Root Cause Protocol list of Seats on the Ferrous Wheel! Crutch/Conditions/Dis-ease/ Genetic reference and more.
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Accutaine
Accutane is POISON, esp. to Retinol, WF Vit-A. Lack of Vit-A KILLS Ferroxidase production, which then CAUSES UNBOUND COPPER. Please Copernicans, STOP referring to booga-wooga “Unbound Copper” & be silent about the RAGING Iron killing her Mg status that is CAUSING Suicidal thoughts & Actions. Folks who contemplate/take their lives have the LOWEST Magnesium (J.I. Rodale discusses this in his 1962 book on Magnesium [available at http://mgwater.com Read Chapter 19]) Blood donations, RCP w/ EMPHASIS on CLO, & EFT or Emotion Code...please watch the videos Morley and KK have done about accutane. I think the first ‘what did Morley learn this week’ had the beginning, and week 2 had more. Or else weeks 2 & 3.
Acquired Immune System
Runs on Copper, Infection = copper status is weak
Acne
"Acne is showing a need for retinol (vitamin A), bioavailable copper, and also Morley has talked about it being a reflection of our liver working on getting things 'out'. When you add to that the hormonal link, it's even more confirmation of the root cause being the minerals at the 'back end' of things. The beef liver, the retinol from cod liver oil (+ grass fed butter + eggs) are really helpful for many aspects. The liver also being helpful for other things too, including B vitamins and copper. The whole food c of the protocol helps your bioavailable copper. Bee pollen also assists with bioavailable copper (so these are helping with skin/connective tissue repair and renewal). If need something Quick: you can use milk of magnesia as a mask. You would need to mix it to a thicker consistency. Acne is based on propionum bacteria's activity. Bacteria feed on iron as all pathogens. Lactoferrin sequesters iron... it really works ! Any issues that appear on the skin are a direct mirror image of the gut/ lining basically if you were to turn inside out the gut lining & skin would replace each other they are apparently one & the same. I would def support gut/ liver in whatever parts of the protocol are suitable. Aloe Vera gel straight from the plant applied topically several times a day, even consumed as its soothing & healing for the gut. Manuka honey... topical. Red palm oil topical- ***aloe can be irritating for some people, those who are extremely sensitive sort.. What is the stress component before and now? Organic calendula cream, mag, Innate Vit C (over Pure Radiance), upping the beef liver and Jigsaw CLO (over Rosita's) has made a world of difference. (eczemahoneyco.com) Manuka worked a treat on itchy, open chicken pox. I’ve also used a balm with wild rose seed, Shea, hemp and starflower oils which have worked on open sores in the past. May not be making hydrochloric acid in stomach. Need to take a hcl supplement before each meal to help break down food. Please do not take it after a meal. After a couple of weeks one should be able to tolerate the cod liver oil as well. You can buy the supplement on Amazon. https://www.amazon.com/Vital-Nutrients.../dp/B002ATPALI. I like this one because it has gentian root which is a bitters and helps stimulate making your own hCl.
Another alternative is drinking Apple Cider Vinegar before each meal. Also,Purely E, Nutiva Organic Red Palm oil topically for skin issues like acne, scars
Adrenal Insufficiency
LOW TMA MANGANESE: After years of TMA testing, we routinely have found low manganese levels in the hair of patients with hypoglycemia (low blood sugar), hypothyroidism, adrenal insufficiency, kidney problems, and diabetes.(TE117)
Adrenal fatigue is fat deficiency. (WAP)
Adrenals love retinol, there is a sympathetic relationship between retinol a and copper. Can't absorb copper (fat soluble) without fat (esp animal retinol a).(MR)
Balancing our electrolytes are done as "Part of" rebalancing your FULL mineral status for optimal health. Minerals work together NOT in isolation. Electrolytes are chemicals that form electrically charged particles (ions) in body fluids. These ions carry the electrical energy necessary for many functions, including muscle contractions and transmission of nerve impulses.
The adrenals also require FAT (From Animal Tissue) to heal, and that means Retinol A. The Retinol A is also needed to counteract the damage from the hormone D intake and to try to lower her D levels. Watch out and avoid all products fortified with D, such as almond milk, rice milk, milk, cheeses, juices, ice cream, yogurts, etc. (VE)
Alcohol
So let's learn from this...o Those LOW in Bioavailable Copper have LOW Dopamine and thus HIGH Craving for Alcohol (It stimulates Dopamine synthesis) o HIGH Alcohol BURNS OUT Magnesium and Copper in the Liver and the body due to the metabolic actions needed to burn that alcohol, the fastest sugar on the Planet... o LOW Copper and LOW Mg in the Liver, leads to HIGH Iron in the Liver, the Heart, the Brain, etc...It doesn't take Rocket Science to figure out why [someone who drinks] has a HIGH Calcium score. Trust me, this has MORE to do with Alcohol, Iron, Magnesium, Bioavailable Copper... Calcium is just metabolic after affect following the chaos of the above ^^^…(MR)
Alcoholism
Alcohol prevents the absorption of thiamine (B1) and depletes magnesium, whole food C, niacin and several other minerals. This can cause a severe mineral imbalance which causes a severe condition called Wernicke's Encephalopathy which can result in very severe brain damage, muscle paralysis, loss of ability to walk, loss of cognitive function, loss of memory and even permanent disability leading to the need for permanent institutionalization for 24 hour care. When alcoholics are taken to the hospital for treatment they must be given IVs containing all of these nutrients, and more, for three days at a minimum to restore nutrients to prevent permanent brain damage. It must be caught early enough to prevent permanent brain damage. Books have been written on the need for niacin and other B vitamins to make it much easier to abstain and withdraw from alcohol. Google niacin and alcohol withdrawal and read the books and you will learn that the founder of A.A. heavily advocated the use of niacin, etc to help people overcome alcohol addiction . The RCP recommends natural food based sources of B vitamins and recommends whole food C and also advocates the need for magnesium, etc all of which support replenishing the minerals lost due to alcohol dependence and make it much easier to abstain.
ALS - (Amyotrophic lateral schlerosis) also known as Lou Gehrig's disease
Researchers have found that an imbalance of iron to copper may play a role in Parkinson's disease as well as other neurological disorders. People who died of Parkinson's disease were found to have increased iron accumulation and low copper levels in areas of the brain that is affected in this condition. This excess Iron has also been found in patients with ALS (amyotrophic lateral sclerosis) also known as Lou Gehrig's disease. Tissue damage caused by excess iron is due to its effect of generating free radicals or lipid peroxidation. Copper, on the other hand, protects from this type of free radical formation in neurological tissues. Iron and copper are closely related. Iron cannot be utilized by the body without adequate copper reserves. A person with a copper deficiency will retain iron because the body will stop eliminating it. ff this person also ingests large amounts of vitamin C, the iron overload will multiply further as vitamin C enhances Iron absorption, while antagonizing copper absorption.(TE111)
Alzheimers
Iron can accumulate in free form in any body tissue under conditions of iron overload. That is why iron excess causes such a wide variety of illnesses. The most dangerous feature of iron is that it is attracted to, and deposits in, damaged tissue. Thus, the neurofibrillary tangles of Alzheimer’s, the substantia nigra of Parkinson’s, the atherosclerotic plaques of coronary artery disease, the inflamed joints of arthritis, the pancreatic islet cells of adult-onset diabetics all display increased levels of free iron. There is no way to tell whether the iron initiates the disease or if the diseased tissue attracts the iron which then exacerbates the condition. But either way, free iron in any body tissue is dangerous. (Iron—The Most Toxic Metal18) • Neurological Degeneration: Parkinson’s & Alzheimer’s o The brain is a major target for excess iron. Accumulation of iron in brain tissue either causes, or contributes to, neurological diseases such as Parkinsonism and Alzheimer’s disease. Brain and nerve tissue iron accumulation is now recognized as a cardinal feature of most, if not all, neurodegenerative diseases. the role of iron in the neurofibrillary tangles in Alzheimer’s disease and in nodules surrounding demyelating nerves is still unclear. It is likely that both pathways make a contribution.(Iron—The Most Toxic Metal 18,19,67,69) very important research in 2010 by Duce discovered that there's a form of ferroxidase, up in our 28 brain, that's called amyloid precursor protein. Anyone who's worried about Alzheimer's knows about APP. Well they also know that when APP gets oxidized, gets rusty, it turns into what's called amyloid plaque. Amyloid beta plaque, right? [ Dr. Ben] Alzheimer's. [ Morley] And what Dr. Duce and his team discovered, is that zinc, unlike any other metal, kills the ferroxidase function of amyloid precursor protein.(RCP101 transcript) Consales et al, 2012, “Electromagnetic Fields, Oxidative Stress, and Neurodegeneration” https://www.hindawi.com/journals/ijcb/2012/683897/citations/ Please note that the 1st study noted ^^^^ (Maaroufi et al, 2014) is a very provocative one that chose to combine EMFs (900 MHz) with Iron loading on the experimental rodents… The sentence that REALLY caught my “eye,” (pardon the pun…) was the following: “A link between EMF, iron accumulation in the brain and neurodegenerative disorders including Parkinson’s and Alzheimer’s diseases has been suggested.” Morley - Alzheimer's is high copper BUT it is still low ceruloplasmin. Alzheimer's and Parkinson's are on the opposite side of the spectrum with copper/ceruloplasmin metabolism. Alzheimer's is L iron and H copper in the hippocampus - serotonin gets oxidised. (high copper/ high ceruloplasmin = low bioavailable copper because most of the ceruloplasmin is the immuno reactive protein not the ferroxidase protein.) Parkinson's is H iron and L copper in the substantia nigra and dopamine gets oxidised. ( Low copper / Low ceruloplasmin = low bioavailable copper because copper and ceruloplasmin is low - again - we don't know how much of the ceruloplasmin contains the ferroxidase enyme or the immuno-reactive one ) RCP enables to help both cases - because it focuses on ceruloplasmin - increased ceruloplasmin aka ferroxidase, it can move the iron/copper out respectively.
Antacids
Antacids containing aluminum hydroxide prevent the absorption of calcium from the intestinal tract
Anemia
Often thought of as “Iron Deficiency,” but in 1855, Dr. Theophilus Thompson (in London) published the first known article about curing Anemia using Cod Liver Oil. And in 1934, Drs. Whipple, Minot, and Murphy shared the Nobel Prize for curing “Anemia,” and "Pernicious Anemia" (aka. "Iron Deficiency caused by lack of Vitamin B12") with one product: Beef Liver! Hmm… While Beef Liver does have some Iron, the KEY to these solutions lies in the naturally occurring Vitamin A (aka. Retinol), and its ability to make Copper “bioavailable.” A well-established, but often overlooked fact, is that Inflammation CAUSES Iron to present low in Iron blood tests. (Roy, Andrews, 2005; Wessling-Resnick, 2010).
Anemia of Chronic Inflammation
Anemia of Deficiency
Iron Constipation - definition - too much iron is causing constipation (digestive) iron toxic = copper deficiency Not anemia of iron deficiency - but rather IRON Constipated.
Antibiotics
Destroy Copper Liver Enzymes. (They are supposed to be in our liver keeping us in balance) ABX mobilize Copper into the bloodstream. (Copper is antbacteriocidal with contact). When COPPER leaves the LIVER, IRON replaces it. Minerals stripped with use of Cephalosporins: Cephalosporin antibiotics: Cefaclor (Ceclor) B7,calcium, CoQ10, Folate (B9), Glutathione, Iron, Magnesium, B12, B3, Potassium, probiotics, B6, B2, B1, C, D, Cefadroxil (Duracef) Cefazolin (Ancef, Kefzol) Cefixime (Supra’s) Cefoxitin (Mefoxin) Cefprozil (cefzil) Ceftazidime (Ceptaz, Fortaz,Tazicef, Tazidime) Cefuroxime (Ceftin) Cephalexin (Keflex) calcium, Folate (B9), Glutathione, Iron, Magnesium, B12, B3, Potassium, probiotics, B2, B1, C, D, doxycline destroys copper status I would STRONGLY advise against ABX as they destroy your Copper-dependent enzymes in your LIver and will ONLY add to your Iron burden due to the axiomatic relationship of LOW Copper to Iron ACCUMULATION... I recommend EFT to ALL folks that I work with. WHY?!? It's quick, simple and RELEASES the FEARS that folks with Chronic conditions ALL HAVE... There may be value in the "re-training," but right now, you need to Dump your FEARS and your IRON -- those TWO are what's MAJORLY in the way in your recovery. (I've seen this dynamic duo in HUNDREDS of clients over the years...) And please, you MUST work with a Practitioner to do EFT properly... WHY?... Because folks with HIGH I.Q. are CONTROL FREAKS, and have a hard time "letting go!"...
Anti-Oxidant Enzymes
There is a NETWORK of Anti-Oxidant Enzymes that are designed to STOP the Iron-induced Oxidative Stress...: o MASTER Antioxidant Enzyme: Ferroxidase o Superoxide Dismutase (I, II, & III) o Catalase o Glutathione Peroxidase (it's what enables Glutathione to work!) o Paraoxinase o Haptoglobin o Hemopexin o to name but a few.... These rely on the Bioavailability of Copper, although the SOD II that's found INSIDE the Mitochondria "keys" off of Manganese. But what's UBER important to understand is that the Oxidants get made inside the Mitochondria when Complex IV (Cytochrome c Oxidase) of the Mitochondria is NOT able to properly "Activate" the Oxygen (O2) and turn it into Water (2H2O)... And WHEN that doesn't happen completely at Complex IV, it signals to Complex III to MAKE OXIDANTS, otherwise known as Superoxide (*O2-)... And WHY does Complex IV STOP working properly?!? LACK OF COPPER to RUN & REGULATE that key Complex... Cells FOCUS on ONLY TWO KEY JOBS in our body: o Create Energy... o Clear Exhaust... BOTH REQUIRE BIOAVAILABLE COPPER... This is NOT Rocket Science, but faaaaaaar too many practitioners want you to think it does...
Anxiety / Depression
Morley Robbins: A lot of people have anxiety, and where is this anxiety coming from? Well it turns out that there is a conversion of glutamate which is the neurotransmitter that's highest in the human body and there's an enzyme that turns that glutamate into GABA, the calming neurotransmitter. (Glutamate kind of stimulates and irritates, and GABA calms you down). Well that enzyme is called glutamic acid decarboxylase. That's a big word, but what makes that enzyme work is magnesium, B1, B2, B3, and B6. And here's what's interesting about it. When we're under stress, what leaves the body really fast? Magnesium and B vitamins, cause they're water soluble. And then that enzyme doesn't work and then you have greater anxiety. Now what's fascinating is that the psychiatrist have turned that G.A.D. into general anxiety disorder. And I'm not sure they even know about the enzyme. But that's the importance of B vitamins. That's just one example of the profound role that the B vitamins play in synergy with other minerals. But it provides tremendous balance and our awareness and perception is completely different because of those B vitamins.
Apolactoferrin vs Lactoferrin
Lactoferrin to build hemoglobin and Apolactoferrin to lower iron burden.
Appetite
Ascorbic Acid Whole Food Vitamin C
Wholefood Vit-C — NOT Ascorbic Acid — has 4 Copper atoms INSIDE the Tyrosinase enzyme at the core of that Vitamin Complex. Ascorbic acid undermines the ferroxidase enzyme function. The whole food vitamin C complex has seven parts. At the core of that complex is an enzyme called tyrosinase. Inside tyrosinase is a three-sided pyramid that has copper at all four points. It's it’s what allows us to manage neurotransmitters. It’s what allows us to manage the process of melanin in our body. Ascorbic acid has also been shown to increase iron absorption
Ascorbic Acid Whole Food Vitamin C
Wholefood Vit-C — NOT Ascorbic Acid — has 4 Copper atoms INSIDE the Tyrosinase enzyme at the core of that Vitamin Complex. Ascorbic acid undermines the ferroxidase enzyme function. The whole food vitamin C complex has seven parts. At the core of that complex is an enzyme called tyrosinase. Inside tyrosinase is a three-sided pyramid that has copper at all four points. It's it’s what allows us to manage neurotransmitters. It’s what allows us to manage the process of melanin in our body. Ascorbic acid has also been shown to increase iron absorption
Asthma
Caused by a mold that grown in the lung tissue = too much iron in the lung tissue - why? Not enough copper to keep it in check
Atrial Fib
the BIGGEST cause of BOTH Magnesium Loss and Atrial Fibrillation is Excess, Unbound Iron: https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.113.005837 When Copper is NOT Bioavailable, Iron will begin to STORE and become UNFunctional... And as we age, Iron gets stored in the Liver, Heart, Endocrine Glands, Kidney, Joints and eventually, our Brain... (Yes, ALL of the Neurodegenertation that pervades Society is from this dynamic...) So, adding Mo' Maggie is good for your SYMPTOMS of A-Fib... But, if you wish to CORRECT this chronic condition and bring your CopperIron Metabolism BACK into proper regulation & function, then I would STRONGLY advise you to head on over to http://rcp123.org to learn about the Root Cause Protocol that is UNIQUELY designed to RESTORE Bioavailable Copper & bring your Iron back into regulation... Last licks, World-renowned Copper expert, Leslie M. Klevay, MD, ScD wrote a series of paper (2000-2010) where he outlined the 80+ Anatomical, Chemical and Physiological DEFECTS in the Human Heart from Copper deficiency... I can assure you, A-Fib is but ONE of those many, many, many conditions affecting your Ticker...
Atypical Supplements that might be needed:
Manganese Amino Acid Chelate, Kal (some ingredients B1, B6, Niacin, Iodine etc.)
Calcium Lactate
Copper Liver Chelate
Catalase
Bernard Jensen Chlorophyll
Kali Phos 30x
Autoimmune Disease
ALL autoimmune conditions are triggered by Iron-Induced Oxidative stress. That implicates that a LACK of Ceruloplasmin, coupled w/ an excess of unbound Iron is the metabolic engine for this process.
Barriers to the RCP working:
YOUR SUCCESS with the RCP will depend on you 1. Getting the IRON out (through donation or gentle chelation) 2. Dealing with TRAPPED OR HIDDEN EMOTIONS 3. Dealing with HISTAMINE ISSUES through Allergy therapy and emotion work.
Beef Liver
Liver has 2X Copper to 1X Iron and it's also the HIGHEST source of Retinol on the Planet.
Bioavailable Copper -
Copper has profound functions in the body, principally focused on creating energy (Cytochrome c Oxidase) and clearing exhaust (Integrated Antioxidant System). But the Copper must be “bioavailable”, which means Copper needs to be “complexed” in a network of proteins and enzymes. And this doesn’t happen magically. Retinol is an essential nutrient for loading Copper into Ceruloplasmin.
95% of Copper in the blood is “complexed” in Ceruloplasmin.
Bioidential Hormones
They affect the copper/iron dysregulation 1960s important research - Uni Michigan (Ann Arbor) - three patients, published in Nature, studied ceruloplasmin protein from the three people. He gave them birth control pills (“really crude back then”, right?) and he studied their Cp changes. It changed the Cp level (NOT activity) from 35 to 76. What does that mean? There was an immuno-reactive process taking place where the protein is being compromised and there was an inflammatoryprocess taking place in the body. It is a known that BCP cause magnesium deficiency, copper proteins (like Cp) to be breached, cause Cu to be released from the Cp protein and other enzymes, and cause inflammation. Where’s the inflammation coming from? Cu + Mg being compromised, Fe is going up in the tissue (that’s what is inflammatory, Fe in the tissue). Morley then found articles on oestrogen - pumping in oestrogen causes similar reaction >>>>>>>>>>>>>> I am forever amazed at how folks point the fingers at Minerals that MTHR NATURE intended to be INSIDE our bodies, and blow past the Synthetic -- YES, they may be "identical,” NO, they are NOT NATURAL -- Hormones that they are taking... If hormones were a "salt," a pinch of a hormone would SALT 9 TONS of Potato Chips! -- that’s enough to FILL the average Football Stadium.... I would strongly encourage you to do the recommended mineral Testing (HTMA and FULL Monty Iron panel) and then engage in a consult that is DESIGNED to UNCOVER the set of "Stressors!" that CAUSED your mineral dysregulation, that then CAUSED your enzyme dysfunction, that then CAUSED your symptoms to appear... There are NO Effects without CAUSES... This Process of the RCP Consult, coupled with the RCP Protocol is designed to EDUCATE, ENLIGHTEN & EMPOWER folks to the TRUTH of their metabolic issues... And when you FULLY understand HOW your symptoms REALLY happened, you are MOTIVATED to engage in the RCP Protocol to address the UNDERLYING IMBALANCES that the need for "Bioidentical" Hormones imply... I can ASSURE you, after completing over 5,000 Consults, that Iron CAUSES the metabolic chaos that suggests that Hormones are not "working right..." Address the IRON-ic ORIGIN of this problem, and the demand for "Bioidenticals GOES DOWN..."
Bipolar
Bipolar RCP I have actually been doing a ton of research about so called personality disorders and I'm convinced that most (probably all) fall into the same realm as all the other labels and diagnoses that we as RCP Consultants know are really just the same thing - mineral dysregulation stemming from stress. In the case of bipolar 2 it is statistically likely that the stress originated as a tramatogenic family environment in childhood and has continued throughout adulthood by overactive stress responses that were developed as adaptive strategies as a child. I think we as RCP Consultants should be aware that personally disorders are just more labels that lead people in the wrong direction for true healing.
