Discovery Clinical Investigators

Please review these instructions before preparing a proposal.

Criteria for application:
Minimum of two sites required to apply (multi-institutional research study). Main investigator and must have a collaborator.

All proposals will undergo a formal review by the Discovery Steering Committee.
The research plan (questions 6 -16) in the application should be concise and limited to no more than 6 pages. The research plan includes specific aims, background and significance, preliminary studies (where applicable), and research design and methods.
The research plan should describe any assistance requested from Discovery (i.e., generation of data sets, data analysis, study sites, etc.)
It is expected that the results (positive or negative) of all approved Discovery studies, including those considered non-publishable by the study's investigators, will be presented to the Discovery Steering Committee within six months of study completion.
The Discovery Steering Committee should review all manuscripts resulting from the study prior to submission.
All study investigators must submit any conflict of interest

CHECKLIST
- All investigators have agreed to participate in this project.
- The statistical section prepared by biostatistician
- Scientific questions 6 -16 are prepared with font size 11 or larger.
- Scientific questions 6 -16 are < 6 pages in length.
- Institutional Review Board / Data and Safety Monitoring Plan
- Biosketches are included for primary investigators
- Instructions for preparing sub-studies and ancillary studies have been reviewed

Bio Sketch Template: LINK HERE (Word Document)
(Download template before beginning application or open in a new tab)

1. Project Title:

2. Principal Investigator Information:

Name

First Name Last Name

Degree

Mailing Address

Street Address

Street Address Line 2

City State / Province

Postal / Zip Code

Institution

Department

Email Address

example@example.com

Phone Number

Area Code Phone Number

3. Abstract

State the broad, long-term objectives, specific aims, and relevance. Describe concisely the research design and methods for achieving the goals. This abstract is meant to serve as a succinct and accurate description of the proposed work when separated from the application and should be no longer than one page.
(You may copy - paste content in the text below)

Abstract

4. Performance Sites:

(for adding additional information, please use the comment section at the end of the application)

5. Key Personnel:

(for adding additional information, please use the comment section at the end of the application)

SCIENTIFIC PROPOSAL (Question 6 to 16, limit total - 6 pages)

You may copy - paste content in the text boxes below

6. Specific aims/hypotheses:

7. Significance:

8. Innovation:

Research Design:

9. Preliminary data including investigator credentials:

10. Study Design:

11. Inclusion and Exclusion Criteria:

12. Endpoints:

13. Statistical Analysis:

14. Timeline:

15. Project Implementation/Dissemination Plan:

16. Ancillary Studies:

OTHER INFORMATION:

17. Human Subject Considerations (Risk, Benefit, Informed Consent):

18. Bibliography:

(suggested limit of 25 references)

19. Discovery involvement (how can the network help with the project). Check all that apply:

Methodology Support Outreach to other organizations Outcomes Support Ethical Considerations Support Administration (program management) Software Assistance (REDCap Cloud) Data Analysis Patient Engagement

20. Investigator Bio sketch:

Browse Files

Please use the biosketch template provided in the instructions above and attach up to 5 PDF documents.

21. Comments:

(optional)

Discovery Clinical Investigators - Application