of the above
2. Which of the following treatments work by removing circulating antibodies from circulation?
a. Prednisone
b. Plasma Exchange
c. FcRn Blockers
d. Both b and c
3. Factors that influence response to FcRn inhibitor therapy include:
a. Age
b. Severity of MG
c. Duration of MG
d. Sex
e. None of the above
4. Which of the below statement(s) are true?
a. Most patients with MG do not respond to FcRn inhibitor therapy until 3 months after treatment starts
b. Many patients with MG are intolerant of FcRn inhibitor therapy
c. About 40% of patients with MG achieve minimal manifestations status after the first 4-week cycle of infusions
d. Both a and b
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