Blood Donation
The removal of blood triggers the release of EPO in the body, which brings iron out of stores and mobilizes it into new blood cells.
The body SHOULD be doing this by itself (moving the iron from the stores to the blood), but when ferroxidase within ceruloplasmin is low, the copper and iron it transports cannot move around. The EPO bypasses that aspect and forces the body to mobilize the iron out and about. By doing this, it gives the body a chance to have less inflammation, which reduces the pressure on mag and ceruloplasmin, which means better movement of iron and copper around the body via ferroxidase (& so on). Hemoglobin is the test used to determine donation at the blood bank. Hydrate well for 2-3 days prior. Have a fatty meal a few hours prior to donation. Keep your hands warm. Bring the AC and snacks for after.
# Adrenal cocktail before and after donation
# Good savory meal a couple of hours pre donation. I have bacon and eggs. # Heat pad on the arm that you donate from so the veins are happy and not hidden. # Adrenal cocktail straight after and snack of sweet potato chips, dark chocolate and nut butter or cheese. # After the donation keep up the fluids and sleep early. # Concentrate on extra hydration in the coming days. # Then visualize beautiful new blood being made
Blood Pressure
NOT an admin/mod/RCPC post but relevant from NaturalNews (link cited). HIGH BLOOD PRESSURE - isn't a disease, it's just a noticeable symptom of a physiological imbalance with a biological cause. One of the most common biological causes of this symptom is a mineral deficiency - Specifically: Potassium. Potassium is a crucial mineral for restoring healthy blood pressure balance in your body, and when you don't have enough potassium, symptoms can start to emerge that may eventually be diagnosed and labelled as "high blood pressure." Many population studies have found links between low potassium intakes and an increased risk of high blood pressure and death from stroke. Increasing the amount of potassium-rich foods in the diet can lead to a reduction in high blood pressure. The ratio of sodium to potassium in the diet appears to play an important role in the development of high blood pressure. The typical Western diet is low in potassium relative to sodium. When it comes to lowering blood pressure, potassium packs a powerful punch. Scientists began studying the effects of potassium on high blood pressure as early as 1928. Now a major study of 300 nurses shows that potassium can lower your blood pressure even if it's in the normal range. Good sources of potassium are dried apricots, avocados, dried figs, acorn squash, baked potatoes, kidney beans, cantaloupe, citrus fruits, and bananas. You can also buy potassium supplements. High potassium foods help lower blood pressure, but potassium exhibits additional powers to prevent stroke directly regardless of blood pressure, says University of Minnesota hypertension expert Dr. Louis Tobian, Jr. https://www.naturalnews.com/027407_potassium_blood...
Blood Type O
Type 0 Blood Type - (based on the book Eat Right for your Blood Type) type 0 carnivore of the highest order sugar and meat help you make dopamine
Blue Light
I just saw in my (Free!) blue light blocking app (Twilight) that the Melanopsin photoreceptor in the eyes sensitive to a narrow band of blue light (460-480nm) which suppresses MELATONIN production. Guess what minerals are needed to make melatonin (found in interviews?) So the artificial blue light suppresses melatonin production....which means it stops CERULOPLASMIN production! UPDATE: Special thanks to Tonya Koceja for pointing out what I missed. BLUE LIGHT BLOCKING glasses are an essential as well! (Especially if your Favorite Husband Cory Oestreich is totally against putting blue light blocking apps on the laptop.) Please know that I am NOT an expert in mitigating blue light, however, I will see if I can get permission to share some things that would be useful to help you pick out blue light blockers that work.)
Bowels
The bowels are “Toxic,” “Leaky” & “Constipated” for ONE reason: Excess, Unbound Iron. Iron FEEDS Pathogens & CAUSES Loose Tight Junction Connections, & DISRUPTS Bile & Peristalsis... In addition to the RCP & regular blood donation, I would encourage you to do MORE EFT to release your FEARS that you’re stuck, which you’re not... And you may want to watch the Tom Levy, MD, JD video AGAIN to see how he connects ALL OF THIS DIGESTIVE CHAOS TO IRON!... Stephanie Roberts https://youtu.be/NUjmwTwNCAI Here is one study about it https://www.ncbi.nlm.nih.gov/m/pubmed/17076689/?i=2&from=rooibos%20potassium%20channel
Brain Fog /Chronic Fatigue
KK: Brain fog is also attributed to ammonia release - Iron is definitely behind it, but when the ‘fog clears’, its ammonia not floating around. I have this reply from Morley saved from a post talking about glutamates and chronic fatigue... (August 2017) "An enzyme called glutamic acid decarboxylase (GAD) is needed for glutamate to make the conversion to GABA, but there are several factors that may interfere with this enzyme and impede the conversion process, which means a build up of glutamate and inhibited the formation of GABA. Response time may be delayed or capacity to convert may be impaired. It is believed that problems with the GAD enzyme may be the primary underlying issue that results in too much glutamate." [NOTE: Last sentence is in BOLD in the article...] GAD requires Mg, B1, B2, B3, & B6... Under "Stress!", Mg & B Vitamins are the FIRST to leave... It is VERY boring and NO drama to recommend these BASIC nutrients to ENSURE proper Glutamic Acid GABA balance... And while researching this a bit more to make sure that I had my facts down properly, I just learned that there is ALSO GDH enzyme, which is Glutamate DeHydrogenase, which ALSO converts Glutamate, but only in a LOW ATP environment... GDH keys off of ADP and creates Ammonia and a-Ketoglutarate (which can lead to excitotoxicity)... Given that Glutamate is the greatest occuring Amino Acid in our bodies, maybe we NOW understand the ORIGIN of the "Brain Fog" that sooooo many with CFS experience!” Alisha M. Soderquist The situation of a low ATP environment and GHD producing a-Ketoglutarate and ammonia explains now why I couldn’t tolerate the a-Ketoglutarate form of vitamin B6 before I began the protocol! Jacqui Soliman Healthy functioning mitochondria are crucial for overcoming chronic fatigue. Magnesium and bioavailable copper - both of which the protocol help you increase and get balanced - are crucial for healthy mitochondria. So the protocol should definitely help with chronic fatigue
Calcium Lactate
calcium lactate, as a way to help break down the calcium shell. It’s a very bioavailable form of calcium, and it literally invites the calcium in the tissue back into the bone.
Calcium Potassium channels/pathways
So what we are saying here is that Mg is most likely the main reason why potassium/calcium channels/pathways are blocked or sluggish. Since all ATP is actually Mg-ATP we start to get more proof that low magnesium can impede other areas of biology that Mg was never thought to have an active role in.
Calcium Shell
Cancer
Morley Robbins In my minerals-first world, Cancer is CAUSED by a LACK of bioavailable Copper and excess, unmanaged Iron, which whips up Oxidative Stress that ultimately leads to a change of Mitochondria from aerobic to anaerobic metabolism which we call Cancer... The LACK of Catalase is of paramount importance in keeping the body "Cancer-free" as it neutralizes the toxic oxidant, H2O2 (Hydrogen Peroxide) which is very disruptive... Now, here's the connection to Parkinson's... ALL forms of neurodegenerative conditions (AD, PD, ALS, MS, etc.) are CAUSED by a lack of bioavailable Copper >> LOW Cp >> HIGH Reactive Iron >> HIGH Oxidative Stress in the Substantia Nigra that affects Dopamine production and fine motor coordination. http://www.sciencedirect.com/.../pii/S0925443911001426 (This ^^^^ is one of hundreds of studies proving this mineral imbalance is at the CORE of this condition.) Last licks, and here's WHY you don't want to get near Radiation Therapy for Cancer Tx: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662108/ Hope that answers your questions... Morley Robbins: One of the most important books I read, was written by a dairy farmer, his name was Andre Voisin, and he published this book in 1957. He was originally from France, relocated to Great Britain, and he was a dairy farmer in Great Britain. The title of his book was called Soil, Grass & Cancer, and what he was lamenting was that there wasn't enough copper in the soil which wasn't getting into the grass, that his cows weren't getting in their daily diet, that was causing a copper deficiency in his customers, and it was causing them to get cancer. Now what's amazing about this, is that he was not your average dairy farmer. The book was 325 pages long, with 265 foot notes, which is notable. And the diagrams and the research that he had done about the origin of cancer was impeccable because he knew that, what is cancer? It's lack of oxygen. It's a metabolic state. That's what Otto Warburg understood. Otto Warburg knew that cancer was a metabolic shortage of oxygen, but it's not a lack of oxygen, it's an inability to use the oxygen. What's significant about that is that iron carries oxygen around the body, like a waiter. That's what hemoglobin does. Hemoglobin carries oxygen. It's a very important function, but copper is the critical mineral to make all of the oxidase and oxygenase enzymes work. There are about 30 of them. Only copper has the natural ability to activate oxygen so that it can enable the production of energy. The fact that cancer is the second leading cause of death, soon to be the leading cause of death, they say within two years, it'll crest heart disease. It isn't a lack of oxygen. It's the inability to use the oxygen. That's a very subtle distinction. Valerie Engh His iron is not low; it is dysfunctional due to the lack of ferroxidase enzyme function which requires bioavailable copper and retinol A. The iron increases the metabolic cellular dysfunction and therefore feeds the growth of the cancer. My husband was diagnosed with an intermediate grade prostate cancer in 2010. He donates whole blood regularly to get the iron out of the tissues and organs and prostate where it has been stored. He also takes IP-6, lactoferrin, stabilized rice bran, organic apple cider vinegar in water, green tea, quercetin, CoQ10, turmeric, food sources of iodine, boron, etc to regulate, chelate and remove the iron. He follows the RCP, takes the cod liver oil, grass fed beef liver, whole food C, digestive enzymes, etc. His PSA is remaining very low at 0.29 The boron has been shown to have an inverse relationship to prostate cancer and we also know boron is a Mg cofactor and boron also has an inverse relationship to iron. When bo-ron is too low, ...or too high..then the i-ron is dysregulated. I have saved a research study that discusses boron and prostate cancer and I can post it for you tomorrow, as I am traveling today and not at my laptop. Chemo really complicates the situation as it strips the bioavailable copper from the body; therefore, the mitochondria cannot make energy. The grassfed beef liver will provide back some of the bioavailable copper that he needs in Complex IV of the electron transport chain in the mitochondria to make energy. When the copper is stripped from the body, the blood vessels surrounding the nerves and the myelin sheath dies, then the nerves die and that is why the chemo causes peripheral neuropathy...All due to the lack of bioavailable copper that needs to be complexed within the ceruloplasmin protein to make the ferroxidase enzyme.
Candida
Excess tissue copper = conditions Candida Albacans yeast infection, hypothyroidism, Hydrogen peroxide induces candida to transform from the yeast form to the toxic fungal form the breakdown of sugars in an aerobic process is going to create hydrogen peroxide, so then it starts to feed on itself. That's exactly what happens. Let's remember, what's this candida living on? It's called iron
Catalase -
Another important Copper-dependent antioxidant enzyme that, similar to Glutathione, reduces H202 (Hydrogen Peroxide), principally in our blood, reducing Oxidative Stress (aka. “rust”). When there is sufficient Catalase in our blood stream, there can be proper production of Hemoglobin. Too much Hydrogen Peroxide (H2O2) will prevent optimal Hemoglobin production. Therefore, a lack of Catalase can be a KEY cause of “Low” Iron levels in blood tests. (aka. Having a low Hemoglobin blood test score.) But this has NO relation to the actual level of Iron inside the body as a whole.
Celiac Disease
Morley - Celiac - As best I understand it, "celiac" is stimulated by the fact that modern wheat is NOW sprayed with Glyphosate (RoundUp) BEFORE harvesting. Glyphosate has known properties of causing Liver Copper to drop, and Liver Iron to rise -- neither of which is beneficial to the person eating these products. Also, the fact that we "Iron Fortify" our flour, and have since WW II, only adds to this dynamic. Given that we are being exposed to ridiculous levels of Iron in our daily diet (food & supplements), this adds to the process of Oxidative Stress that is associated with celiac. This Oxidative Stress also has a decided impact on the Magnesium status of the body, as well... In terms of "Chicken vs Egg...", my guess is that "Iron Stress!" >> Mg Loss >> Increased Oxidative Stress! >> dynamics of celiac... That would be my working hypothesis. Missing in this model is the role of Anti-Oxidant Enzymes (SOD, CAT, GSH) which play a pivotal role in seeking to neutralize the effect of the Oxidants. These enzymes are dependent on bioavailable Copper and Ceruloplasmin. "Iron Stress!" wipes out their potency, as well... Hope that makes sense... Morley - Glucose oxidase gluten More people in the fake-news world of “Gluten Sensitivity” need to Study & MASTER this seminal overview of the Connection Btwn Copper Deficiency & Gluten/Celiac issues by Cleo Libonati https://glutenfreeworks.com/.../understanding-copper.../ She TOTALLY gets it! The enzyme in wheat flour is Glucose Oxidase. ALL OXIDASE ENZYMES require bioavailable Copper. Faulty Oxidase function, due to EXCESS IRON, creates excess H2O2 that is very disruptive to Copper deficient digestive tissue...
Ceruplasmin
When there is not enough ceruloplasmin ferroxidase enzyme (bioavailable copper) needed to make the iron FUNCTIONAL/(circulating) through the body, the lack of ceruloplasmin ferroxidase enzyme can also cause ferritin or other blood markers to be lower because the iron is sequestered out of the blood and stored in the organs. Ceruloplasmin is made in the following tissue:
o 1st, & foremost, the Liver...O the Brain (that tissue consumes Oxygen at a prodigious rate, thus Iron's high there, right?...o Kidney o Breast tissue o Gonads (other Endocrine glands?!?...o and Drum Roll, please... wait for it...o the Retina of the eyes makes 8X MORE Cp than the Brain!!! Think that metabolic NEED for Ocular Cp might be an issue with: o the prevalence of Blue light that burns up Cp...
o absurd intake of Hormone-D that affects Retinol (get it? RetinaRetinol?!?...) that affects Cp production?... o absurd intakes of Iron in our "D"iet?!?
Chemotherapy
Chemotherapy is basically a bulldozer. It just wipes out minerals.
Cholesterol
Will rise when >>there is too much unbound iron >>there is not enough bioavailable copper Issue never been cholesterol, the cholesterol gets oxidized by too much iron - it gets rusty. Leslie M. Klevay, MD, ScD ROCKED the world in 1973 to PROVE that too much Iron and/or too little Bioavailable Copper CAUSES Cholesterol to RISE... Elevated Cholesterol is NOT a “medical disease.” It is merely Clinical PROOF of CuFe Dysregulation... Only 30 Labs — world 🌎 wide — have re-affirmed & Re-enforced Dr. Klevay’s findings 45 yrs ago... “A” votre sante! iron oxidizes LDL, HDL has a copper dependent enzyme to help LDL from being oxidized. Rising low density lipids =backs up (means) low bioavailable copper, low ferroxidase and iron toxicity. Stephanie Jasky Yes, it does. The reason cholesterol is found in the arteries is because it’s repairing the damage iron oxidation, low copper is causing. With the proper fiber intake, addressing the copper deficiency, the body will recycle that cholesterol and clean out the arteries. Cholesterol didn’t cause the heart issues, it’s there to fix the problem of iron toxicity, low copper. Inflammation and low elastin/collagen is causing the damage to the arterial walls, cholesterol is a saving measure, but the root cause is never addressed in your doctors office. Stephanie Jasky DE (silica) and copper are the building blocks of elastin/collagen. So yes, DE helps stop the arterial weakening due to being needed for collagen. It is the SAME CuFe Dysregulation... Dr. Klevay identified 80 anatomical, chemical & physiological defects — in the Heart & Circulation— CAUSED by a LACK of Bioavailable Copper... Look 👀 NO FURTHER than that for your LOW HDL & your HIGH Triglycerides... IRON-ic, eh?!? Larry Feuer While I agree with & applaud your encouragement for ALL to read this article, the GREATEST tragedy on this Planet 🌎 is that Doctor’s have NO IDEA how to assess IRON HOMEOSTASIS— which is VASTLY different that “Iron Status!” The latter is based on the moronic & FLAWED blood test, Ferritin, which I have RENAMED “ERRORTIN,” due to its GROSS misinterpretation by Practioners that are CLUELESS about its dependence on Ferroxidase enzyme function to work properly... The Former requires understanding that Bioavailable Copper REGULATES Iron Homeostasis, which is NOT taught in ANY Practitioner training, outside of the Cupernican Institute. So yes, as I’ve been saying, & teaching, IRON IS TOXIC! But PLEASE, challenge your preferred health practitioner to learn HOW to measure its TRUE DYNAMIC in your body based on the FULL Monty Iron panel — NOT the “Errotin”-only blood marker! “A” votre sante! Cholesterol is ESSENTIAL to make "Stress!" Hormones, myelin sheath in the brain and a THOUSAND other things that are KEY to your good health... The FAKE NEWS NARRATIVE that "Cholesterol is BAD for your Health" has officially been deemed a LIE by the Leading researchers & clinicians: https://bmjopen.bmj.com/content/bmjopen/6/6/e010401.full.pdf Cholesterol is your FRIEND... And when it RISES, it's a clinical sign of LOW Bioavailable Copper. THAT ^^^^ was proven by Leslie M. Klevay, MD, ScD in 1973 and has been REPEATEDLY proven by 30 Labs AROUND THE WORLD... One of the greatest SCAMS on the Planet is to be "fearful" of your Cholesterol levels... "A" votre sante! Tracey Reiche Fillmore Ease up on your carbs (sugars, esp.) and INCREASE your grassfed Beef Liver (Chock FULL of Bioavailable Copper) and enjoy the transition of BOTH your Triglycerides AND your HDL... Please KNOW that the LCAT enzyme to convert LDL >>HDL is dependent on Bioavailable Copper! (Feel free to share that PEARL with your myth-informed practitioner!... ;-) ) Cholesterol exists in two states; high density, low density. Here we go again with one of those pesky enzymes, it’s called LCAT. That enzyme keys off of magnesium and copper and it turns LDL into HDL. Why is that important? Well, it turns out what the whole problem was LDL can get rusty if it’s exposed to iron. Healthy fats do not affect heart disease. Why does cholesterol show up in the blood? Because it's coming out of the liver which means liver stress. Liver stress = too much iron, not enough copper. Best source of info on how lack of copper causes a rise in cholesterol is Leslie Klevay, copper expert. Google "Statins Sinatra Women" Cholesterol is the base of a lot of important chemicals, like Vit D, and is the base of steroid hormones. When we are under stress we need more steroid hormones. Leslie Klevay in 1972 figured out that the rise in cholesterol in rodents and humans is due to a lack of copper. 22 labs around the world have verified his findings. There are 2 events taking place, the actual release of cholesterol into the blood stream and there's a change in conversion from LDL to HDL. Not sure why the cholesterol gets released into the blood stream other than maybe a stress response. Cholesterol is suppose to be in the liver. Conversion issues is the Lecithin-Cholesterol acyltransferase (LCAT) enzyme is what converts LDL to HDL. There is no bad or good cholesterol. The reason it became demonized is because LDL is more prone to oxidation. Iron is causing oxidation. The iron being put in wheat flour was building in the liver, when copper is low the body is forced to store the iron in the liver first. With the building iron you have a drop in copper in the liver, which will cause a cholesterol problem.
Ciprofloxin
Toxicity: vacuum that sucks magnesium and copper out of the human body Tendons are connective tissue that gets made and remade with a key enzyme Lysol oxidase Makes people super sensitive to their environment. Histamine is trying to save you from the environment because you are super sensitive it changes the energy dynamics of the cell, causes a flooding of water to try to flush out the toxins which is what historically would cause that reaction and the body is supposed to be able to break down those histamines with one of two enzymes.DAO or HNMT, both require magnesium bioavailable copper and B6
Citrus Pectin
The effect of citrus pectin on the absorption of nutrients in the small intestine. - PubMed - NCBI The effect of citrus pectin on the absorption of nutrients in the small intestine. - PubMed - NCBI  Search  The effect of citrus pectin on the absorption of nutrients in the small intestine. Sandberg AS, et al. Hum Nutr Clin Nutr. 1983. Show full citation Abstract The extent of hydrolysis of citrus pectin in the stomach and small intestine was studied by in vivo digestion in ileostomy patients. The effect of citrus pectin on ileostomy losses of fat, nitrogen, starch, sodium and potassium was also investigated as was its effect on the absorption of phosphorus, calcium, magnesium, zinc and iron. Six ileostomy patients were studied during 10 d while on a constant low-fibre diet supplemented with 15 g citrus pectin/d on days 5, 6 and 7. The constituents mentioned in (1) as well as neutral polysaccharides, uronic acids and Klason lignin were determined in the ileostomy contents and duplicate portions of the diet. Of the uronic acids derived from the citrus pectin 70-100 per cent was recovered in the ileostomy contents. The wet weight of ileostomy fluid increased by 314 g/24 h and dry weight by 24 g/24 h after consumption of 15 g citrus pectin. During the pectin period there was a significant increase in the amount of nitrogen, fat, ash, Na and K found in ileostomy contents, while the amount of starch was unchanged. During the pectin period the apparent absorption of Fe decreased significantly, while that of P, Ca, Mg and Zn remained unchanged. It is concluded that there is only limited digestion of citrus pectin in the stomach and small intestine. The slight increase in ileal output of nitrogen may either be due to decreased digestion and absorption of fat is more pronounced. In the 3-d study addition of 15 g pectin to the diet did not seem to impair the apparent mineral absorption from the small intestine except in the case of Fe. PMID 6307932 [PubMed - indexed for MEDLINE] Similar articles * Experimental model for in vivo determination of dietary fibre and its effect on the absorption of nutrients in the small intestine. Sandberg AS, et al. Br J Nutr. 1981. * The effect of wheat bran on the absorption of minerals in the small intestine. Sandberg AS, et al. Br J Nutr. 1982. * Extrusion cooking of a high-fibre cereal product. 1. Effects on digestibility and absorption of protein, fat, starch, dietary fibre and phytate in the small intestine. Randomized controlled trial Sandberg AS, et al. Br J Nutr. 1986. * The ileostomy model for the study of carbohydrate digestion and carbohydrate effects on sterol excretion in man. Review article Andersson H, et al. Eur J Clin Nutr. 1992. * Nondigestibility characteristics of inulin and oligofructose in humans. Review article Andersson HB, et al. J Nutr. 1999. See all Full website * NIH NLM NCBI Help ******************************************************* http://healthhubs.net/diabetes/pectin-improves-glycemic-control-in-diabetic-patients/
Cod Liver Oil CLO animal Retinol A
Retinol (as in from CLO) is the BACKBONE of Cp and it resonates at a certain frequency which is really important for the function of this enzyme. The same way a plant knows how to make chlorophyll, it’s by the green wavelength of light!!! The liver RUNS on Retinol – the largest organ in the body and when it can’t function properly, it will send it to the largest organ OUTSIDE the body – the SKIN!!! The liver needs to be full of retinol, BioA Cu, and Magnesium to get rid of the iron. We get retinol in grass fed beef liver and butter and pasture raised eggs.
