• What best describes your title?*
  • 1. There are two major TGF-β signaling pathways. Ligands and receptors that activate SMAD 2/3 and ligands and receptors that activate SMAD 1/5/8. To activate gene expression, which of the following is correct?*
  • 2. Sotatercept, a recombinant human ACTRIIA IgG1 Fc fusion protein, was evaluated in a phase III multi-center study with endpoints change in 6-minute walk distance and time to clinical worsening. The patients in this study were:*
  • 3. The World Symposium on Pulmonary Hypertension Association issued an update for the role of sotatercept for the treatment of patients with pulmonary arterial hypertension (PAH). The recommended algorithm includes accurate diagnosis, assessment of vasodilator response through acute vasoreactivity testing, and evaluation of risk level by response to initial treatment. It may be appropriate to start sotatercept on:*
  • How many patients do you currently see each month regarding pulmonary arterial hypertension?
  • Learning Objectives
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  • Do you feel this activity was fair, balanced, and free of commercial bias?
  • This educational activity will result in a change in my role as a healthcare team member.
  • Based on your participation in this activity, choose the statement(s) that applies to how your role as a healthcare team member will change:

  • Attestation:

    AcademicCME designates this enduring material for a maximum of 1.0 AMA PRA Category 1 CreditsTM.

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