LDI-Penn Medicine Research Laboratory RFP 2025

LDI-Penn Medicine Research Laboratory

Request for Proposals
Topic for 2026:
Leveraging Generative AI to Optimize Health Care Delivery

Submission deadline: November 10, 2025, at 11:59 p.m. ET

The Leonard Davis Institute of Health Economics (LDI) and Penn Medicine announce the 5th Annual Request for Proposals for the LDI–Penn Medicine Research Laboratory. This strategic partnership aims to advance LDI’s mission of generating generalizable health care knowledge and to produce actionable evidence that guides Penn Medicine’s operational decisions. Funded projects are reviewed with Penn Medicine leadership, and promising work may receive additional support for systemwide implementation.

This year, the Research Lab solicits proposals that improve the effectiveness, efficiency, safety, and experience of care delivery at Penn Medicine, focusing on how generative artificial intelligence (AI) can optimize health care delivery.

To review the full request for proposals, including research questions and program goals, please click here.

For general questions or questions about the submission process, email Penn LDI.

Principal Investigator
Name*

First NameLast Name
Email*
Proposals must be led by an LDI Senior Fellows. Please indicate your LDI Senior Fellow status.*

Yes, I am an LDI Senior FellowNo, please send me information on how to become an LDI Fellow.

Business Administrator
Business Administrator Name*

First NameLast Name
Business Administrator Email*

Proposal
Title of Proposal*
Amount Requested*
(up to $65k)
Does this project involve any of the following*

Human subjects or animalsRadioactive material/radiation producing equipmentInvestigational new drugs or new devicesPotentially infectious agents, including human blood or tissueCarcinogensIn vitro formation or recombinant DNA
** Note: As a condition of funding, PIs of all approved proposals must submit a letter from the university office of research administration that all human subjects approvals and other university regulatory requirements have been met for your project, but these approvals should NOT be obtained PRIOR to submitting the proposal to LDI.
Please upload submission as a single PDF document with Proposal Elements listed below.*

Browse Files

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Proposal Elements:
- Abstract (≤250 words)
- Project Description (≤3 pages, single-spaced, 11pt font, 0.5-inch margins), including:
  - Aims & Significance (1 page)
  - Scalability (0.5 page)
  - Research Plan & Methods (1.5 pages: data sources, measurement, analysis plan)
- Budget (≤$65,000, itemized with justification; may include LDI analyst support, staff salaries, consultants, supplies; excludes travel, equipment, indirect costs). Faculty salaries are not included. To include an LDI analyst with experience pulling data from Penn Medicine’s data store and warehouse, please contact Jibby Kurichi for cost details.
- Timeline & Milestones quantifiable 1-year timeline; include quarterly milestones for accountability and required quarterly check-ins, and alternative strategies for achieving milestones
- PI Biosketch following NIH format, with publications and support, limited to 2 pages
- Other Pending/Funded Proposals for overlap check
- Co-Investigator Biosketches ≤2 pages each
- Operational Partner Letter of Support uploaded in appendix; must confirm project’s value, feasibility, and long-term potential
- Appendices limited to essential supporting materials, e.g., survey forms, admin letters
To review the full request for proposals, including research questions and program goals, please click here.
LDI Funding Opportunity: Applied (Project Year 2026)

LDI-Penn Medicine Research Laboratory
Should be Empty:

LDI-Penn Medicine Research Laboratory

Topic for 2026:Leveraging Generative AI to Optimize Health Care Delivery

Topic for 2026:
Leveraging Generative AI to Optimize Health Care Delivery