COMT++
LOW Iron in the Blood typically means HIGH Iron in the Tissues... Your symptoms (Lyme, COMT++, High Estrogen, etc) are ALL signs of Excess, Unbound Iron. Your bloodwork is NOT being interpreted completely. Hormone Dysregulation and Unchecked Pathogens (they ALL live on Iron!) are simply FURTHER signs of CopperIron Dysregulation...
Constipation
RDA for potassium is 4700mg/day, less than that can impact bowel motility = constipation.
Consuming too much water not mineralized can wash out electrolytes, dehydrating at a cellular level. Too few electrolytes + too much mag = constipation for some, diarrhea for others.
Copper Deficiency
If you take just 20% of that copper out of the organism, everything goes haywire, you start losing magnesium and iron starts to build and starts to get stored. Fast oxidizer is vulnerable are three areas it will lose, it will lose calcium and magnesium under stress
DE
Doesn’t have B vitamins. Recognized to assist re: binding. Causes dehydration to parasites. Very effective to support the body. Has capacity to also to remove the iron: don’t know exactly how.
Dental Issues
Kristan Kershaw: Many of you are dealing with dental challenges - whether it's receding gums, bleeding gums or many other dental related aspects, the Root Cause Protocol will support your body in metabolically providing what is needed to strengthen what you have (at minimum) and for many of us, reduce pain/discomfort too. Years of bleeding gums for me despite taking care of my teeth, have now made way to healthy pink gums and no pain. I just found this article which you may be interested in reading. It has some notable omissions - no recording of ceruloplasmin at all, BUT it did interestingly find that copper deficiency was significant in those with severe tooth wear and reduced bone density. Morley's research presented in the past has already delved deeper than this - with the link between iron and copper balance being critical to mineral density, and the underlying availability of both being a bit issue... but this is a good starting point. How do we get more bioavailable copper? DO THE PROTOCOL! Whole food c, grassfed beef liver, magnesium... ;-) - moderator & Root Cause Protocol Consultant. Copper deficit as a potential pathogenic factor of reduced bone mineral density and severe tooth wear. - https://www.ncbi.nlm.nih.gov/pubmed/23797848 I've also found a mineral toothpaste which is really good and has helped me a lot too. The full protocol + this have been magical for me. I chose the Children's Toothpaste, but brushing with MoM is another fantastic option https://www.uncleharrys.com/mouth-care/toothpaste Bruxism - a sign a Magnesium deficiency. Utilizing EFT to "let go" of what we might be "holding on to" or to deal with underlying stress can also be beneficial. according to Jerry Tennant, each tooth is a circuit breaker for certain organs. That tooth may be associated with the gut meridian on one of those tooth charts. That's where I'm convinced a lot of issues stem from also. http://drgadol.com/meridian-tooth-chart/ or this one is pretty cool being more interactive http://naturaldentistry.us/.../meridian-tooth-chart-from.../ http://naturaldentistry.us/holistic-dentistry/meridian-tooth-chart-from-encinitas-dentist/?fbclid=IwAR2Omrhbxn3zrZP4rI2tebcx2OY_xmuMyiKpwmf778L-tZEOAhcoOBUabQg
Depression
Hormone D: How do you guys deal with low vitamin d levels? Even out in the sun and taking 5000iu a day I was barely hanging on. Now that I want to start this protocol I know it’s going to tank...I get very depressed and my infections flare up. Thanks. Get a sad light for the depression. In my opinion infections “flare” because you’re not on steroids. Get your 1,25D tested, with the other three things recommended as well. After you read the stuff here see if what you call low is truly low. Know the one you track, 25D, doesn’t do anything. It’s simply a substrate, which is stored in the liver. Your body wouldn’t even use 5000iu in a day. Your body doesn’t want it. It’s the lymphatic system that picks up D. Please stop thinking your body is stupid. If the human body was dumb many folks would be killing themselves with D. Rodenticide."the point is, you CAN get by without supplemental vitamin d. Your body is needing to convert what sun or light you get, into vitamin d. You eat foods containing retinol, continue to get magnesium and other nutrients, get the inflammation down and review where you are at with your excess, unbound iron, and your vitamin d will go up by itself. By supplementing with it, you are going to be pressuring SO many minerals and electrolytes which in turn put more stress on your other minerals and lead to more dysregulation. Jim has pointed out that lamps can be used to help get light to help you convert more d too, so if you cannot get sunlight, that's a helper. I would encourage you to get the full testing done, work with a consultant to help you connect your dots and understand how stress is related to all of what you are experiencing, and to get moving with confidence. I've seen a number of your posts where you seem nervous about doing it yourself or the change in mindset you are working on. Our experience tells us, the best outcome will be from you working with someone. I don't have the link handy, but I'm sure MJ Hampstead has shared it with you or could do so again ;-) " If you actually think taking D3 helps depression then this isn’t going to work for you. Being honest. Have you even read about D3 etc here. The stuff I have in here? You have a good 1,25D. The molecule of immune response that has a diurnal rhythm and an 8-12 hour half life. This molecule is why our bodies make D3. Period. you wouldn’t want to supplement D with raising 1,25D as a goal. That getting higher isn’t a good thing because it IS the molecule of immune response. It’s being requested to encode the genes to create your chemical and biological warriors. It’s a genomic response molecule. In fact I had to really think about it. I don’t know of anyone promoting increasing 1,25D. But it does increase in some folks. This is why it needs to be checked. Keep in mind this is the molecule the body monitors in the Calcium/pth/D axis. Drive it up and you increase calcium needs to the point you can get the body to induce osteoporosis. Calcium has to come from somewhere to match the insane increases in D serum levels. (It’s D that sets the level, the ratio never changes. Calcium must match D. If you read the action of rodenticide this is EXACTLY what happens to people but they don’t die they just destroy their bones. May be a kidney.) In serum, vitamin D binding protein-vdbp, transports the two forms of D, 25D and 1,25D around the body. But, 25D has 1000 times higher affinity (attraction) to bind with this carrier protein than does 1,25D. Can you see how too much 25D could create an issue getting the 1,25D where it needs to be when it's needed? We see this exact same thing with folic acid versus folate. Above you state this: Vitamin d 1, 25 hydroxy is 21, range 30-100 and that’s on 5000iu/day. You are taking D3. This measurement is of 1,25D. “At a typical daily intake of vitamin D3, its full conversion to calcifediol takes approximately 7 days.[3]“ That’s ^^^ 25D. One more step to become 1,25D. Can happen right away. But there’s no requirement for D3 to become 25D or 1,25D. Or ever hang out to be seen in your serum on the test. There are numerous analogues of D and there’s true storage. In fat. Like a fat soluble behaves. Calciferols (vitamins D), cholecalciferol (vitamin D3) and ergocalciferol (vitamin D2) are used as rodenticides. They are toxic to rodents for the same reason they are important to humans: they affect calcium and phosphate homeostasis in the body. Vitamins D are essential in minute quantities (few IUs per kilogram body weight daily, only a fraction of a milligram), and like most fat soluble vitamins, they are toxic in larger doses, causing hypervitaminosis. If the poisoning is severe enough (that is, if the dose of the toxin is high enough), it leads to death. In rodents that consume the rodenticidal bait, it causes hypercalcemia, raising the calcium level, mainly by increasing calcium absorption from food, mobilising bone-matrix-fixed calcium into ionised form (mainly monohydrogencarbonate calcium cation, partially bound to plasma proteins, [CaHCO3]+), which circulates dissolved in the blood plasma. After ingestion of a lethal dose, the free calcium levels are raised sufficiently that blood vessels, kidneys, the stomach wall and lungs are mineralised/calcificated (formation of calcificates, crystals of calcium salts/complexes in the tissues, damaging them), leading further to heart problems (myocardial tissue is sensitive to variations of free calcium levels, affecting both myocardial contractibility and excitation propagation between atrias and ventriculas), bleeding (due to capillary damage) and possibly kidney failure. "Typically, one isn’t taking in too much calcium from food sources per say, but instead from calcium supplements, calcium fortified food, and/or they have increased calcium absorption from taking high dose vitamin D3. Part of vitamin D’s job is to tell your body to absorb more calcium from your food, pushing calcium levels even higher in the body, and pushing potassium levels lower."
Detox
Detox requires energy and most people barely have enough energy to heal MIlk Thistle: Milk thistle: stimulates detox, attacks the guest, conflicts with the over-riding philosophy of the Root Cause Protocol: “strengthen the host”. Milk Thistle is a polyphenol which means it requires polyphenol oxidase which is a copper dependent enzyme. Morley Robbins: Please know that my approach is both counter-intuitive and counter-cultural. I approach these issues of metabolic imbalance VERY differently than most practitioners, regardless of their faith & orientation. The Root Cause Protocol is designed to awaken the innate healing within & support it with stimulating minerals & vitamins so that your body can do what it's designed to do: bring you back to balance! And I seek to bring energy to this process. The detox that ensues is natural & NOT forced. What most don't understand is that "detox" requires energy, & most clients are simply wiped out. And the part of your Brain that directs this process, the Hypothalamus, thinks 2,000,000 times FASTER than you & I can talk... Do you think it's going to miss ANY cells?!?... 😉 There is a KEY choice in healing: o "Attack the guest!" OR o "Strengthen the Host!" Chasing & worrying about "cell inflammation" is yet another "guest" to scare you with. The RCP is ALL about the supporting & nourishing your "host!" Hope that sheds new light... A votre sante! Stephanie Whaley Milk thistle can safely be taken long term, depending on the dose. A standard liver protectant dose is 175mg per day of a 30:1 seed extract standardized to 80% silymarin. Therapeutic and restorative doses can go upwards of 600mg daily.
Diabetes
Under Chronic Stress, the Magnesium LOSS Is relentless, esp. from a condition like Diabetes, which is a Clinical sign of HIGH Iron/LOW Bioavailable Copper... There are TWO SIDES to Diabetes: o Excess, unbound Iron CAUSES Insulin Resistance... o LOW Bioavailable Copper CAUSES Glucose Intolerance
Diet Soda
Diet Soda is BAD - “Artificial sweeteners seem to confuse the body’s natural ability to manage calories based on tasting something sweet. People tend to them overeat even if they drink diet soda. And get this: People who consume artificial sweeteners are twice as likely to develop metabolic syndrome, too. (2)” “Drinking more than four cans a day of soda is linked to a 30 percent higher risk of depression.” “Harvard researchers found long-term diet soda drinking causes a 30 percent greater reduction in kidney function.” “67 percent higher risk of type 2 diabetes compared to non-diet soda drinkers. (5) In fact, the artificial sweeteners may tamper with the gut-brain connection. This can lead to brain trickery that leads to “metabolic derangements.” those drinking diet soda daily were more likely to suffer a stroke or heart attack. They were also more likely to die from cardiovascular disease.” “Compromised Lungs Drinking soda, including diet soda, increases your risk of developing asthma and COPD symptoms.” “Aspartame, a common artificial sweetener in diet sodas, seems to chip away at the brain’s antioxidant defense system.”
Drug Muggers - Mineral depleting drugs
The Zoloft also depletes vitamins and minerals. 1. Adderal depletes: Vitamin B12, Vitamin C, and potassium. 2. Prozac depletes: Vitamin B1, vitamin B2, vitamin B3, vitamin B6, vitamin B12, folic acid, vitamin C, vitamin D, coenzyme Q10, calcium, magneisum, manganese, selenium, sodium, zinc, and gluatathione. 3. Paxil depletes: Vitamin B1, vitamin B2, vitamin B3, vitamin B6, vitamin B12, folic acid, vitamin C, vitamin D, coenzyme Q10, calcium, magnesium, manganese, selenium, sodium, zic, and glutathione. 4. Zoloft depletes: Vitamin B1, vitamin B2, vitamin B3, vitamin B6, vitamin B12, folic acid, vitamin C, vitamin D, coenzyme Q10, calcium, magnesium, manganese, selenium, sodium, zinc, and glutathione. 5. Celexa depletes: Vitamin B1, vitamin B2, vitamin B3, vitamin B6, vitamin B12, folic acid, vitamin C, vitamin D, coenzyme Q10, calcium, magnesium, manganese, selenium, sodium, zinc, and glutathione. 6. Wellbutrin/Zyban depletes: Vitamin B6, vitamin C, vitamin D, coenzyme Q10, and sodium 7. Remeron depletes: Vitamin B6, vitamin C, vitamin D, coenzyme Q10, and sodium. 8. Effexor depletes: Vitamin B1, vitamin B2, vitamin B3, vitamin B6, vitamin B12, folic acid, vitamin C, vitamin D, coenzyme Q10, calcium, magnesium, manganese, selenium, sodium, zinc and glutathione. 9. Risperal depletes: Vitamin A, vitamin B1, vitamin B12, biotin, folic acid, carnitine, inositol, vitamin C, vitamin D, vitamin K, and calcium. 10. Zyprexa depletes: Vitamin A, vitamin B1, vitamin B12, biotin, folic acid, carnitine, inositol, vitamin C, vitamin D, vitamin K, and calcium. 11. Seroquel depletes: Vitamin A, vitamin B1, vitamin B12, biotin, folic acid, carnitine, inositol, vitamin C, vitamin D, vitamin K, and calcium. 12. Depakote depletes: Vitamin A, vitamin B1, vitamin B2, vitamin B12, biotin, folic acid, carnitine, inositol, vitamin C, vitamin D, vitamin K, calcium, magnesium, and Essential Fatty Acids. From the book: Antidepressants, Antipsychotics and Stimulants by Dr. David W. Tanton Drug-Nutrient Depletions & Known Interactions file:///C:/Users/shops/OneDrive/Kumu%20Clinic/Kumu%20Clinic%20Forms/Prescriptions%20Deplete%20Interactions.pdf
EFT
We need to support our body's own ability to heal - all the balanced food, water, carefully monitored vitamins and minerals in the world will not be enough for most.
You need to get rid of the stresses of our past, many lurking from childhood. You need to create NEW tapes, not keep playing the old ones and repeating old habits.
You CAN change your physiology from your brain...https://www.thetappingsolution.com/free-screening/free screening-bruce.php?fbclid=IwAR389HLl6WnJqrWVdyaNOPq1GHGHB-r7VAuv2dWj1KLJxSzdWguM1RKMXs8
Stuffed emotions equal trapped negative energy. We all stuff because nobody taught us how to express or that stuffing affects our health. This trapped energy means stress. When the stress response is revving magnesium goes down iron goes up and relax, digest, heal is turned off. Our bodies have amazing capacity to heal when given the right nutrients. BUT if our stress response is revving it counteracts any efforts! EFT facilitates releasing trapped emotions from the subconscious level which we operate from 90% of the time. As a result we create an emotional environment conducive to healing :) So if you've been on RCP a while not seeing great results it's time to try EFT. Or if you've just started and want to maximize results. I offer a free 30 min consult so you can experience it right away you'll see the value. So we banish trauma, stress and limiting beliefs such a "I can't heal"
Hormone D
not a discussion of synthetic D! Thanks Jim for being an advocate for truth..I hate to see mothers giving D to babies from doctors that tell them a baby Must have supplemental D with Zero idea of exactly what d is or How the body truly works This is how I explain it to them Magnesium is the conductor of the mineral orchestra. Magnesium used to be super present in diets and in the environment (in soil and plants) So human bodies used to be flooded with magnesium and at that time, calcium may have been a deficient thing in the diet.. not now.. now the soil is depleted of magnesium and therefore so is our food. Calcium and magnesium need to be in the body's preferred ratio for physiological processes- so the body has mechanisms in place to keep calcium in ratio to magnesium. So much so that calcium has FOUR hormones that govern its balance and some scientists and doctors therefore think calcium is the more important mineral BUT these hormones all keep calcium IN RATIO to Magnesium! Most people have entirely too much calcium in their bodies compared to the levels of magnesium they have. This does not mean they have too much however.. These 4 hormones control calcium levels: -calcitonin (from thyroid gland) -parathyroid hormone (from parathyroid gland) -vitamin or (HORMONE D) active form of D: calcitriol and storage form of D- calciferol -osteocalcin (which is activated by vitamin K2) A person can have low storage vitamin D calciferol (which some call a PREhormone) which is sometimes the only test you will get. 25-hydoxy vitamin D test that's called. This is the STORAGE precursor hormone, the inactive hormone. There's a test for calcitriol, 1,25 dihydroxy vitamin D, this is the active circulating form of vitamin D and it is made using calcidiol and cholesterol. (our body absorbs an ingredient needed to synthesize vitamin D, called 7-dehydrocholesterol, from sunlight on our skin and from food sources. Our liver then converts 7-dehydrocholesterol to calcidiol) If you take vitamin D3, without knowing your free circulating calcitriol number, you could be seriously raising the amount of calcium in your body, flushing out magnesium in the process. Making the calcium to Mg ratio way out of skew. As you can see from the above hormones, too much calcium unaided by magnesium effects the thyroid, the parathyroid and the bone matrix negatively. Another important thing about magnesium.. Vitamin D from the diet or dermal synthesis from sunlight is biologically inactive; activation requires enzymatic conversion (hydroxylation) in the liver and kidney. This hydroxylation process is MAGNESIUM dependent! "Magnesium (Mg) is a cofactor that is required for the binding of vitamin-D to its transport protein. Moreover, conversion of vitamin-D by hepatic 25-hydroxylation and renal 1a-hydroxylation into the active, hormonal form 1,25-dihydroxyvitamin-D (1,25(OH)2D) is Mg dependent" Taking high doses of vitamin D without vitamin A will result in renal potassium wasting. Low potassium and high calcium will result in hypothyroidism. Low potassium to sodium ratio affects the adrenal glands and can contribute to high blood pressure. Also, low magnesium (therefore low active hormone D) can cause high blood pressure. Other vitamins, minerals /metals? Needed to help magnesium are zinc, B6, boron and bicarbonate. Zinc helps make vitamin B6. Vitamin B6 helps get magnesium into the cell. Boron also helps keep it in the cell and bicarbonate helps it work in the mitochondria. You can only achieve this balance from Foods and the best way is to juice, its natures way of supplementation Oral inputs of D will require calcium to balance serum. So if you put in D make sure there’s all the other stuff to support. You don’t want the body to take the calcium from bone to match the D in serum. A healthy natural level. The photoperiod present at conception determines the mthfr genotype to pass on. The Inuit absorb less D from diet than someone conceived in say Florida. A Floridian would not want to mirror an Inuit diet they would die from hypervitaminosis D. Liv Irene Halvorsen isn’t it interesting that way up north the sun is much less but the “food” has stored D. So much so that eating a polar bear liver can kill you from Vitamin A. It’s crazy to think our bodies aren’t savvy enough as well to store what it needs for later. In the studies the Serum level drops in fall but ramps up in winter in those who don’t start supplements. The body switches to liberation mode. It’s wicked smart.
Eczema
Eczema = Inflammation, most likely due to an allergy... The inability to CLEAR the Inflammatory process leads to the conditions we recognize as "Eczema"... http://www.eurekaselect.com/90550/article Inflammation means: o LOW Bioavailable Copper... o HIGH unbound Iron... o Increased Production of H2O2... o Challenged production of energy... The Root Cause Protocol is designed to ADDRESS ALL ^^^^ of that chaos...
EDS Ehylers Danials Syndrome
The over-riding issue w/ EDS is LACK of Bioavailable Copper that is KEY to Lysyl Oxidase Enzyme. Yes, I’m aware that there are 6 different types of EDS & that there are 🧬 genetic components to these conditions... Nonetheless, the RCP is designed to restore the Bioavailable Copper, bring Iron into proper regulation & STOP the Iron-Induced Oxidative Stress that tweaks Genes & disrupts Metabolic Pathways, mostly the ones involved w/ dura... The beauty of the RCP is that it supports the re-Building of our metabolic foundation...
