• 1. A 50-year-old man has type 2 diabetes that has been well controlled for 5 years. Over the past 6 months, burning numbness in his feet has worsened quickly. He now has bilateral foot drop, a Charcot joint, bilateral carpal tunnel syndrome, trigger fingers, and lumbar stenosis, and he was recently diagnosed with HFpEF. EMG/NCS shows a length-dependent axonal sensorimotor neuropathy with no signs of demyelination. What is the most appropriate next step?*
  • 2. Which statement about hATTR-PN therapy is best supported by the evidence presented?*
  • 3. The patient from question 1 has a confirmed pathogenic TTR variant (Ser97Tyr) and AL amyloidosis has been ruled out. He has HFpEF, a borderline echocardiogram, and a non-healing plantar wound. He has two adult children, ages 22 and 26. Which plan best reflects individualized care with shared decision-making?*
  • Which of the following best describes your title?*

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