Common Dog Breeds with MDR1 Mutation (Anesthesia/Spay/Neuter Surgery Risk):
Collie (Rough and Smooth)
Australian Shepherd (Standard and Miniature)
Border Collie
Shetland Sheepdog (Sheltie)
Old English Sheepdog
German Shepherd
Herding Breed Mixes (due to the prevalence in herding breeds)
Anesthesia Risks for MDR1 Mutation Carriers: Increased Sensitivity to Certain Anesthetic Agents: Can lead to prolonged recovery times or increased risk of complications during and after anesthesia-related procedures such as spaying or neutering.