Endometriosis
Kristan Kershaw: With endometriosis - the body has excess iron in tissues throughout the body - for whatever reason it positions itself in other places outside the uterus and then the excessive bleeding side of endo is the body attempting to flush. When our body senses we have more than ideal levels of 'unbound' iron - the iron we can't really use... it will store that excess iron in tissues - joints, organs (inc uterus for some! Could be the liver, brain, heart, etc for others), soft tissue etc. If there's too much of this unbound iron in the blood, then it leads to inflammation and makes us very susceptible to getting infections, parasites etc.... so the body always aiming to avoid that sort of thing, it stashes it away. To make the iron 'bioavailable' and not this unbound type... we need a protein called ferroxidase - it's part of what we test for in 'ceruloplasmin'. We need ferroxidase to serve many purposes in the body including moving bioavailable copper AND iron around, being an anti-inflammatory protein and helping the body to do so much more in the enzymes and day to day metabolic function. When we are under stress, magnesium is lost, and this ceruloplasmin has to get to work more and more to reduce inflammation around the body. The bioavailable copper (and then bioavailable iron with it - they go together)........... drops in that process and we see the parameters more and more of 'low iron' as well as inflammatory situations like food intolerances, hormonal imbalances and so much more. The other angle to endo is that hormonal side - when we have all the minerals in check, we make a certain combination of the hormones. The more stress our body is under (perceived stress from emotions, physical stress and everywhere in between)... we put our adrenal glands under pressure. They also make the precursors to our hormones. When the adrenals get to a certain point where they cannot make the right balance of hormones due to the mineral imbalances, then the ovaries will kick in and do what they can do to help. It's the body going into numerous backup plans along the way to aim towards balance. The Root Cause Protocol is designed to support the building blocks upwards so that our adrenals can recover, our hormones are made in balance, we can respond to stress in better ways and not be running on empty all the time with rampant inflammation. It also helps with things like better digestion so that what we eat is better utilised, gives us freedom to not fear reactions from foods and so much more. Teresa Bowley Morley Robbins This article is saying there is iron overload in the pelvic cavity, which makes sense because there is excessive cell proliferation, and inadequate cell death in the endometrium. There are literally too many red blood cells located there. This does not imply an iron overload systemically. However, it makes sense that such patients would benefit from excision surgery. Morley Robbins: In a body that has LOW Bioavailable Copper -- that would be virtually ALL folks on this Planet -- the body is designed to STORE Iron in the Liver, 1st & Foremost... As the assault of excess, unbound Iron -- in our diet, our supplements, our water continues to BUILD -- the body then STORES Iron in Tissues ALL OVER -- it's just that the Research doesn't always put the Spotlight on that pervasive response... I've read ~1,000 articles on Copper, Iron, & CopperIron Metabolism over the past 9 years. And when you dig DEEPER, you will discover that the LOW Copper/HIGH Iron (in the Tissue) concentration is PERVASIVE in the body... It's also important to understand that Iron ACTIVATES & FOSTERS cell proliferation of Stem Cells... Iron is ALSO the CAUSATIVE agent in Growth Factors that are prevalent in Cancer... Iron is ALSO the CAUSE of Inflammation (Iron activates NLRP3, Nagamura et al, 2015). I'm thrilled that you've read about this issue as it relates to the Uterus. I can assure that this IRON-ic dynamic is happening elsewhere in the body. You need only LOOK FOR IT... A votre sante! Mandy Chadwick: So many ladies have endometriosis and bleed heavily to the point of utter debilitation. In many cases sadly a result of taking iron in pregnancy or, like many (me included) iron supplements in teenage years. PCOS, endometriosis, heavy bleeding, thinning hair, fatigue? Hysterectomy is often offered as a solution as it was to me. (I refused and pushed through). The issue is inflammation of iron. I also had weak ceruloplasmin. How iron affects hormones, oestrogen and women at menopause https://www.ncbi.nlm.nih.gov/.../pdf/ars.2009.2576.pdf Mandy Chadwick For ladies who are feeling anxious and possible hysterectomy please read this. I would like to encourage ladies to understand why they are suffering those debilitating symptoms of heavy monthly blood loss and pain. Morley has taught us so much about inflammation of iron leading to these debilitating symptoms. I suffered and managed to overcome this. Hope this will help someone to make a wise informed choice. http://wisewomanwayofbirth.com/your-uterus-keep-it-for-life/ Morley Robbins - MAG-pie and MAG-net ALERT! For those who are or know someone who is struggling with Endometriosis, please read slooooooowly the LAST sentences of BOTH the "RESULTS" and the "CONCLUSIONS" Sections: http://www.ncbi.nlm.nih.gov/pubmed/22771029 For those that prefer to read the FULL Monty: http://www.fertstert.org/arti…/S0015-0282%2812%2900656-5/pdf This AIN'T no medical disease, folks... Regrettably it IS a classic case of metabolic dysfunction CAUSED by mineral dysregulation, courtesy of Excess, Unmanaged Iron, largely due to a toxic food & supplement industry, couple with an anemic ability to properly interpret Iron blood tests by M.ineral D.enialists ALL over the Globe... How is our "gaggle" of MAG-pies doing on connecting the dots of the metallic ORIGIN of ALL chronic disease?!?... Iron-ic, eh?.... A votre sante! https://www.facebook.com/groups/MagnesiumAdvocacy/permalink/960603950674341/
Estrogen imbalance
Estrogen imbalance is masking iron toxicity. Hormone dysregulation (estrogen) = iron toxicity premenopausal, perimenopausal, or menopausal = iron is building at a rapid rate Estrogen's going down, iron's rising because a women who's no longer cycling has no way to make deposits, right. Well, it turns out that the mechanism to break down the bone matrix is called acid phosphatase.And acid phosphatase is activated by iron. when estrogen is rising it is because there is no ferroxidase enzyme function or there's limited ferroxidase when ferroxidase is low, the body goes to "plan B" and employs estrogen estrogen detoxifies through the liver and is magnesium deficient - a diet high in fiber can help to move estrogen out of the body. Also, the herb vitex is amazing for balancing hormones, whether too low or too high. LOW Iron in the Blood typically means HIGH Iron in the Tissues... Your symptoms (Lyme, COMT++, High Estrogen, etc) are ALL signs of Excess, Unbound Iron. Your bloodwork is NOT being interpreted completely. Hormone Dysregulation and Unchecked Pathogens (they ALL live on Iron!) are simply FURTHER signs of CopperIron Dysregulation...
EMF
"EMFs are a “silent” Stressor that trigger a Histamine response. Histamines cause Electrolyte derangement, resulting the LOSS of Mg which results in loss of Potassium, an influx of Ca++ & Na++ & a LOSS of Energy in the Cells. (-65mV >> -30mV) Histamines are degraded by two enzymes, DAO & HNMT, that are both dependent on Mg, B6 & Bioavailable Copper. Those THREE nutrients are in short supply in an Iron TOXIC body... Histamines are NOT promoted by Iron, but the lack of Mg & Cu is especially challenging in a body with too much Iron. In effect, that Iron becomes an “Antenna” for those EMFs... Make sense?!?"" Consales et al, 2012, “Electromagnetic Fields, Oxidative Stress, and Neurodegeneration” https://www.hindawi.com/journals/ijcb/2012/683897/citations/ Please note that the 1st study noted ^^^^ (Maaroufi et al, 2014) is a very provocative one that chose to combine EMFs (900 MHz) with Iron loading on the experimental rodents… The sentence that REALLY caught my “eye,” (pardon the pun…) was the following: “A link between EMF, iron accumulation in the brain and neurodegenerative disorders including Parkinson’s and Alzheimer’s diseases has been suggested.”
Excessive LEAD
The effects of lead on the nervous system have implicated it as a major contributor to hyperactivity, learning disabilities, behavioral disorders, attention deficit, seizures and decreased IQ. Reports have implicated lead in the Sudden Infant Death Syndrome (SIDS). It was found that the incidence of SIDS followed increased air levels of lead by one or two months. Tissue studies of infants who died of SIDS revealed higher lead concentrations than those who died of other causes. Lead displaces calcium and is deposited in bone through the ends or joints. Lead can destroy the normal cartilage tissue and contribute to arthritis. Since the teeth are similar to bone, lead exposure can increase the formation of dental caries in children.
Fatigue
Fatigue Not having enough bioavailable copper and retinol (+ excess STRESS) leads to excess unbound iron in our body. If we have sufficient bioavailable copper, we will be able to make the iron "bioavailable" too! The body then doesn't respond with inflammation and lack of energy, as it does when iron is in other "unusable" forms!
Fast Oxidizer
Fast oxidizer is vulnerable are three areas it will lose, it will lose calcium and magnesium under stress
Fermented Cod Liver Oil
WAPF vs PP FLCO/CLO history Daniel Corrigan Olga Fadeeva Prior to starting the Weston A Price Foundation in 1999, Sally Fallon was a board member of the Price Pottenger Nutrition Foundation. Price Pottenger (previously known as the Weston Price Memorial Foundation). Price Pottenger started in 1952 and they own all of Dr. Price's work (notes, manuscripts, studies, etc). While at Price Pottenger (PP), Sally Fallon coauthored the book "Nourishing Traditions" along with Patricia Connolly. Pat was the PP curator and had learned everything about Price's work from Alfreda Rooke (the previous curator). Alfreda worked directly with Dr. Price. The original edition of Nourishing Traditions featured Patricia Connolly on the cover, as a coauthor. It also had a section of the book about Price Pottenger Nutrition Foundation. However, once Sally quit Price Pottenger, she removed Patricia Connolly from the cover, and deleted the section on PP ... and replaced it with a section promoting Sally's newly created organization, Weston A Price Foundation. I served on the leadership team of the very first WAPF local chapter (about 18 years ago). I was part of WAPF for a number of years before I heard about Price Pottenger. Over the years, Sally has strayed from Dr. Price's teachings. One example is cod liver oil. In the original edition of Nourishing Traditions, the section on cod liver oil talks about how important it is to buy a cod liver oil with added antioxidants and to store in the refrigerator. Sally later updated that section to promote fermented cod liver oil (FCLO) - which was never recommended by Price. (I've seen Sally promote FCLO as something that Dr Price recommended). In Nourishing Traditions, Sally also claims that FCLO contains 10,000 IU of vitamin A per teaspoon. Interestingly, WAPF didn't test FCLO until 2015 and found that FCLO only has about 3,000 IU / tsp of vitamin A. The WAPF website still lists FCLO as having about 10,000 IU / tsp (even after their own testing showed otherwise). Basically, Dr. Price never recommended FCLO and it doesn't have 2 or 3 times the vitamins of "regular" cod liver oil. Sally also insists that grains must be "properly prepared" in the "traditional" method. Which means soaking or sprouting, as a means to reduce the dreaded "anti-nutrient" phytic acid. Besides one of the tribes making sourdough bread, this was not a major finding of Dr. Price. All of the WAPF people that I know (and I used to think this way too) believe that all of the cultures that Price studied were soaking their grains and nuts. In reality, the key takeaway from Dr. Price was that grains should be ground into flour immediately before using. I'll post a couple of relevant links below. https://www.thefamilythathealstogether.com/weston-price.../ https://price-pottenger.org/.../cod-liver-oil-historical... https://www.facebook.com/cheeseslave/videos/10153979098461304/?hc_location=ufi http://www.cheeseslave.com/fermented-cod-liver-oil-scandal-an-open-letter-to-sally-fallon-morell/?fbclid=IwAR1qzEXQK4E6b91Od6fNdGq_gnpNlXbhwYB4oXnQZoHBttjWvaA8kTFxScI http://drkaayladaniel.com/fermented-cod-liver-oil.../ http://www.davidgumpert.com/more-upheaval-at-wapf-as. Rancid oil consumption implications Rancid oils may produce damaging chemicals and substances that may not make you immediately ill, but can cause harm over time. Chemicals such as peroxides and aldehydes can damage cells and contribute to atherosclerosis. Free radicals produced by rancid oil can also damage DNA in cells. Produced by toxins as well as by normal bodily processes, free radicals can cause damage to arteries as well act as carcinogens, substances that can cause cancer. https://www.quora.com/What-are-the-health-implications-of-consuming-rancid-oil What’s wrong with eating rancid oils? “There are at least two (problems),” lipid specialist and University of Massachusetts professor Eric Decker told Eng. “One is that they lose their vitamins, but they also can develop potentially toxic compounds” that have been linked to advanced aging, neurological disorders, heart disease and cancer. https://californiaoliveranch.com/rancid-olive-oil-may-be-hazardous-to-your-health-experts-suggest/ Integrative medicine specialist Andrew Weil said: “They’re carcinogenic, pro-inflammatory and very toxic. … They are also widespread in the food chain.” Fish oil has omega-3 fatty acids, EPA and DHA. The recommended cod liver oil has omega-3 fatty acids, EPA and DHA plus vitamins A and D. Admin - RCPC
Ferritin
Iron is leaving the ferritin before the ferritin molecule shows up in the blood. And what causes ferritin to lose iron is called hydrogen peroxide. People are flooded with hydrogen peroxide because of 1. high sugar diet 2. hi vitamin D diet 3. any other number of factors Cause an increase of hydrogen peroxide in the body. (Most enzyme functions are copper dependent. With low copper, histamine levels can be high- likely if sleep is affected as histamine uses up melanin which is needed for melatonin. Less is often more when it comes to situation like this one. Slow and low is recommended approach.)
Ferroxidase (FOX) -
FERROXIDASE KEEPS THE IRON MOVING – IN CIRCULATION Iron is meant to be in circulation. Iron is meant to be in constant movement around the body and it's made possible by ferroxidase enzyme function. There's ferroxidase enzyme function all over the body. It's not just the liver. The liver's the most notable. Ceruloplasmin (Cp) - Considered the MASTER “Multi-Copper Protein.” Cp has an “active” & “inactive” state, or an “enzyme activity” & “immunoreactive protein” state. In its “active” state, Cp contains up to 8 Copper atoms surrounding a molecule of Oxygen (O2). But unfortunately, only the “inactive” state is measured by commercial labs using the Serum Ceruloplasmin blood test; there are no commercial labs that measure the “active” state. (See Ideal Lab Values here…) This protein was discovered in the early 1940s by Swedish Physiologists, Carl G.Holmberg & C.B. Laurell, and first described in their article published in 1947. Ferroxidase (FOX) - The “active” (or “enzyme”) form of Ceruloplasmin. FOX regulates Iron and prevents it from causing Oxidative Stress, (aka. rust). FOX is the MASTER antioxidant enzyme in the human body. Ferroxidase has the highest amount of activity in the Liver and the Brain; and has notable activity in the Intestine (called Hephaestin) and in the Placenta (called Zyklopen). Without optimal Ferroxidase enzyme activity, Iron starts to build in our tissues, especially our Liver cells and Endocrine glands. As we age, this chronic build-up of Iron leads to decreased energy production in the cells, and increased Inflammation in our tissues and organs. How do we increase the amount of Ceruloplasmin (Cp) protein and the activity of Ferroxidase (FOX) enzyme? This is THE PRIORITY focus of the steps in The Root Cause Protocol. By increasing Cp & FOX, we decrease Iron dysfunction, and we stop the chronic loss of Magnesium.
Ferroportin -
A copper-dependant protein that acts as the “doorman” and allows Iron to exit the cell. It is facilitated by Ferroxidase, and blocked by Hepcidin.
Fibrin
Neprinol is a proprietary combination of nattokinase serrapeptase, rutin, amla and other proteolytic enzymes specifically formulated to assist and defend your body from the damaging effects of fibrin. As fibrin builds up in our bodies, it may cause many unhealthy conditions.
Flat feet
would beweak adrenals, which would be from a lack of bioavailable copper in the vitaminC s wife has been doing chiropractor for 38 years. She has healed dozens of clients of scoliosis with just chiropractic alone because she knows that the issue, it's a signaling issue as well. There's many ways to solve this problems. I'm sure there are acupunctures who've solved scoliosis with acupuncture. Again, as a mineralist, what I'm looking for is how do we ensure proper signaling and proper energy production, and a body that's under stress is going to begin to create curvature of the spine or flat feet because certain enzymes aren't being fed properly. There's just different pathways of explaining what the dynamic is.
Flouride
Morley Robbins: it’s a very destructive molecule & it LOVES to steal electrons & disrupt the other halogens. Let’s stay away from the ‘conspiracy theory’ side of things of which there is a lot to and just focus on the biochemical aspect. It is the most ACIDIC element on the planet, and Mg is the most ALKALINE, so when you put fluoride in, you change the bioavailability of Mg. There is no biochemical pathway in the body that requires Fl and no enzymes need it to function
Food Sources of Iron
Gall Bladder Issues
Toni Little The whole RCP will help a lot but the wholefood Vit C is particularly important, also choline is very useful for the gallbladder and helps in the break down of fats. I did training with Morley and he has said anyone with gallbladder or breaking down fat issues should take it. I don't know what brand he would recommend but i got Jarrows Citicoline CDP Choline it is 250 mg and I take one a day with food. If you have an issue twice a day is recommended. The whole protocol will be a benefit but if you cannot get her to start now just get her to do whole food vit C and choline. Hopefully it will help enough she is happy to do the Protocol. All issues start with low Mg and bioavailable copper and iron in tissue the protocol addresses these things. Patrick Boyle (RCP Consultant): Toni Little is spot on. All 'itis' issues are inflammation. Autoimmune is a fancy word for toxic iron overload and low bioavailable copper. Fat digestion requires many things, magnesium is one of them. When the body is under chronic stress (inflammation), minerals like magnesium are LOST, rather quickly. My bet is that iron has taken up residence in her organs, like everyone else, and is creating oxidative stress, or, inflammation. The immune system will respond but will bring in iron in that process. If iron is not bound (via bioavailable copper and it's transport mechanisms of ceruloplasmin), it is adding fire to the flames. Hence, autoimmune.... the immune system is inadvertently causing more 'itis' because it doesn't have what it needs to be effective. Get the copper bound, making it bioavailabe, and it will get iron back in line and behaving as it should. You will find the 'autoimmune' issue will resolve and health is returned. That's what this entire RCP is all about, balance and proper bodily function. Also note, when copper is missing from the enzymatic functions that require it, bile will get sluggish as copper enzymes are required for that organ to function optimally
Gastric Ulcers
Aloe Vera Juice: It's a nutritional powerhouse and particularly well indicated for gastric ulcer situations from what I've read (used in horses and humans!) so it may be worth considering - that's all I was suggesting above.
Gene Expression
Morley - It might be a KEY piece of the puzzle... Please know, Pasteur MADE SURE that we OBSESS over the Pathogens and the Booga-wooga Bugs... It is a SOCIAL MEME. Unfortunately, it is just a STORY, NOT the TRUTH... So the WHOLE "Germ Theory" is BOGUS... And imho, the WHOLE "Gene Theory" is NOT far behind... Genes RESPOND to their EPI-Genetic Environment... Are they "Broken" or are they "Hungry?" It is a debatable point, I assure you... And what do ALL Pathogens need to exist, replicate and THRIVE?... Excess, Unbound Iron... which is the RESULT of a systemic LACK of Bioavailable Copper and Retinol-A... And Retinol-A combined with Copper play a very POWERFUL role in proper gene expression...
Genetics
all these gene defects that we're being pummeled with are caused by a lack of bioavailable copper. Because anytime you see the word monooxygenase, it means it requires copper. The enzyme doesn't work without copper. "I believe that all of these snips are functional metabolic dysfunction. They are not genetic defects."
Glutathione -
A particularly important protein for lowering Oxidative Stress (aka. “rust”). Glutathione binds Copper which prevents it from becoming “reactive” inside the cells. Glutathione also plays a critical role inside the cell, transporting Copper to ensure proper distribution to critical proteins and enzymes. Glutathione’s "copper top battery" is Glutathione Peroxidase, enabling it to be reused over and over. Glutathione Peroxidase is vital because it turns 2 molecules of H2O2 (Hydrogen Peroxide) into 2 molecules of H2O (Water) and one molecule of O2 (Oxygen). Synthesis of Glutathione involves two metabolic steps that require Magnesium.
Grey Hair
Lynn Holladay Avery - It's a complex biological process centered around a lack of bioavailable copper that results in incomplete breakdown of oxygen into water and ADP. You end up with hydrogen peroxide, which reacts with unbound iron and basically creates rust. The Root Cause Protocol (RCP) addresses these issues and more. RCP Consultant Dale Morley: Just to add to Lynn's comment above, maintaining hair colour requires tyrosinase. Tyrosinase is reduced as a direct result of the hydrogen peroxide which results in hydroxyl radicals breaking it down. The body usually keep H2O2 in check by catalase but as the body ages & we become BIOAVAILABLE-copper deficient due to excess, unbound iron there is less catalase. The reason why COPPER plays a key role in creating pigment in hair is by allowing the production of tyrosinase as copper is ESSENTIAL to tyrosinase production. Copper oxidizes it in melanin which colours the hair. The RCP addresses this. Liv Irene Halvorsen. Tyrosinase is found in whole food vitamin C which is mainly stored in our adrenals.. vitamin C also has bioavailable copper.. Make sure you increase your Ceruloplasmin production by starting all the steps on The Root Cause Protocol.
