• Journal Supplement to The American Journal of Cardiology


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  • 1. Which of the following variant classifications can be used for predictive genetic testing?*
  • 2. Which patients with HCM should be offered genetic counseling?*
  • 3. When HCM runs in a family with no prior genetic testing, which of the following patients would be the ideal first person to undergo initial testing?*
  • 4. The classification of obstructive versus nonobstructive HCM is based on the following:*
  • 5. All the following maneuvers can be used to elicit a left ventricular outflow tract gradient except:*
  • 6. The following imaging modality is best suited for assessment of scar in the myocardium:*
  • 7. Which of the following drugs has been shown to reduce the need for septal reduction therapy (septal myectomy) in patients with symptomatic obstructive hypertrophic cardiomyopathy?*
  • 8. Mavacamten is currently approved by the FDA for use in patients with:*
  • 9. In patients with obstructive hypertrophic cardiomyopathy, mavacamten has been shown to:*
  • 10. A 53-year-old man comes for evaluation of his HCM. He reports mild dyspnea on exertion. Transthoracic echocardiography (TTE) showed normal left ventricular function, severe asymmetric septal hypertrophy with a maximum diameter of 1.8 cm, mild systolic anterior motion (SAM) of mitral leaflet, and mild mitral regurgitation. He has a resting LVOT gradient of 15 mm Hg. What is the next best step in the management?*
  • 11. A 66-year-old female is referred for potential alcohol septal ablation (ASA) for her HCM. She has dyspnea on exertion and complains of having to stop midway while climbing one flight of stairs. On evaluation her blood pressure is 100/60 and heart rate 53 bpm. Examination was consistent with dynamic left ventricular outflow tract obstruction, with murmur augmenting upon standing from a squatted position. Electrocardiogram shows sinus rhythm with left ventricular hypertrophy. TTE reveals maximal septal thickness of 2.0 cm with resting and provocable LVOT gradients of 30- and 120-mm Hg respectively. There is systolic anterior motion of anterior mitral leaflet with moderate mitral regurgitation. She takes 100 mg of metoprolol succinate twice a day. What is the next best step?*
  • 12. What is the most common type of HCM observed in patients undergoing surgical treatment?*
  • 13. Choose the correct option to complete the sentence - Symptomatic patients with low resting LVOT gradients (< 30 mmHg):*
  • 14. Which anatomical landmark helps guide the extent of septal excision during myectomy in patients with oHCM?*
  • 15. What factor is most frequently associated with residual obstruction and persistent LVOT gradient following septal myectomy?*
  • 16. A. Inadequate medication B. Insufficient depth of septal excision C. Insufficient length of septal excision D. Residual mitral valve regurgitation*
  • 17. Choose the correct option to complete the sentence - The risk of postoperative complete heart block requiring permanent pacemaker implantation:*
  • 18. Which one of the following is not a major sudden death risk factor in HCM?*
  • 19. Which of the following tests should be considered in the initial evaluation of sudden death risk in nearly all HCM patients?*
  • 20. Which of the following statements about HCM is false?*
  • 21. What initiative launched by the HCMA has resulted in substantially improved outcomes for patients with HCM?*
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  • Attestation: This activity is certified for a maximum of 8.0 AMA PRA Category 1 Credits™ with 8.0 Medical Knowledge MOC points

    Through an agreement between the Royal College of Physicians and Surgeons of Canada and the American Medical Association, physicians may convert AMA PRA Category 1 Credits™ to Royal College MOC credits.

    Through an agreement between the American Medical Association and the Union Européenne des Médecins Spécialistes, physicians may convert AMA PRA Category 1 Credit™ to an equivalent number of European CME Credits® (ECMECs®). These credits will be recognized by all National Accreditation Authorities in Europe with which the UEMS has a signed agreement of recognition of credits.

    Continuing Nursing Education
    AcademicCME designates this enduring material for a maximum of 8.0 CNE contact hour (8.0 CNE pharmacotherapeutic contact hours). Provider number P0491. 

    Continuing Pharmacy Education
    AcademicCME designates this continuing education activity for 8.0 contact hours (0.8 CEUs) of the Accreditation Council for Pharmacy Education. Universal Activity Number – UAN JA4008190-0000-24-005-H01-P
    Type of Activity: Application 

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