GI distress
The aloe juice may still be ok if it's just as is with no additives on the 'stop' list. It can help the stomach side of things 😊 Digestive enzymes with food would be worth looking at - trienza or the like. Probably would help the whole c tolerance too...
Gut Dysbiosis
Lining of digestive tract (enterocyctes=food enters cell) food broken down in the cell for transport. Iron from food needs to go from ferrous to ferric and ferroxidase enzyme. Stressed out and exposed to known agents for copper Dysregulation - ferroxidase goes south and the iron can’t get out of the enterocyctes. BECOMES attractive platform for bacterial overgrowth.
Hair Loss
Liv Irene Halvorsen There can be many reasons as to why we are losing hair. One of them can be Vitamin C deficiency. Lacking vitamin C may play a role in dry and breaking hair and rough skin as well. Along with other nutrients, vitamin C can help support hair growth by assisting with collagen production and with the absorption of non-heme iron. Because this is a water-soluble vitamin, your body cannot store it since it is washed out via the digestion/food storage processes, so you must replenish it daily via your diet. B-complex deficiency may cause dizziness and fatigue as well as hair loss and weak brittle hair. B vitamins, particularly biotin (B7), may support hair growth. Vitamin E is a fat-soluble vitamin and a potent antioxidant that helps prevent damage to cells and tissues caused by free radicals. As well as participating in the formation of red blood cells, vitamin E also helps your body metabolize vitamin K and contributes to keeping your immune system strong. This vitamin helps support hair growth by promoting good circulation in the scalp and helping transport oxygen and other nutrients to the hair follicles. Vitamin A supports hair growth by helping to keep the skin scalp in healthy condition. Since most of us is lacking vitamin A many people will have a feeling hair grows faster implementing this into our daily routine. Another thing is looking into how much sulfur and silica we are using in the diet. Look into your diet and how the balance between the minerals are as most people that is losing hair have unbalanced minerals. Excerpt from http://www.autismhelpforyou.com/Diabetes...%20Iron...) - Let us also remember that one of the mechanisms the body had for riding itself of iron and/or other toxins (i.e., mercury, etc.) had to do with HAIR! Iron was absolutely a toxin when found in excess. Could it be that too much iron was leading to hair loss and/or damage - as in the ear for example - and that this somehow played a role in "deafness" now being associated with diabetes! Certainly, just looking at a chemotherapy patient told us that hair had something to do with the immune system. Persons undergoing chemo usually lost all their hair - but then, it grew back. Was that because toxins in chemotherapy killed the hairs? Studies were also starting to indicate that iron overload could result in hair loss (i.e., balding in men having hemochromatosis). Thus, clearly, iron and hair were also tied to one another as were insulin and hair - not surprising of course given that iron and insulin modulated one another! Thus, if "hair loss" was associated with excess iron, could atrophy of hair in say the Organ of Corti (in the ear) also be associated not only with insulin but excess iron levels - perhaps from prenatal vitamins while the infant was still in the womb. It certainly seemed to me that hearing impairment in 1 of 300 children serious enough to cause language delays and learning disabilities and 1 in 1,000 children being born deaf was a rather high percentage! Again, note that "deafness" was very much associated with damage to or loss of hairs in the Organ of Corti (in the ear) - and once those hairs were destroyed - it was believed they did not "grow back" and as such - hearing impairment or deafness was permanent! Was "hair loss or impairment" due to iron overload also at play in problems with "touch" in children with autism? What about hair in the digestive tract? Just what exactly were the impacts of iron on hairs found throughout the body? A study I had found on iron and the issue of iron supplementation in women during gestation clearly indicated that studies looking at the impact of iron supplementation during pregnancy were virtually non-existent (see Book 3 bibliography - search for iron supplementation). Again, for much more on all this, I strongly encouraged you to read "Book 3", a book I had entitled "Breaking The Code: Putting The Pieces In Place! - posted in full on this website!
Hashimotos
Morley on Thyroid We need to STOP this "Thyroid causes ALL Problems MADNESS!!!" CopperIron Dysregulation creates outrageous levels of Oxidative Stress that affect the metabolism of the Body & Brain & THAT then CAUSES: o Thyroid dysregulation, MOST OF WHICH occurs in the LIVER! o PCOS... o Hormone Dysregulation-- AGAIN occurring in the LIVER! o AND HUNDREDS OF OTHER AFFLICTIONS!... And unlike STTM, we REJECT: o Hormone-D! o Ascorbic Acid (it kills Ferroxidase!) o Iron Supplementation (that is metabolic POISON) o to name but a few points where we SEE the problem differently... I would encourage you to read up on the truth of Iron Toxicity noted in the 62 Posts on Iron Toxicity. And I would ALSO ask you -- and OTHERS -- to STOP pushing the beLIEf that the Thyroid runs the body... We KNOW better on the MAG FB Group! Valerie Engh - Hashimotos is a symptom of non-functional toxic iron overload in the liver. When the liver is congested with non-functional iron it slows down the conversion of T4 to T3. Follow the Root Cause Protocol which includes taking the adrenal cocktails which are required to replenish the mineral depleted adrenal glands. Lower the non-functional toxic iron in the liver and then the thyroid hormones will be able to be converted properly in the liver. The Root Cause Protocol also increases Magnesium RBC which is needed to regulate Calcitonin, PTH and Hormone D which regulate the level and the placement of calcium in the body. The Root Cause Protocol is also designed to increase our Ceruloplasmin ferroxidase enzyme (bioavailable copper). The Ceruloplasmin ferroxidase enzyme is required to make the unbound iron (which has been removed from the blood and stored in our tissues and organs) functional and circulating throughout the body to where it is needed –moderator Patrick Boyle (RCP Consultant) When your iron and copper are out of balance, you will have a thyroid issue, in part because iron is highly oxidative (STRESS) and will overwhelm your adrenals (responsible to controlling stress). In the case of Hashimoto's, it's a little more complex. Hashimoto's: In Dr. Brownsteins book on iodine, he simply states that the thyroid converts Iodide to Iodine and when the H2O2 used to do this conversion isn't controlled, you are left with Hashimoto's Thyroiditis. If you look deeper for the root cause you will find that when the thyroid converts Iodide to Iodine by using H2O2, the body needs to break down the H2O2 back into water and oxygen when it's done. If this cannot happen, the hydrogen peroxide 'irritates' the thyroid gland tissues to a point it gets inflamed ("itis" means inflammation). Catalase is a copper dependent enzyme that converts H2O2 back to oxygen and water. If your ironcopper regulation is not balanced due to iron toxicity, low retinol, lack of bio-available copper etc... Catalase is not available to do it's job. As the thyroid gets inflamed, the body reacts by processes that actually bring iron to the damaged tissue (its part of your immune response). In Jym Moon's book (Iron: The Most Toxic Metal), he makes it very clear that iron has an affinity for and is drawn too, damaged tissue. If that iron isn't bound (controlled by bio-available copper bound to ceruloplasmin), the iron showing up is actually causing more problems because it's not behaving as it should. It's a bull in a china shop. As your body is activating your immune system to deal with the inflammation, it is also unwillingly being the cause of more inflammation. This is then labeled an 'autoimmune' disorder when in fact it's a copperiron dysregulation issue. You have to have your copper and ceruloplasmin working properly in order to make the iron in the body behave as nature intended it to. This is a simple and brief explanation without getting deep into some of the processes, enzymatic functions and chemical breakdowns. BTW, the reason doctors give you the thyroid meds and your antibodies go back down is that you are basically stopping the thyroid from doing it's job and the "itis" starts to calm down as a result of being on vacation.
Heart Attack
Folks: The BEST Predictors of Heart Events: o LOW Mg RBCS: ~ 5.5 or BELOW... o HIGH Unbound Iron found with UBER low Ceruloplasmin ( 250 Mg/dL) Cholesterol levels are ENTIRELY REGULATED by these TWO minerals via their OPPOSING reactions on the rate-limiting enzyme: HMG CoA Reductase. FOCUS on the minerals & the mineral-activated enzyme will take good care of you!...
Heartbeat - Pounding, Racing, Irregular
Morley Robbins "What differences in the Heart Beat REALLY mean… Pounding Heart Beat => TOO MUCH Calcium..(from a lack of Mg) Racing Heart Beat => TOO MUCH Sodium…(from excess Iron in the Heart that CAUSES a LOSS of Maggie & then Potassium, and a RISE in Sodium due to the lack of Mg and K…) Irregular Heart Beat => TOO LITTLE Potassium…(most likely from TOO MUCH Synthetic Hormone-D, because the “Vitamin -D blood test showed LOW, but it was ACTUALLY from TOO LITTLE Maggie” and Iron has a wicked affect on Potassium status,as well…) ALL Heart issues come back to Magnesium...and what I am learning with increasing facility and fervor is that Iron Overload (excess, mismanaged Iron due to a lack of Ceruloplasmin) is at the BASE OF ALL THIS INSANITY…
Heart Disease, Periodontal Disease, and Osteoporosis
Heart Disease, Periodontal Disease, and Osteoporosis are all related to low bioavailable copper being around to allow for the appropriate recycling, recovering, and healing of these three areas And, likely in the presence of one, assume the presence of the other two. (Current or eventual) Kristan Kershaw: The genetic 'pre-disposition' to heart disease is just as much telling you that your family have mineral dysregulation, as it is telling you that your genes themselves may make you more prone to having heart disease. Underlying heart disease IS mineral dysregulation - excess unbound iron, insufficient bioavailable copper, magnesium and stressed out adrenals. The genes may make you more "prone" to this when your body is stressed from any angle - especially from minerals, but nobody will get heart disease purely because they have certain genes.
Heme
A prevalent protein throughout the body that has Iron at its core. If you can’t make heme, the body isn’t going to function properly. Four Heme are “knit” together to create Hemoglobin.
Hemoglobin -
The protein responsible for transporting Oxygen. Also, from 1862 - 1972, it was the most typical blood measurement of Iron status. But it’s not a particularly useful measurement as this is the “dipstick” way of measuring Iron -- it’s like measuring the amount of oil in your car, but what we should really be measuring is Serum Iron, which is like measuring Miles Per Gallon.
Things that lower Hgb:
o lack of Magnesium...
o lack of Bioavailable Copper...
o lack of Mg & Cu CAUSES RBC Lifespan to drop from 120 days >> 20 days (80% DROP!), which INCREASES rate of Hemolysis, which accelerates RBC T/O...
o lack of B-Vitamins, esp. B9 & B12 (BOTH are Cu Dependent, despite the Internet BS!)
o lack of Catalase, which is Energy & Copper Dependent (Catalase KILLS H2O2 in RBC!)
o too much Sugar in Diet >> H2O2!
o too much Homocysteine >> H2O2!
o too much Histamine >> H2O2!
For my tougher cases, I have them using Suzy Cohen, RPh’s Catalase & Bernard Jensen’s Chlorophyll...
The LAST thing I would ever consider is Mo’ Iron!...
The offending agent with low Hgb is more likely to do with H2O2 (hydrogen peroxide) build-up than “too little iron”.
The presence of catalase is what dictates the bioavailability of Hgb because your body can’t make Hgb if it can’t make catalase. You can’t make catalase if you can’t make heme, and to make heme you need bioavailable copper. Supplementing with Catalase (Suzy Cohen) can also help to get over the H2O2 hump.
Retinol is important for Hgb production also, so I would try eating beef liver (as opposed to taking capsules), increasing CLO to a tablespoon per day, bee pollen, and PLENTY of wholefood Vit C.
Other things helpful to raise Hgb are; chlorophyll (Bernard Jensen Alfalfa) – helps to clean up H2O2, near infrared (NIR) light if you have access to it, red beets & carrots, buckwheat powder or uncooked buckwheat with kefir left overnight & consumed the next morning. IP6 & lactoferrin are goof natural chelators so I would take those too.
• Heme – porferin ring with Fe in centre. Knitting 4 heme into Hgb needs BioA Cu.
• Chlorphyll - With Mg in centre.
• Chlorophyllin - With C in centre.
Moving too fast to clear H2O2 can cause a Herx reaction.
Increasing dietary iron, sugars, & omega 6 oils can lead to increased production of H2O2.
70% of the body’s Fe is complexed in Hgb - so Hgb is the “engine”. 10% is complexed in ferritin – “the trunk”. Myoglobin carries 10% in muscle cells, and other 20% is found in different Fe-S clusters and heme-based protein. You have to make catalase in order to make
hemoglobin. If the body can't make catalase, then it can't make hemoglobin
because it knows it needs energy and it needs the ability to neutralize hydrogen
peroxide in order to allow hemoglobin to get to the right level. people are being trained to think that they need more iron to make
hemoglobin. Trust me, I get that hemoglobin has four heme and that there's an
iron in the center of the heme, but that's usually not the problem. It's the
hydrogen peroxide that's in the system because of too much vitamin D, too
much ascorbic acid, too much sugar in the diet are the big three that causes a
massive rise of hydrogen peroxide. What I'm coming to realize is that hydrogen
peroxide is in fact what not only ages us, it's what kills us. It's the peroxidation
of the tissue, and that is a very significant form of oxidative stress.
Hemosiderin -
An Iron storage "complex" found primarily inside of the Macrophage cells, as opposed to circulating in the blood. If the body cannot make adequate levels of Ferroxidase in order to load Iron into Ferritin, the body is forced to store the excess Iron in Hemosiderin. It is NOT routinely measured in humans, which leaves us in the dark about how prevalent and significant Hemosiderin levels are as a source of excess, unbound Iron.
Hemoglobin in pregnancy
Morley on Hemoglobin in Pregnancy Morley's take on this... "Hemoglobin in a pregnant women — esp. in the 2nd half of the pregnancy — is SUPPOSED to DROP to 8.5-9.5 mg/L… Please re-read those numbers ^^^^, AGAIN… This is a CRITICALLY important fact and set of studies that challenges the conventional clinical paradigm of where Iron levels are supposed to be during the course of a HEALTHY pregnancy… Again, what they found is that as Hemoglobin DROPS, birth weight of the infant RISES… HIGH Hgb is a sign of potential Pre-mature birth and pregnancy risk…" http://gotmag.org/post-43-on-iron-toxicity-the-gestation.../ Manage gotmag.org Post #43 on Iron Toxicity: The “gestation & birth” of… Bee pollen or nutritional yeast for B's is recommended per the protocol. [ Low Hb in pregnancy. From Morley. Before commenting on your notable numbers, can you provide some answers to these questions?... o Prior to your pregnancy, did you have any health issues or mineral imbalances that you were aware of?... o Is this your 1st Pregnancy, or have there been others?... o In addition to the supplements that you noted, have you been taking any Prenatals?... o What was your Hemoglobin at the START of your Pregnancy, and PRIOR to your pregnancy?... The process of Hemodilution LOWERS the Hgb, and yours is very much in alignment with the Research of 150,000 Live Births by Philip Steer, MD who found that the healthiest babies were born to Mom's who's Hgb was between 8.5-9.5 (Steer, 1995) which is well below the norms in the world of conventional OB today... And here's a more recent study that CLEARLY indicates the Ferritin levels are INVERSELY correlated with the weight of the baby and the LAST SENTENCE of this Abstract needs to be factored in VERY carefully: https://academic.oup.com/humrep/article/15/8/1843/670873 MORE Iron is NOT always the answer... I'd welcome your answers to those questions before commenting further... "A" votre sante!]
Hepcidin -
Regarded as the “Iron Hormone”, it’s also known as the “Inflammation Hormone.” Hepcidin acts as a key cellular agent -- it allows Iron to be absorbed & released in the Enterocytes and then put into the circulatory system. When there is too little Iron, Hepcidin prevents Iron from exiting the Enterocyte. Hepcidin also allows Iron to be released from the Macrophages. Low Hepcidin is not necessarily an indication that the body is deficient in Iron.
Hephaestin -
Similar to Ferroportin, the “doorman” in our gut that allows Iron to be released from the cell into the circulatory system. When this “doorman” is properly loaded with Bioavailable Copper, it works correctly, and Iron can exit the cell and complete its Circulation around the body. When Copper is NOT Bioavailable, Iron builds up in the cells/tissue, which generates Oxidative Stress.
Hereditary hemochromatosis
In the Dietary Reference Intakes (DRIs 2001), the Food and Nutrition Board acknowledged an increased risk for hepatocellular carcinoma in individuals with hereditary hemochromatosis(Iron—The Most Toxic Metal 18)
Histamine/Histadine
Lower MAG level increased sensitivity to environment Lower Bioavailable copper = increased sensitivity to environment low MAG in combo with w/ low bioavailable copper = more mast cells produced enzymes breakdown histamines (DAO and HNMT) NEED MAG, Bioavailable Copper, and B6 to make those enzymes work. IF enzymes don't work, the histamines will wear you out - becoming a stressor, then becoming a histamines intolerance, leading to perpetual loss of MAG and potassium inside the cell as a perpetual state of being flooded with calcium and sodium, where it's supposed to be outside the cells, it's going inside the cell. histamines are used to respond to environment mast cell house histamines Abundance of mast cells which have an abundance of histamines Increase of mast cells in MAG and Copper deficient organisms. Mast cells MAG deficiency, mast cells COPPER deficiency. Mast cell issues coming from tissues that have been subjected to notable stress. The precursor to histamine is histidine... it needs B12, B6, copper and whole food vitamin C, Underlying histamine response, is the body staying in fight-flight and needing bioavailable copper, mag and b vitamins to make our own antihistamines. Catalase, histablock etc can absolutely help, but how much to use (of the latter especially) etc I think varies depending on the individual and what’s going on. I see it as a first-aid helper rather than a solution to rely on all the time. Histamines aren’t the main, though at times they end up more discussed than others. The stress that underpins the histamines is still common to the other ‘blocks’ that people experience too... - the need for EFT or the like to reduce the body sitting in fight-flight from past (& present!) triggers - the need to get iron out of the body once it’s been stimulated out of storage - the need to get rid of the grip on allopathic labels (which I would hope for a trainee of a morley would be gone, but for a child his age, maybe he still thinks he’s broken?? Do you have a similar fear that you can’t shake?.... see item #1) - one more I’m blanking on right now. If these are active OR the histamines one, then healing and progress will be hampered. (Of course, flat out needing more bioavailable copper or to actually grab onto what is being consumed and use it is important...) The thing is, we can put as much food or RCP whole food/etc supp items into the body, if the body is perpetually waiting to run or fight, on some level, then the efforts nutritionally is going to be not fully seen... Digestive enzymes or Betaine to help food be broken down and used properly (& less histamines created from that angle) is helpful to consider too... Iron makes histamine on steroids. Low Magnesium increases mast cells and causes inflammation. What to do if you get a histamine response to food sources of retinol (cod liver oil, sometimes liver)? Sometimes we can get a food intolerance response from cod liver oil or liver (important components recommended on the Root Cause Protocol), but beyond stopping the item completely, what do we do when we know we ultimately need the nutrients? • Consider how much you are having each day - do you need to step quantities back? • Can you have it in another form? Freshly prepared liver cooked into a meal will be less histamines than dried liver capsules • Consider if there are any additives within the product you are using (sometimes natural ones can trigger a response - eg rosemary). Maybe a product change is needed? • Are you getting plenty of whole food vitamin c, supporting your digestion sufficiently and getting mag in your routine? These help reduce histamines in your body! • Consider what else is going on in your food intake, stress levels and environmental scenarios. One or more of these may increase your histamines and the cod liver oil or liver are just tipping you over the edge. KK: Kristan Kershaw: If we think of each of us having a bucket, and we normally would empty the bucket (via our natural antihistamine enzymes) quicker than we add to it... But when we can’t effectively make those enzymes, or fill the bucket quicker than we can make the enzymes, our bucket gets to overflowing, and histamine excess happens. How do we break down histamines? HNMT and DAO... What is needed to make them? Bioavailable copper & mag... So if the bioavailable copper and mag are caught up in inflammation elsewhere, our capacity to do many tasks in the body is reduced... It can appear like the best thing may be to cut high histamine foods or supplements back (& this can manage symptoms), but is this solving the problem? It’s managing symptoms yes... Options we suggest to assist with histamine reactions... > histablock May be helpful > allergy TX treatment or NAET (we have used Bowen Therapy too in our house, not as available in all countries). This option is fantastic because it reduces the systemic histamine and inflammation, so is helping at the base level, not treating a symptom. > increase bioavailable copper (you may need more whole food c & liver beyond what’s being consumed atm) > increase digestive support so less histamines are in the body from food > increase mag intake or try different combinations of mag. Another couple of things to add to that list which I forgot...(Alicia is working on these too, but others may need to note)... > donating blood regularly where possible is one way which can reduce inflammation (we mobilise the iron in the protocol, then it comes time where we need to move it on) > other steps to help reduce iron related inflammation - ACV, DE, rice bran/IP6 > EFT to reduce the body’s fear state/stress response Histamines are the FIRST ROAD BLOCK to the RCP!!! The RCP works for ~80-90% of people but of the remaining 10-20%, some of this will have severe histamine issues that prevent them from being able to implement the protocol. In these cases, Allergy TX may be a good place to start, to try to identify the aspects of their environment triggering the histamines and then take it from there. People with histamine issues will often present as SENSITIVE TO THEIR ENVIRONMENTS. Cipro (fluroquinolones) often have this effect on people as they suck Mg & Cu out of the body. Iron activates “histamine promotors” i.e. gastrin (in stomach) and H2O2 (in system). Fe doesn’t directly activate histamine but indirectly through the promotor. If having issues with the histamine and implementing the RCP, what part can you implement to deal with the iron? IP6? SRB? ACV? Lactoferrin? Try there. (Jim Stephenson) – study Brigham Uni (Utah) “Lab animals severely Mg-deficient had MUCH higher blood levels of histamine when exposed to substances that trigger allergies than animals getting sufficient Mg. It’s possible that Mg deficiency changes permeability of mast cell membranes, allowing Ca to more easily enter the cells. When that happens, histamine is released. In animals, Mg deficiency causes the release of substances that can act as immune cells such as mast cells & basophils and make them hyperactive – more likely to release histamine” – link to ASTHMA (see files) HISTAMINE INTOLERANCE: mould/black mould cause histamine release. It means they will have low Mg, low BioA Cu, and low B6. MAST CELL ACTIVATION DISORDER: = severe histamine issues. The mast cells are hanging out in the tissues so it’s a connective tissue disorder. The mast cells start to accumulate bc the body senses there is a sensitivity there. DAO (diamine oxidase) & HNMT (histamine n-methyl transferase) are critical for breaking down histamines released by the mast cells, and a super-sensitivity to one’s environment is due to mineral dysregulation. Those with this condition are usually deficient in Mg, BioA Cu, and are Fe toxic.
Histaminase (aka Ferroxidase)
Copper is unique in It’s need to be BIOAVAILABLE, which means that it is complexed INSIDE a key plasma protein called Ceruloplasmin! And when Copper is TOO LOW (Kristan & MANY MAG-pies!...) the protein can NOT load & when Copper is TOO HIGH (John Lee & MOST Practioners NOT TRAINED in Mineral METABOLISM...) the protein has been breeched from Oxidative Stress & Copper atoms LEAK OUT! 95% of our Copper in the blood is meant to be INSIDE Ceruloplasmin, & when that’s the case, it expresses as Ferroxidase enzyme, the MASTER Antioxidant enzyme in the body designed by MTHR NATURE to REGULATE Iron Metabolism (ALSO NOT taught in Practitioner training programs... Btw, another name for this KEY Ferroxidase enzyme is “Histaminase!” That means that it, too, is elegantly designed to STOP 🛑 the madness of Histamines, esp. the Migraines so associated with them, when you understand FULLY how the body works!
Hormone D
https://www.medicalnewstoday.com/articles/324022.php
Hydrogen Peroxide
people are being trained to think that they need more iron to make
hemoglobin. Trust me, I get that hemoglobin has four heme and that there's an
iron in the center of the heme, but that's usually not the problem. It's the
hydrogen peroxide that's in the system because of too much vitamin D, too
much ascorbic acid, too much sugar in the diet are the big three that causes a
massive rise of hydrogen peroxide. What I'm coming to realize is that hydrogen
peroxide is in fact what not only ages us, it's what kills us. It's the peroxidation
of the tissue, and that is a very significant form of oxidative stress.
Hydrogen Peroxide
Inflammation is copper leaking out of the protein because of too much hydrogen peroxide.
Hyperthyroidism
A deficiency of copper tends to be associated with hyperthyroidism
Hypothyroidism
LOW TMA MANGANESE: After years of 1MA testing, we routinely have found low manganese levels in the hair of patients with hypoglycemia (low blood sugar), hypothyroidism, adrenal insufficiency, kidney problems, and diabetes.(TraceElements117) Excess tissue copper = conditions Candida Albacans yeast infection, hypothyroidism, (unknown author) Why do hypothyroid people have low iron? There is actually 2 different kinds of anaemia. 1 is a true deficiency which is actually very rare considering we don’t lose iron other than through blood loss & a small amount through sweat, & the amount of iron lost in menses is actually quite minimal & not enough to make you anaemic. Then there is anaemia of chronic inflammation/disease which means that the iron in your body is not bioavailable so your body can’t use it. The latter kind is the most common and this is why taking iron supplements often don’t help other than to add to the iron that your body shuffles into storage in the tissues such as the liver (actually very dangerous in high amounts). The connection to hypothyroidism is that the liver runs on retinol (Vit A) and with all the iron being stored there it pushes retinol out. And guess what happens when you are low in retinol? The T4 receptor doesn’t work properly! If you have retinol deficiency it lowers your adrenal hormone production & increases cortisol. Retinol is also responsible for insulin release & a deficiency leads to excess glucose in the blood. Retinol is a metabolic requirement to make bioavailable copper which is EXACTLY what you need to make your iron bioavailable.
Hypoferremia
It is an established clinical FACT that “Hypoferremia” (Low serum Iron) occurs in ANY Inflammatory state. (Knudson and Wessling-Resnick, 2003) This is NOT a debatable point. It is NOT LOW for a “lack of Iron!” But what MOST practitioners have NOT been trained in is HOW the Iron REcycling System (RES) REALLY works and how dependent that RES is on Bioavailable Copper — NOT Iron!… Every 24 hours, our body is DESIGNED to produce 24 mgs of Iron that is used by our Bone Marrow — from our Long bones and Sacrum — to make the next batch of NEW Red Blood Cells for the body to use to carry that essential Oxygen. These RBCs are are designed to live for ~120 days, and then they need to be broken down and remade… And this is done EACH & EVERY DAY… And this needed Iron is supposed to get to the Bone Marrow by a network of Macrophages — PAC-men of the body — in our Liver and our Spleen who gobble UP those RBCs and break them down, and are then supposed to RELEASE that Iron so it can get BACK to the Bone Marrow. But there’s a CATCH… The Macrophages MUST have Ferroxidase enzyme function to release that Iron, and ALSO LOAD UP THE TRANSFERRIN (Iron Transport protein) for the ride back to the Bones… And that Ferroxidase enzyme REQUIRES Copper and Retinol to work properly. Most people are LACKING BOTH in their diet… When was the LAST time you had grassfed Beef Liver of Cod Liver Oil?!?…  In any event, LOW serum Iron is a CLEAR signal that your Iron REcycling is NOT up to snuff… It’s akin to MPG (Miles per Gallon) and should be at 100 in a women’s body (& 120 in a man’s)! And when it’s NOT, you have what’s clinically called “Anemia of Chronic Inflammation” (Weiss, et al, NEJM, 2005) which is a clinical sign of LOW Ferroxidase function, and therefor LOW Copper and LOW Retinol. The WORST thing you could do would be to put Mo’ Iron into your body that can’t handle what you’ve got now…There is a MAJOR difference between “Iron LEVELS” and Iron “Homeostasis.” The former is grade school math and the later is akin to Algebra… Understanding Iron status REQUIRES Calculus — NO NEED FOR RULERS…
Hypoglycemia
LOW TMA MANGANESE: After years of 1MA testing, we routinely have found low manganese levels in the hair of patients with hypoglycemia (low blood sugar), hypothyroidism, adrenal insufficiency, kidney problems, and diabetes.(TraceElements117)
Hypoxia
Hypoxia is a funny way of saying hydrogen peroxide, that's really what it is. Folks, PLEASE KNOW, that LACK of Bioavailable Copper CAUSES BOTH Hypoxia AND Cancer Metablolism!!! o Hypoxia is BOTH: -- Lack of Oxygen... as Oxygen is being CONVERTED to ROS... AND -- Inability to ACTIVATE Oxygen, which is Copper's GIFT to creatures that "breathe" it!... So the state of Hypoxia though, is going to lead to low ATP production, lack of bioavailable copper and/or magnesium. Increased hydrogen peroxide kills tyrosine, or the ferroxidase enzyme, it affects tyrosinase, and it affects catalase, and it also affects some very important glucose transporters and this is the energy regulator inside the cell. And when hydrogen peroxide is building in the cell because of inflammation, there's a wide swath of downstream effects, and that's what's leading to the decreased hemoglobin production, and then that's what leads to the myth-diagnosis, or hemoglobin reading, and the belief that the client is iron deficient because their hemoglobin is low (not knowing that that's a sign of copper deficiency), and for the fact that they're experiencing what's called low functional iron, which is known as anemia of chronic inflammation. It's increased hydrogen peroxide, what you are led to believe is a hypoxia lack of oxygen, but it's a it's a sleight of hand. It is a lack of oxygen, a lack of usable oxygen because this oxygen is tied up with two hydrogens and this is a very caustic element you know, it's bleach! It affects the cytochromes inside the mitochondria. It causes hair tissue to lose its color. That's what the loss of hair color is all about. It's a build up of bleach inside the system. It also causes the pH to drop. Hydrogen peroxide will cause a drop of pH by 1 to 2 points. It could go down as much as 5.5 when hydrogen peroxide is present. When copper is low, when retinal is low, when ferroxidase is low, there's going to be a rise in the inflammation and therefore a rise in hydrogen peroxide. Then, what's going to happen is the tissue is going to get stuck in an inflammatory state It means that there is no bioavailable copper. That's what we have to be careful of is that this idea of deficiency isn't necessarily a lack of something, it's the lack of bioavailability of a nutrient. It lacks its ability to activate and do the work that it's supposed to do.
Immune System -
Compromised immune system is too much unbound iron.
Immune System
dependent on bioavailable copper and reduction of toxic iron.
Inflammation
Inflammation is not a disease, but rather, damaged tissue that cannot function correctly.
Inflammation is caused by excess, unbound Iron, or Oxidative Stress. Inflammation is the result of Hydrogen Peroxide (H202) not being cleared by an antioxidant enzymes (such as Catalase and Glutathione Peroxidase) that are powered by Bioavailable Copper. Classic clinical indicators of Inflammation are LOW Magnesium LOW Bioavailable Copper
LOW Retinol>>each of which are routinely overlooked in standard blood tests. Inflammation & Inflammatory markers
Question: Ceruloplasmin exists in TWO states, ferroxidase enzyme and immunological protein (this form rises with inflammation). If my C-reactive protein (CRP = a marker for inflammation) value is low does it mean my ceruloplasmin ( 27 mg /dl ) exists as ferroxidase enzyme?
Answer: You need more markers to correctly assess inflammation.
CRP is one, but you need to look at other acute phase proteins or markers like : liver enzymes, neutrophil count, inflammatory cytokines and interleukins , some types of macrophages (M1), histamine level etc..
Homocysteine, hepcidin and ferritin are also deemed as inflammation markers.
Your hematology data may also give you good indications:
Although they are highly differentiated for hemostasis, platelets also have inflammatory and antimicrobial functions, linking clotting and immune events.
In the acute phase of inflammation, platelets and granulocytic cells such as basophils/mast cells, neutrophils and eosinophils are activated and in turn produce and release a number of soluble mediators that stimulate and regulate the inflammatory response.
Neutrophils, which are sometimes referred to as polymorphonu¬clear neutrophils (PMNs), are the primary cellular mediators of the acute inflammatory response. Their granules contain a variety of enzymes, peptides, and proteins and also undergo a respiratory burst. The intent of their armamentarium is to destroy and digest organisms and foreign material following phagocytosis, but gran¬ule contents may also be released and damage tissues at the inflam¬matory site. Measurement of some neutrophil products, notably myeloperoxidase, may be used to assess severity of inflammation
Eosinophils predominate in inflammatory sites associated with hypersensitivity responses and clearance of parasitic infections. Eosinophils are recruited to the site of inflammation by a number of factors including interleukin (IL)¬5, IL¬2, IL¬16, histamine, neutrophil peptides and some complement proteins
Lymphocytic infiltration is often a prominent feature in chronic inflammation. Lymphocytes may act as specific effectors of cyto¬toxicity, or they may secrete antibodies or cytokines that participate in tissue damage or inflammatory cell recruitment. Lymphocytes can also participate in nonspecfic inflammatory reactions, recruited as a consequence of elevated cytokine and adhesion molecule levels.
Macrophages tend to accumulate at the site of injury following lymphocytic infiltration and may also be the primary response to chronic diseases such as mycobacterial infections. They serve as antigen presenting cells (APCs) and help drive and perpetuate the immune response, releasing a variety of inflammatory cytok¬ines and cytokines that stimulate lymphocytes. However, they play a predominant role in the regulation and resolution of the inflammatory response.
While not considered mediators or primary participants in inflammation, red blood cells can be affected by and reflective of inflammatory processes. Red blood cells are very susceptible to immune¬ mediated and other processes that accelerate red blood cell destruction. The immune¬mediated process and potentially the red blood cell destruction itself may trigger an inflammatory response. The most common red blood cell finding with inflammation is a non-regenerative, mild to moderate decrease in red blood cells termed “anemia of chronic disease (ACD)” or sometimes “anemia of inflammatory disease.” (Cf numerous Morley Robbins 's posts about it)
Serum chemistry information such as increased globulins due to increased immunoglobulin and/or APPs), or coagulation informa¬tion such as fibrinogen may provide additional evidence of the presence of inflammation.
Many cytokines and chemokines contribute to inflammation; some facilitate leukocyte chemotaxis to the site of injury, while others modulate immune cell function. The cytokines that are best known for stimulating and perpetuat¬ing inflammatory responses are IL¬6, IL¬1, IL¬2, TNF¬a, IFN¬g, and transforming growth factor (TGF)¬b.
So to sum up it needs a lot of tests to accurately assess one's level of inflammation and someone qualified to know all these markers and their dynamic. As Morley said there is no known way to distinguish the normal ferroxidase and the acute phase protein ceruloplasmin.
If in doubt, I think it's better to seek a professional consult with Morley or RCP consultant.
Morley Robbins STELLAR RESPONSE!, Yann Guého...
Klara Lommel, as noted above, were it as simple as CRP... I find THAT ^^^ marker to be essentially WORTHLESS as an indicator of the RAGING INFLAMMATION that MOST have in their tissue cells.
This would ALL be solved if Labs provided, or Doctors DEMANDED BETTER & MORE RESPONSIBLE LAB TESTS, so we would KNOW the Ferroxidase fraction from the Immuno-reactive fraction... (please know, they tell the Rats in the Research studies ALL THE TIME!...)
A votre sante!
Morley Robbins (to Amel Kates): Please understand that Iron ACTIVATES NLRP3, the “Danger Sensor” of the cell, aka the Inflammasome. (Nagamura et al, 2015) Loose translation: Iron CAUSES Inflammation!
Iron is ALSO the catalyst for Oxidative Stress, otherwise known as RUST! It is well know in scientific circles the way we know Apples fall due to gravity...
Here’s an interesting study linking these dynamics:
https://www.hindawi.com/journals/mi/2014/147040/
Regrettably, C-reactive protein is NOT an effective marker for Inflammation. Under ceratain conditions, esp. related to endothelial tissue, it is effective. But I have MANY clients w/ RAGING Chronic Inflammation, but “normal” CRP. I have learned to respect it when it’s elevated, ignore it when it’s normal, & proceed to find PROOF that Inflammation is, in fact, a significant metabokic dunamic...
Hope that helps!
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Oxidative Stress Markers and C-Reactive Protein Are Related to Severity of Heart Failure in Patients with Dilated Cardiomyopathy
Innate Immune System
Runs on copper Infection = copper status is weak
Insomnia
Insomnia is caused by excess unbound iron and low bioavailable copper. When we have an increase of histamines, the DAO and HMNT degrades histamine but they are copper dependent. Melatonin/insomnia - Melatonin is an antioxidant that reduces oxidative stress - Melatonin neutralises OH* - Melatonin reduces histamine response - Histamine degraders rely on bioavailable copper to work (DAO and HMNT) - Excess glutamates in the body reduces melatonin - Unbound iron causes OH* and oxidative stress - Reduced melatonin = insomnia - Melatonin supplements can make the body lazy in making it so not an ideal solution What can you do? Get on to the RCP by increase bioavailable copper so it can: - create more histamine degraders so it can neutralise the response and less melatonin gets used - Help to move the iron away from the tissues and organs that is causing the inflammation (histamine response) Retinol is needed to load copper onto the ferroxidase enzyme so it can do what it does best - help all the oxidases in the body work properly. Magnesium helps to guard against oxidative stress but you still need to work on the iron that is causing the unrest. Insomnia - - reduce stress - Look towards the sunlight before 10am each day to reset body clock - Increase bioavailable copper by doing the protocol = grassed fed beef liver, whole food C and bee pollen. Also to increase animal base retinol by having grassed fed butter, egg yolks, beef liver and CLO. - Temporary reduce the glutamates in the diet - some foods such as Parmesan, mushrooms etc are high sources. Avoid MSG and other sources of MSG like hydrolysed soy protein, soy sauce etc..
Type a question
Iron
80% of the Iron in our body is used to carry oxygen to our cells (70% in Hemoglobin and 10% in Myoglobin). As such, Iron is a vital nutrient. But it REQUIRES Bioavailable Copper to regulate its usability, otherwise Iron runs around like a 4-year old with a hammer -- wreaking havoc inside our cells, causing Oxidative Stress and Inflammation, which affects MANY metabolic pathways. Males have about 4,000mg of Iron in their body; females about 3,500mg; children about 3,000mg or less. A KEY dimension to Iron is the fact that it is “recycled” each and every day. (See The Reticuloendothelial System.)
Kidney Disease / Kidney Issues
> Need to be cautious with implementing the protocol. >Can have issues with magnesium and potassium not clearing efficiently through the kidney. > Ionic Mg is preferred
Iron -Non-Heme
is toxic
Iron Dysregulation
copper is supposed to be complexed inside the ceruloplasm protein. That's where it belongs in a normal, healthy, functioning human being. What has happened is our environment, in large part because of our food system and our farming system, has created toxic levels of hydrogen peroxide in our body. We're not able to make catalase enzyme adequately, and so the hydrogen peroxide is tweaking the ceruloplasm, which is allowing the copper to leak out and become dysregulated. These are very definitive signs of what I call iron dysregulation.
Iron Fear Connection
o Fe-ar ATTRACTS Iron via a drop in our pH when in a state of “Fe-ar!” o Iron ACTIVATES Fe-ar via Iron’s KNOWN Role to activate the Inflammasone, aka NLRP3 Protein in the Nucleus... (Nakamura et al, 2016, "Activation of the NLRP3 inflammasome by cellular labile iron): [NOTE: "Labile" does NOT mean "Free" -- it means "REACTIVE!"] https://www.ncbi.nlm.nih.gov/pubmed/26577567 The interface & interaction of Fe-ar Fe (Iron) is MIND-NUMBING & COMPLETELY OVERLOOKED... And best of all, Ally Allÿ has shared an explosive 🧨 article on HOW Fe-ar CAUSES BOTH Hypoxia AND Cancer!!! (Excess Unbound Iron, coupled with a LACK of Bioavailable Copper is a DEADLY COMBO!...) https://www.researchgate.net/publication/329407268_How_Chronic_Fear_Results_In_Hypoxia_in_Tissues_and_Cancer_in_Humans_through_Bohr_Effect?fbclid=IwAR1T2O8i5MbqHQ30MzWzwiQNMppEdZ7Cwh4X6vS5pRc8qEiSYmE1h4m1sO4 (Sorry for the SMALL font... )
Iron - Labile
Non-– transferrin – bound – iron, It's sort of in the cell but were not sure where it is people should be freaking out about that…so 1. if it's not in transferrin 2. and it's not in ferritin it's called labile iron. Labile Iron is the iron that creates chaos in the cell. People should be freaking out about the.
Iron Overload - Toxic sources
TB: 1. Fortified iron in foods in a big problem. I know I grew up eating cereal (Australia)(remember the slogan iron man food!). More so in USA as it is in wheat, rice.. 2. Low minerals in our food especially magnesium, with the promotion of calcium rich food and calcium supplements AND the latest craze - vitamin D. Vitamin (hormone) D supplements is devastating on both magnesium and potassium status. Magnesium protects us against oxidative stress. 3. Lack of bioavailable copper which is part of the iron/copper cape known as ceruloplasmin. The enzyme ferroxidase takes iron and copper around the body fulfilling functions. Lack of ferroxidase function means both iron and copper are unbound. What alternative practitioners do? Chelate copper because the unbound copper is high. Treating it with zinc is a bad idea. 4. Stress increases iron. We are living in a very hard and fast paced society which we are virtually running away from tigers on a daily basis (fight/flight). This causes magnesium loss in which leads to number 2. 5. Generational loading of iron - your Mother's load of iron and passing them onto to you and you eating iron rich foods etc? Early commencements of menses is a sign of iron/copper dysregulation. 6. Anemia of chronic inflammation - wrongly diagnosed as iron anemia. It is a lack of functional iron not deficiency. Treating it with iron supplements may provide temporary relief but then you are forcing the body to accept the iron until the body can work the excess iron out if the bloodstream again. Ask yourself the question- where is the iron going especially infusions? We have no mechanical means of excreting iron other than blood loss. 7. We have shied away from eating what our ancestors have eaten - CLO and liver. These are excellent sources of iron, copper and vitamin A(retinol). Retinol A gets depleted by hormone D supplements which then causes lost of Ceruloplasmin function ferroxidase, which causes unbound iron/copper, which causes the body to store the unbound iron away from blood. It stores primarily in our liver, then other organs, muscles, skin, intestines, brain, heart etc.. Iron overload is hidden but can present itself with symptoms such as Alzheimer's/Parkinson/ neurological disorders, diabetes(iron overload on pancreas) etc..
Iron - when mobilized
When the iron starts to come out of storage, it's going to be a clear sign that there's iron mobilization. That is going to be met with some symptoms. That's why there's
importance in doing the donations wherever
possible. Short of doing donations, you're left with IP6, lactoferrin. [inaudible
01:42:28] would tell you that fasting is a very effective way to get rid of iron. At least he's found it to be that way. There maybe other dietary agents we can use. A client of mine just brought to my attention that there's a Chinese herb called Huang Quin. It's known as Baicalein. It's a really effective iron chelator. It's been used just for a few centuries in China. I think these iron issues goes back in time
and I think the amazing thing about acupuncture is they've been working with
herbs for millennia. I think they've been moving minerals all this time because we
don't know how to translate Chinese, it's not easily understood. There are notable herbs, spices, essential oils, what have you that can help to bind up and chelate that iron.
Iron, Unbioavailable (low functional iron)
You may have low functional iron though. Insufficient retinol and bioavailable copper means that your body can't adequately use the iron, even if it present. Iron doesn't move itself around the body. It needs a protein called ceruloplasmin with enzyme function to allow the iron to move from storage in the tissue into the blood
Iron Clearing Options
Other options to lower iron turmeric paste, CoQ10, quercetin, apo-lactoferrin, etc.? Are they eliminating iron fortified foods in the diet, i.e. cereals, breads, tortillas, hamburger/hot dog buns, bagels, pizza, rice, cornmeal, etc. etc..?
Iron Infusions
Decimate Retinol A in the body An iron transfusion will put more iron in the joints and organs, liver, heart, brain, eyes, etc. We have to make the iron that is already in our bodies FUNCTIONAL (mobilized) and we do that by increasing the bio available copper complexed within ceruloplasmin to make the ferroxidase enzyme (ceruloplasmin ferroxidase enzyme) which regulates the iron and gets it moving through the blood. We also need the retinol A to load the copper into the ceruloplasmin. Having an iron infusion will make health worse causing joint pain,etc.
IVIG - the need for IVIG is a sign of low copper
the IgG response is triggered by iron and the innate and acquired immune system keys off of copper. So if there's something wrong with your immune system, it's an imbalance between copper and iron.
Ketogenic Diet
"The healing diet which is primarily gluten and dairy free ketogenic diet with moderate intake of protein and plenty of animal fats does not work as it should be as long as there is excess iron in the body." [The Iron Elephant] The Ketogenic diet is very stressful on the body and depletes the minerals at a much higher rate. The daily magnesium, potassium, and sodium requirements are increased significantl.
Kidney Stones
Morley Robbins: What folks also MUST KNOW: ALL STONES are CAUSED by CopperIron Dysregulation, esp. INSIDE THE RBCs: https://www.ncbi.nlm.nih.gov/m/pubmed/24360074/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220551/ https://www.ncbi.nlm.nih.gov/m/pubmed/20210657/ While these articles are SILENT ON THE MINERALS, I can ASSURE you that o Excess, unbound Iron CREATES the Oxidative Stress in the RBCs AND Kidney, AND o LACK of Bioavailable Copper GUARANTEES LOW FUNCTION OF KEY ANTI-OXIDANT ENZYMES -- Glutathione Peroxidase -- Catalase -- CuZn-SOD (Copper is CATALYTIC & Zn is STRUCTURAL!) Also, MORE SILENCE on the ESSENTIAL role of Ferroxidase enzyme, the MASTER Anti-Oxidant Enzyme... It's time we ALL step up our game & START FOCUSING ON THE METABOLIC ORIGIN of ALL this chaos... PLEASE! A votre sante! Jen Fokkens: I've heard Morley say that the oxalate issues is caused by iron overload and recommends eating cabbage as part of your diet and the protocol to remove iron from the gut and heal leaky gut that allow for absorption of oxalates. If they are from calcium build up the protocol will redirect the calcium back to the bones.
Law of Attraction
The Law of Attraction doesn’t care if you perceive something to be good or bad, or whether you don’t want it or whether you do want it. It’s responding to your thoughts. Clean up your thoughts! Project positive and affirming thoughts, not negative and hindering thoughts!
Learning Disability
ELEVATED LEVELS OF MANGANESE Elevated levels have been found in patients with multiple sclerosis, learning disabilities and Parkinson's disease.(TraceElements117)
Leukemia
I believe there is a strong connection Btwn Leukemia & LOW Bioavailable Copper & LOW REAL Vitamin-A... “A” votre sante! I found this Letter by Leslie M. Klevay, MD when I asked Dr. Google: "Leukemia Copper deficiency" https://www.tandfonline.com/.../10.1080/10428190802035958... Folks, Please KNOW that Leslie M. Klevay, MD, ScD can say MORE in FOUR Paragraphs than MOST Researchers in FORTY pages... He is my "Go To!" Copper Guru, and when I want to get the skinny on the breadth & depth of Copper, I simply ask Dr. Google: "Copper condition that I'm interested in" + Klevay.... I'm batting 1.000 using that ^^^^ Combo for Copper issues... "A" votre sante! P.S. Please NOTE the reference #6: Elvehjem & Sherman (1932) that defined the ESSENTIAL role for Copper in Iron metabolism... And that 1932 study references a KEY study from 1928 with Hart, Steenbock, Waddell & Elvehjem that "showed definitely" that Copper was KEY to the use of Iron salts for Hemoglobin synthesis... And finally, that 1928 study came on the HEELS of Warburg & Krebs (1927) who bled birds to the point of near-death, and those two German Gurus NOTED the 3 to 6X RISE of Copper Enzymes (Ceruloplasmin and SOD) in the Birds' blood in response to the EXTREME LOSS OF IRON... And what do we "Cupernicans" conclude from those THREE (1927, 1928, 1931) EARLY & DEFINITIVE studies involving Copper & Iron?!?.. Copper RULES... Iron DROOLS...
LDL Cholesterol
Spike in LDL or High LDL? t’s a deficiency in whole foods Vitamin C, necessary for copper utilization, which allows the LCAT enzyme to convert LDL to HDL! LCAT = Lecithin Cholesterol Acetyl Transferase CONVERTS LDL (so-called "bad" Cholesterol) into HDL (so-called "good" Cholesterol)...
Low Energy
If you are someone who needs more carbs, or have the need to eat very regularly to keep your energy up, listen up! You are likely dealing with very low bioavailable copper, mag/adrenal stress and bodies under overall metabolic stress from excess unbound iron. When the mitochondria cannot access bioavailable copper and mag, it cannot complete all five steps of the ATP creation process (from Complex I through to Complex V)... and the body will have to use other ways to access energy. This interrelates with the capacity to deal with stress from exercise as well as day to day energy conversion. A good continuing example beyond day to day use of energy by simpler carbs, not fat... is when we suddenly exert (this could even be a big walk or other seemingly minimal exercise, if we aren’t used to it) and then are tanked for energy levels for an extended time. This is when our body has used up glycogen and is replenishing those stores. It’s also putting stress on our adrenals and other systems as they desperately try to mobilise energy, but don’t have the bioavailable copper and mag (etc) to do so. When we are pulling on these glycogen stores all the time, we will reach ‘exhaustion’ and not be able to create energy as others may (who have better mineral recycling in place). The exhaustion also comes from not being able to get the products of exhaust (often by products of inflammation in this context) out of the body. As the minerals start to flow and recycle better, reducing oxidative stress, this often will transition to where the body doesn’t want carbs so much and needs fats (which is actually a far better source of energy for the body). Ultimately, addressing the underlying excess unbound iron and getting bioavailable copper up (which will increase bioavailable iron).... doing the Root Cause Protocol.... will give the body the best chance of improving recycling and improving our capacity to make energy.
Lyme
LOW Iron in the Blood typically means HIGH Iron in the Tissues... Your symptoms (Lyme, COMT++, High Estrogen, etc) are ALL signs of Excess, Unbound Iron. Your bloodwork is NOT being interpreted completely. Hormone Dysregulation and Unchecked Pathogens (they ALL live on Iron!) are simply FURTHER signs of CopperIron Dysregulation...
Liver Enzymes
liver enzymes - Morley Robbins learned today purpose of the liver is to use metals to run enzymes, liver enzymes too high=too high metals
Low Fat Diet -
LOW retinol-A intake, low bioavailable copper intake, move away from ancestral eating, low fat foods often laden with sprays and processed than previous generations.
Lyme
People obsess about how to treat Lyme disease not knowing that iron causes it. Don't loose sight of the big picture.
Macrophages
macrophages make ceruloplasmin pivot point between iron metabolism and metabolic breakdown INFLAMMATION instead of recycling iron you are storing iron 900 billion macrophages int he body
Magnesium
So what we are saying here is that Mg is most likely the main reason why potassium/calcium channels/pathways are blocked or sluggish. Since all ATP is actually Mg-ATP we start to get more proof that low magnesium can impede other areas of biology that Mg was never thought to have an active role in.
Mg-ATP
Mg-ATP is involved to make them all work. It means to re-activate the "blocked" channels one should have more Mg and less Fe. Then more Potassium will flood into the cells, right?
Mast Cell
mast cells store iron Lower MAG level increased sensitivity to environment Lower Bioavailable copper = increased sensitivity to environment low MAG in combo with w/ low bioavailable copper = more mast cells produced enzymes breakdown histamines (DAO and HNMT) NEED MAG, Bioavailable Copper, and B6 to make those enzymes work. IF enzymes don't work, the histamines will wear you out - becoming a stressor, then becoming a histamines intolerance, leading to perpetual loss of MAG and potassium inside the cell as a perpetual state of being flooded with calcium and sodium, where it's supposed to be outside the cells, it's going inside the cell. histamines are used to respond to environment mast cell house histamines Abundance of mast cells which have an abundance of histamines Increase of mast cells in MAG and Copper deficient organisms. Mast cells MAG deficiency, mast cells COPPER deficiency. Mast cell issues coming from tissues that have been subjected to notable stress. Iron makes histamine on steroids. Low Magnesium increases mast cells and causes inflammation. MAST CELL ACTIVATION DISORDER: = severe histamine issues. The mast cells are hanging out in the tissues so it’s a connective tissue disorder. The mast cells start to accumulate bc the body senses there is a sensitivity there. DAO (diamine oxidase) & HNMT (histamine n-methyl transferase) are critical for breaking down histamines released by the mast cells, and a super-sensitivity to one’s environment is due to mineral dysregulation. Those with this condition are usually deficient in Mg, BioA Cu, and are Fe toxic.
Magnesium Burn Rate (MBR) -
Under any form of stress to the body (physical, emotional, nutritional, electrical, etc.), Magnesium is lost as a metabolic response. Because when the body is under stress, it makes energy (aka. “Mg-ATP”) as a response. Under extreme and/or sustained stress -- and failure to properly re-mineralize -- the body loses its natural ability to respond to stress, and Oxidative Stress (aka. “rust”) builds up throughout the body. Magnesium deficiency (low Magnesium RBC) is the recognized precursor to inflammation. When the body is expressing optimal Ferroxidase activity, the MBR will be at a minimum.
Magnesium Taurate
Morley's never had a client react to it. Usually well received form of mag. If there is a buildup of iron in the hears (not uncommon) might make someone sensitive. BEST one: Cardiovascular Research
Menopause
Slow/sputter around age 55-56, anything earlier is not ideal.
Menses
o Average iron loss for menses: 6-10 mg... o Let's double that for heavy menses: 12-20 mg... o 1 pint of blood for a typical donation: 250 mgs...
Mercury
The mercury myth, we've had mercury on this planet since day one. Mercury has been used in amalgams since the civil war in the 1860s, but it didn't become a problem until 1983. Hmm, interesting. What happened in 1983? That's when they introduced high-fructose corn syrup that causes liver copper to collapse and liver iron to rise. Why is that important? Because there's an enzyme in the liver that clears mercury that's based on copper. The problem is the relationship between copper and mercury is well known. It goes way back to antiquity and the body when it's properly balanced can clear mercury very easily. -Just know that if these heavy metals do express, you clearly have someone who's compromised. The ones that people worry about the most obviously are mercury and aluminum, for good reason, but keep in mind that people who have mercury issues have a bioavailable copper issue, and people who have aluminum issues are usually dealing with magnesium issues. To correct an aluminum issue, you get relief using silica or magnesium. I've seen both be very effective, and to deal with the mercury issue, you've got to correct the copper iron dysregulation. -I do not ascribe to Chris Shade or formerly Andy Cutler's protocol. I think those are absolutely insane approaches to solve this problem, when the mercury is rising, you know you have a liver that's out of balance through a mineral standpoint. -You may find is people's mercury may rise as their adrenal function comes online that the body is going to be expressing it out.” People with alleged Hg issues, imho, are REALLY dealing with CopperIron Dysregulation, which disrupts the natural detox pathways inherent in our immune system. Mercury will not go out of a body that is low in bioavailable copper. The so-called "low dose" chelation is STILL a Bulldozer, and the last time I checked, those mammoth machines are NOT able to distinguish boulders from rose bushes... >Increase bioavailable copper and let copper deal with the mercury. > Mercury isn’t the focus here because iron is far more damaging than mercury. If you give the body the right tools, you can get mercury under control. I have had clients who had high mercury on several HTMA, did the RCP, and it is normal.
Milk Thistle
stimulates detox, attacks the guest, conflicts with the over-riding philosophy of the Root Cause Protocol: “strengthen the host” Milk Thistle is a polyphenol which means it requires polyphenol oxidase which is a copper dependent enzyme.
Migraine
Broadly speaking, Migraines are the result of “Histamine Intolerance” which results from a LACK of Bioavailable Copper, Mg & B6 to activate two KEY Enzymes, DAO & HNMT, designed to break down Histamines... Copper is unique in It’s need to be BIOAVAILABLE, which means that it is complexed INSIDE a key plasma protein called Ceruloplasmin! And when Copper is TOO LOW the protein can NOT load & when Copper is TOO HIGH the protein has been breeched from Oxidative Stress & Copper atoms LEAK OUT! 95% of our Copper in the blood is meant to be INSIDE Ceruloplasmin, & when that’s the case, it expresses as Ferroxidase enzyme, the MASTER Antioxidant enzyme in the body designed by MTHR NATURE to REGULATE Iron Metabolism (ALSO NOT taught in Practitioner training programs... Btw, another name for this KEY Ferroxidase enzyme is “Histaminase!” That means that it, too, is elegantly designed to STOP 🛑 the madness of Histamines, esp. the Migraines so associated with them, when you understand FULLY how the body works!
Mold / Black Mold
HISTAMINE INTOLERANCE: mould/black mould cause histamine release. It means they will have low Mg, low BioA Cu, and low B6.
Mouth Breathing
Mouth breathing Minerals don't specifically relate to mouth breathing in isolation, but, they absolutely contribute to the list of possible reasons... here's just a few reasons why. 1) Inflammation from the underlying mineral imbalances, making it physically harder to breathe through the nose 2) The body needing more air intake as it doesn't exchange oxygen/carbon dioxide well due to many factors including excess carried weight, insufficient bioavailable copper in the body to move the oxygen around (hint: it's not just hemaglobin involved in that).. etc 3) Food intolerances leading to excess phlegm/congestion and forcing the mouth to be used when asleep (this partially ties in with #1) 4) Tongue and lip ties causing muscular changes from early in life, which prevent the palate from expanding as it naturally would, which also hinders breathing. (These continue as a person gets older and becomes more and more of an impact on their health, yet they never realise the tie involvement) 5) Physical accident/structural changes (the stress from these will likely contribute to above mentioned mineral dysregulation too) I'm pretty sure I could think of more, but, this gives you an idea of how it can link in with the minerals on some level anyway
Moringa Leaves
Moringa leaves and dry cap supplements However, then her reading went to 9.9 in two weeks (can’t think of anything more miraculous!!!!!) by simply adding a cup of fresh leaf Moringa tea and dry leaf power tablets (1 gram) to her daily routine that included cod liver oil (but only more recently, for a ~3 months). Moringa leaves compared to common foods Values per 100gm. edible portion Nutrient MoringaLeaves Other Foods Vitamin A. 6780 mcg Carrots: 1890 mcg Vitamin C. 220 mg Oranges: 30 mg Calcium. 440 mg Cow’s milk: 120 mg Potassium 259 mg Bananas: 88 mg Protein 6.7 gm Cow’s milk: 3.2 gm from Nutritive Value of Indian Foods, by C. Gopalan, et al. (1980, 1989) You can also see a more recent paper that Morley sent me below (as it compares an expanded list of nutrient‘s values of different parts of the same plant) Food Science and Human Wellness 5 (2016) 49–56 Moringa oleifera: A review on nutritive importance and its medicinal application -https://www.sciencedirect.com/science/article/pii/S2213453016300362
MTHFR
Remember that many of us have MTHFR and not know about it. I don’t think it is something to be really concerned about. From Morley: Before this thread gets too much more attention, I think it's KEY to provide some MUCH NEEDED context for your observations re "Methylation"... I am often reminded of the pivotal scene in "Ice Age-2" when one of the animals yells "SQUIRREL!" and the critters go absolutely BONKERS!... It happens ALL the time on FB... 😉 What I've noted over the last 4 dog years on FB are that the following topics -- ABSOLUTELY -- set the MAG-pies & MAG-nets into a frenzied state of distraction: o Lyme Disease... o Thyroid Disorders... o Vitamin-"D"eficiency..., and yes, o Booga-wooga "Methylation..." among many others, I might add... And Larry, I absolutely understand and respect your position on this, but I feel compelled to set the record straighter... I was told by a colleague in France recently that Hippocrates would enjoy my writings. When I asked "Why?" she responded that he was DEVOTED to finding the CAUSE of the CAUSE of the CAUSE... And as soon as she said that, I fully understood how the MAG group ADDS VALUE and distinguishes itself from MANY of the groups that yammer away on FB. Let me explain... "Cause" = Symptom = "High Homocysteine" "Cause of the Cause" = Metabolic Dysfunction = Hypomethylation "Cause of the Cause of the Cause" = Mineral Dysregulation = TOO LITTLE bioavailable Copper and/or TOO MUCH unbound Iron And it's important in the process that we ALL NOT fall prey to someone yelling "Squirrel" (however well intentioned they may be...) without explaining what's REALLY going on. In light of that, I would sincerely ask that you read the following study VERY CLOSELY: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798916/ I think the LAST sentence of the Abstract is worth the price of Admission: "Hypomethylation and tHcy elevation can be attenuated when Choline or Betaine is available." That, my friend, is a BLOCKBUSTER finding... And what are the RICHEST sources of Choline? http://www.gbhealthwatch.com/Nutrient-Choline-TopFoods.php What I've learned in 8 yrs of health coaching is that the VAST majority of folks STOPPED eating Liver loooooong ago. (I've chatted with 3,000+ folks and 8 MAG-pies actually got excited that they could eat Liver again...) And for those that want to dig a bit deeper into this issue, please take the time to read what one of the experts on Choline metabolism, Chris Masterjohn, PhD, has to say about all these dynamics in his entertaining article: "The Sweet Truth of Liver & Eggs": https://chrismasterjohnphd.com/2010/11/23/sweet-truth-about-liver-and-egg-yolks/ And please NOTE the number of Methyl Groups (CH3) that are naturally found in Choline as noted in the figure below... So what's my point?... It's VERY vogue and hip to talk about Methylation... 😉 But truth be known, MOST practitioners and websites know VERY little about the TRUTH of this metabolic condition and how impacted it is from Choline deficiency, Copper deficiency and Iron-induced Oxidative Stress: o High Homocysteine (tHcy) is a clinical sign of LOW bioavailable Copper... o There are 200+ Methyltransferase enzymes that we rely on. Now, I've only studied 10 of them (e.g. COMT, PEMT, HNMT, etc.) very carefully, and THOSE ^^^^ are ALL dependent on bioavailable Copper. I don't think MTHR NATURE plays dice, so I take a leap of inference that ALL MT enzymes rely on Bioavailable Copper, aka, Ceruloplasmin... o When Homocysteine rises folks are QUICK to jump to B6 and B12 issues, not knowing that Folate, B9, has an ABSOLUTE need for bioavailable Copper (private conversation w/ Leslie M. Klevay, MD, PhD). Again, LACK of Copper is the KEY issue... o And what disrupts Copper metabolism in a NY minute?... None other than excess, Unbound Iron -- something that would be quite COMMON in an older male that had NO CLUE that Iron was building DAILY in their Liver, in large part due to our M.oronic D.iet that includes OBSCENE levels of High Fructose Corn Syrup (HFCS). o And as the research ALSO points out, High Hcy is due to a LACK of Choline in the diet. I would much prefer that MAG-pies get this VITAL nutrient from a food source, rather than some synthetic concoction coming from a Test tube -- Sorry, I'm weird that way... And I'm hoping that others feel the same, as well. Said another way, I do NOT think you were born with a "TMG Deficiency!" nor do I think you developed a "TMG Deficiency..." I do, however, have confidence that: o your diet was likely sub-par for some portion of your life -- most are... o you likely had too few foods that were rich in Choline or Betaine... o you likely had your fair share of "Stress!" that affected your Mg... o you likely had too little bioavailable Copper... both in your diet, and was affected by the Mg deficiency ^^^^ that is SOOOO prevalent in Society... o you likely had too much unbound Iron from ABOVE ^^^, and yes, o you had Liver "congestion" that was the result of the above... Sooooo, I'd like you and the folks that synced with your message to realize that your o High Homocysteine was CAUSED by o Hypomethylation that was CAUSED (Cause of the Cause...) by - too few Methyl Groups (i.e. Choline) in your diet... - the wrong bioavailability of your B9 (due to a lack of Copper...) - too little bioavailable Copper, aka Ceruloplasmin... o Which was CAUSED (Cause of the Cause of the Cause...) by Excess, Unbound Iron that is akin to a WRENCH IN A GEAR... Again, MAG is ALL about focusing on the TRUE origin of an issue, NOT putting a spotlight on twisted, allopathically-myopic & minerally-deficient thinking that keeps us focused on ANYTHING & EVERYTHING but the bedrock of our maladies: Mineral Dysregulation that is CAUSED by Iron Overload that affects the elegance of Mg status and bioavailability of Copper... It IS, imho, the AXLE around which ALL of our Symptoms (aka "Cause") turn. And my last licks are to share what I learned last night talking with Kitty Martone, who runs a very popular & informative FB group on Estrogen Dominance, as we were creating a Podcast for our communities... In her formative years as a nutritionist, she spent many years working with Robert Marshall, MD, who specializes in Gut Health and pH balance. What they learned in his Center, through regular 23andme testing, is that the "Methylation issues" that surfaced on initial MTHFR testing CHANGED & IMPROVED as the metabolic health of the client improved. Now that is an ABSOLUTE Bombshell, and CONFIRMS what I have LOOOOOOONG suspected: Genes flip "On" & "Off" ALL THE TIME -- depending on the metabolic load & stressors of the individual... And NO ONE ever thinks to "test their 'broken' genes" -- again. So, as the mineral dysregulation that's at the HEAD of all this CHAOS subsides, the Stress on the Genes CHANGES and metabolic function improves... And I believe that you more than PROVED that to yourself. So, please forgive my obsessively LONG comments, but I simply want to make sure that we're ALL keeping our eye on the AXLE and NOT the seats of that ever-present Ferrous Wheel that RULES our health & well-being... More than anything, I want Hippocrates to admire our commitment & devotion to TRULY UNDERSTAND the Cause of the Cause of the Cause... A votre sante! https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798916/ Teresa has shared some great resources above. The protocol uses food sources of b, so there is no concern for those with MTHFR. The liver component especially is a powerhouse of nutrients beyond just B’s.... I have a whole thread of saved resources around this topic - some now refer to the old website, but there are still a lot of gems in it. Https://www.facebook.com/groups/388392151228860?view=permalink&id=1318313224903410 - Admin/Root Cause Protocol Consultant Development Manager
Multi-Vitamins
Morley Robbins There are MANY reasons to NOT take a "Multi-vitamin" but I'm assuming that this DC is NOT talking about Standard Process Catalyn, which is a beast of a different sort... But here's the skinny on WHY NOT Multi's: o TOO MUCH Calcium that BLOCKS Mg Absorption... o TOO MUCH Zinc that BLOCKS Copper absorption... o TOO MUCH Iron -- it's ABSURD how much MOST Multi's have... o TOO MUCH Mn, Mo, and other Micro-minerals that overwhelms the body o The Vitamin-A is SYNTHETIC and does NOT work, and if it's based on Beta-Carotenes, then DIVIDE by 12... as it takes 12 Beta Carotene to = 1 Retinol... o B-Vitamins that are SYNTHETIC and therefore made from Coal Tar Derivatives... Look it up -- you'll NEVER use synthetic B's again... o Hormone-D -- need I even say anything about this?!?... o Ascorbic Acid KILLS Ferroxidase enzyme function and STORES Iron -- neither of which makes sense... o And ALL Multi's started out as a "Slurry," which implies WATER, which implies FLUORIDATED Water as 75% of ALL Water systems are now fluoridated... So, instead of being an "insurance policy," imho, Multivitamins are nothing more than a "death sentence." I would assert that your DC should KNOW BETTER... https://pdfs.semanticscholar.org/1ae0/608396d55120efcb6923c3d1dfa970f64bbb.pdf?fbclid=IwAR17J2ySwqcet0ho6jQOFMvBWgX7uz5zSlHqmaOk1-sShQT-eL6aWEzE46k The Truth About Vitamins in Supplements By: Robert J Thiel, Ph.D., N.M.D. Abstract: Even though natural health professionals agree that humans should not try to consume petroleum derivatives or hydrogenated sugars, most seem to overlook this fact when vitamin supplementation is involved. This paper explains some of the biochemical reasons that food vitamins are superior for humans. It also explains what substances are commonly used to make vitamins in supplements. Furthermore, it explains some of the advantages of food vitamins over the non-food vitamins that are commonly available. Thiel, R. “The Truth About Vitamins in Supplements”. ANMA Monitor, 2003, 6(2)
Multiple Sclerosis
We have found that patients who suffer from neurological disorders such as multiple sclerosis and Parkinson's disease, usually have a severe copper deficiency on their TMA tests. These observations have been reported by others. Douglas reported finding significant differences in hair copper levels in 40 multiple sclerosis patients compared to 42 control subjects. Similar findings have been observed in patients with Parkinson's disease. Animal studies have also confirmed a copper relationship to this condition. Levels of dopamine, a neurotransmitter in the brain, were found low in copper deficient animals. Low dopamine levels are common in human patients suffering from Parkinson's disease. Copper is an essential element in dopamine metabolism. Copper is required for the normal myelination of nerves. Myelin is a fatty substance that acts as insulation around nerves. When this insulation is missing, the material surrounding the nerves harden or sclerose. Therefore, abnormal neurological discharge results in spasticity, tremors, and paralysis.(TraceElements81) ELEVATED LEVELS OF MANGANESE Elevated levels have been found in patients with multiple sclerosis, learning disabilities and Parkinson's disease.(TraceElements117) Cobalt (Co) A deficiency of cobalt can result from low intake, poor absorption and high iron intake. Increased bacterial colonization of the small intestine is known to inhibit cobalt absorption as well as enteritis, and achlorhydria (lack of Intrinsic Factor). Parasites, particularly fish tape worms, selectively inhibit cobalt absorption. Medications may interfere with cobalt absorption such as colchicine, and neomycin. Symptoms of cobalt deficiency other than anemia include: Demylination Paresthesia of extremities Loss of joint-position sense Sore tongue Numbness in heels radiating to legs Abnormalities in cutaneous touch, pain, reflexes, and gait Dorsaal ndl ateracl olumnsa trophy Personality and mood swings Decreased vibratory sense Diarrhea Numbness in fingertips . radiating into arms Sharp pain in feet when head Is flexed anteriorly (Lhermitte's Sign) Some enzymes may be affected by cobalt deficiency such as alkaline phosphatase. Urinary methylmalonic acid and homocysteine may be increased due to a lack of cobalt activated enzymes L-methylmalonyl-CoA mutase and methionine senthetase. Hyperthyroidism apparently increases the requirement for this trace element. Cobalt is known to reduce thyroid activity and may prove beneficial in hyperthyroid conditions. Cobalt has been reported to lower blood pressure in hypertensive patients. Patients with neurological disease such as Parkinson's, multiple sclerosis and neuropsychiatric conditions have been reported to respond well to cobalt therapy. The response to supplementation was noted even though the patients showed no clinical signs of cobalt deficiency such as anemia. This indicates the effects of a subclinical cobalt deficiency.(TraceElements163-164) Vit D Supp: Jim Stephenson Jr: when asked: "I'm wondering why high doses of D3 is effective for ms sufferers? It's been proven to heal brain lesions from ms and in some cases ms sufferers who were unable to walk regains the ability to walk again" Answer: hey wax and wane in all sufferers, not just those on the protocol. It’s self reporting. Very short amount of time for any patient on it. Keep in mind webegan fortification in 1932. There’s still not ONE successful RCT. He uses the vaccine argument to not produce science from his work. They don’t care about their 1,25D level either. Insane!!! They measure 25D and take D3. Different analogues. And again they look in serum to see what folks have. If we really cared about D levels they would figure out a way to measure storage. Yes, 25D is the storage molecule but the tank is the liver not serum. Is your fuel in your car in the fuel line or the tank? And when someone took tons of D they would check urine like we do for protein. It’s what you DON’T see.........Never forget it’s also the most powerful naturally occurring steroid in the human body. It appears to me that the changes in MRI results among MS patients has nothing to do with the high dose D protocol. Apparently this is common absent Hormone D treatment as well. Such studies rely heavily on self reporting and let's NEVER forget these folks taking 100,000iu of D have 100+ serum levels of 1,25D. The most powerful naturally occurring steroid in the human body. And there's likely a pathogen occupying the VDR's so it will run amok. Conclusion "Vitamin D deficiency is not associated with thinning of RNFL or macular volume in MS eyes unaffected by ON. This finding suggests the role of vitamin D in modulating the severity of MS is not exerted through an influence on neurodegeneration." http://www.sciencedirect.com/.../pii/S2211034814000303 "Our work counters an emerging belief held in some quarters suggesting that higher levels of vitamin D can impact positively on brain health," says lead author Krystal Iacopetta, PhD candidate at the University of Adelaide. Based on a systematic review of over 70 pre-clinical and clinical studies, Ms Iacopetta investigated the role of vitamin D across a wide range of neurodegenerative diseases. "Past studies had found that patients with a neurodegenerative disease tended to have lower levels of vitamin D compared to healthy members of the population," she says. "This led to the hypothesis that increasing vitamin D levels, either through more UV and sun exposure or by taking vitamin D supplements, could potentially have a positive impact. A widely held community belief is that these supplements could reduce the risk of developing brain-related disorders or limit their progression." "The results of our in-depth review and an analysis of all the scientific literature however, indicates that this is not the case and that there is no convincing evidence supporting vitamin D as a protective agent for the brain," she says. Ms Iacopetta believes that the idea of vitamin D as a neuro-related protector has gained traction based on observational studies as opposed to evaluation of all the clinical evidence. "Our analysis of methodologies, sample sizes, and effects on treatment and control groups shows that the link between vitamin D and brain disorders is likely to be associative -- as opposed to a directly causal relationship," she explains. "We could not establish a clear role for a neuroprotective benefit from vitamin D for any of the diseases we investigated." https://www.sciencedaily.com/rel.../2018/07/180710101659.htm Find any real evidence that the low level is the cause, not a consequence. How ppl don’t see this is the WORST case of correlation equals causation is beyond me. This graph sums up the “scientific”part. Graph them, grouped by disease. Wave your wand and call the level the cause. VDD has never been proven to truly exist tied to the label HOLICK SOLD. Swap 25D for ANY other molecule. Let’s PLAY the BLAME GAME. Let go with rbc magnesium. Bet that makes a nifty chart too. 🤔🤔🤔 Please note how many you know that should have Rickets. Notice most of us should be dying. Look at the circled average of TWO COUNTRIES FFS. Image may contain: text
Muscle Contraction
Magnesium gives calcium permission to express itself and then it puts it right back into place. That's the regulatory role of calcium versus magnesium.
Myelin Sheath
Cholesterol is ESSENTIAL to make "Stress!" Hormones, myelin sheath in the brain and a THOUSAND other things that are KEY to your good health... The FAKE NEWS NARRATIVE that "Cholesterol is BAD for your Health" has officially been deemed a LIE by the Leading researchers & clinicians: https://bmjopen.bmj.com/content/bmjopen/6/6/e010401.full.pdf Cholesterol is your FRIEND... And when it RISES, it's a clinical sign of LOW Bioavailable Copper. THAT ^^^^ was proven by Leslie M. Klevay, MD, ScD in 1973 and has been REPEATEDLY proven by 30 Labs AROUND THE WORLD... One of the greatest SCAMS on the Planet is to be "fearful" of your Cholesterol levels... "A" votre sante! Tracey Reiche Fillmore Ease up on your carbs (sugars, esp.) and INCREASE your grassfed Beef Liver (Chock FULL of Bioavailable Copper) and enjoy the transition of BOTH your Triglycerides AND your HDL... Please KNOW that the LCAT enzyme to convert LDL >>HDL is dependent on Bioavailable Copper! (Feel free to share that PEARL with your myth-informed practitioner!... ;-) )
NAFLD - Non-Alcoholic Fatty Liver Disease
Fatty liver disease copper dishomeostasis Kristan Kershaw Animal liver is full of retinol, which is critical to your fatty liver healing... It is also full of bioavailable copper, magnesium, b vitamins including choline and a variety of other nutrients which are CRITICAL to healing. Eating fat, doesn't give you fatty liver... at least not 'real' fat versus manufactured fats. "Low" iron, diagnosed as anemia, is a warning sign of low bioavailable copper and retinol (vitamin A). Excess unbound iron in your body will lead to metabolic changes throughout every system in your body - BP and diabetes, fatty liver etc are all symptoms of that. NON-ALCOHOL FATTY LIVER DISEASE: results from a changed mineral composition in the liver & is the No.1 cause of cirrhosis (of the liver = calcification of the liver).
One Size Fits All approach...
Dale Morley: The reason this protocol suits "everyone" is because it panders to the body's chemistry - we ALL run on these minerals, vitamins and amino acids, omegas that can be found in abundance within the RCP. So whatever label your doctor wants to give your "disease" you can be sure that the root cause will be lack of mineral balance (as well as too many toxins). When your body is either lacking or imbalanced in some of the key minerals that Morley has identified ie iron, copper, magnesium - then your whole system can be out of kilter. As well as being integral to RBCs and that cycle, the RBC deliver oxygen to your cells (which I know you know), but the bit you might not be so clear about is that that oxygen is used by your mitochondria to create water or fuel for your body. There is a big continual "fight" between iron and magnesium to bind with the oxygen. You want it to be magnesium that wins to produce Mg-ATP which is your body's fuel and goes on to bind with the oxygen molecule at Complex V. Your mitochondria "run" on these minerals: magnesium, iron, sulphur, phosphate, copper and some B vitamins - it's a process of handling electrons (which come from your food) and get passed along a chain, the ETC it's called. So when you're tired, no energy etc it means your mitochondria aren't functioning well and they can go wrong and die (program cell death). Mitochondria have DNA too and if this gets damaged (lack of nutrients for example) then that damage will be replicated in the next cell. You end up "inviting" in all sorts of "diseases" including the biggies like heart disease or cancer. You have poor cell respiration basically. This protocol FEEDS your RBCs and Mitochondria because without them functioning well, it's downhill health wise. Your heart cells that are screaming out for magnesium contain the most mitochondria of any cells - why? Because they have a heck of a lot of work to do. Maybe up to 30,000 per cell. Minerals are absorbed in the small intestine and magnesium (that you were so low in), is a divalent mineral along with others like zinc, copper, manganese, iron, calcium. These minerals have the same method of absorption - they are shuttled into cells through a receptor (the divalent metal transporter, DMT-1) which are located on the cells of the duodenum. So, if you are low in one mineral, it's highly unlikely/not possible that all the others are in balance. Additionally, what "may" be happening in your cells is if you have too much iron stored in them (it shouldn't be there - 80% of your iron should be in circulation) what happens is the iron and its unpaired electrons cause Reactive Oxygen Species (ROS) - basically you're rusting! So all the ANTI-oxidents you consume within your diet like vitamin C or Vitamin E COULD be getting used up fighting this never ending oxidation. Now we all create ROS but the more rogue/unbound iron you have, the worse it gets. In my opinion, it could well be that you have too much iron in your cells/tissues/organs and that "fight" I mentioned above ^^ between magnesium and iron - well iron WON it in your heart cells (or some of them) because the SYMPTOM was arrthymia, but the ROOT CAUSE is too much iron/not enough magnesium/bioavailable copper.
Osteoporosis / Osteopenia
↑ Excess Iron = ↑ Oxidative stress = ↓ osteoblast regrowth = less bone density ↑ Excess, unbound iron = ↑ Estrogen = ↑ Iron stored into the Liver via Hepcidin + ↓ levels of Hemoglobin + Serum Fe. Osteoporosis is about Calcium LOSS (aka the “Simple LIE”), but it’s CAUSED by Excess, Unbound Iron (aka, the “Complex TRUTH!”)… The NOT-SO-FAKE-NEWS Research is VERY clear about Iron’s impact on Osteoblast activity (the Bone Building cells of the body!) and Iron’s ability to KILL Alkaline Phosphatase enzyme function & Osteoblasts, which are ESSENTIAL to make NEW Bone Matrix… Central to that process is the need for healthy & plentiful Bone Marrow. That REQUIRES lots of Retinol!… And Iron in the Bone has a unique way of RUSTING this Bone Marrow. Also ESSENTIAL to this KEY process of New Bone are Bioavailable Copper, Magnesium and about a dozen other key minerals, but Copper & Magnesium are at the head of the Stream because of their ability to activate Lysyl Oxidase and Alkaline Phosphatase enzymes, respectively. The ABSOLUTE worst thing you can to is take Synthetic, Supplemental Soy-based Hormone-D and Calcium Supplements. They are essentially poison to this vital bone-building process… Can this loss of bone mass be reversed?… Do you honestly think I would work THIS HARD to EDUCATE folks if ALL THIS NONSENSE were not reversible with the RCP?!?…. (And as I type out this response, maybe we should RENAME RCP to mean: “Reverse Chronic Processes…” Believe in the powers of RESILIENCE and RESTORATION that are endowed in a body that is properly nourished and NOT totally “Stressed Out with moronic deceit from the Internet… Osteoporosis is about Calcium LOSS (aka the "Simple LIE"), but it's CAUSED by Excess, Unbound Iron (aka, the "Complex TRUTH!")... The NOT-SO-FAKE-NEWS Research is VERY clear about Iron's impact on Osteoblast activity (the Bone Building cells of the body!) and Iron's ability to KILL Alkaline Phosphatase enzyme function & Osteoblasts, which are ESSENTIAL to make NEW Bone Matrix... Central to that process is the need for healthy & plentiful Bone Marrow. That REQUIRES lots of Retinol!... And Iron in the Bone has a unique way of RUSTING this Bone Marrow. Also ESSENTIAL to this KEY process of New Bone are Bioavailable Copper, Magnesium and about a dozen other key minerals, but Copper & Magnesium are at the head of the Stream because of their ability to activate Lysyl Oxidase and Alkaline Phosphatase enzymes, respectively. The ABSOLUTE worst thing you can to is take Synthetic, Supplemental Soy-based Hormone-D and Calcium Supplements. They are essentially poison to this vital bone-building process... Can this loss of bone mass be reversed?... Do you honestly think I would work THIS HARD to EDUCATE folks if ALL THIS NONSENSE were not reversible with the RCP?!?.... (And as I type out this response, maybe we should RENAME RCP to mean: "Reverse Chronic Processes..." ;-) ) Believe in the powers of RESILIENCE and RESTORATION that are endowed in a body that is properly nourished and NOT totally "Stressed Out with moronic deceit from the Internet... Have a blessed day! Cheers! [**It takes 7 years for your bones to be completely replaced by new cells... if it is fed correctly and has all the building blocks it needs.] Minerals, and RETINOL, aka REAL Vitamin-A... Copper and Magnesium are ORDERS OF MAGNITUDE more important than Calcium, esp. given the TWO KEY enzymes that they run: Lysyl Oxidase (knits collagen & elastin) and Alkaline Phosphatase, essential for Osteoblast activity... Retinol plays many roles, not the least of which is to nourish the Bone Marrow to produce the proper cells needed for NEW bone growth... And given Retinol's role to REGULATE Iron, this is KEY to curbing Iron's propensity to cause Oxidative Stress that KILLS Osteoblast activity... That ^^^^ is a VERY DIFFERENT story than the pablum in MOST internet articles and MOST conventionally trained practitioners... ** www.northmacschools.org/vimages/shared/vnews/.../Chapter%206-%20Bones.ppt But we're STILL missing a compelling citation... ;-) I've known for a looooong time that the body "turns over" every 7 yrs, but that's akin to a "wives tale..." It would be intriguing to see a more compelling citation to substantiate that widely accepted truth... Cheers! @Kathyrn Kemple-Mclaughlin... Found this: www.northmacschools.org/vimages/shared/vnews/.../Chapter%206-%20Bones.ppt But we're STILL missing a compelling citation... ;-) I've known for a looooong time that the body "turns over" every 7 yrs, but that's akin to a "wives tale..." It would be intriguing to see a more compelling citation to substantiate that widely accepted truth... Cheers! Some Causes: o grew up thinking that they were "Anemic?" o took Birth Control Pills?... o took Rx Meds for their Thyroids?... o took Bioidentical Hormones?... And is the youngest of those "six girls" more compromised than the oldest?... Just curious... Thanks! ...Susan Ferguson replied all- Sorry to hear that... My hypothesis, with NO data, is that your Mom was likely NOT properly mineralized before the FIRST birth, and gave up 10% of her mineral mass with each child... Oldest got 10%, 9%, 8%, 7%, 6%, & Caboose got 5%... It's not quite that stark, but close... And in the last tri-mester, the Mom is supposed to download 10X MORE Copper to the Fetus's Liver, than they will carry as an adult, to support their fledgling Immune System... Likely that #6 got only a WHISPER of Copper, and M$ is CAUSED by demyelination and LACK of Re-myelination of the nerve cells that causes an acceleration of Inflammation... Low Bioavailable Copper will CAUSE an increased storage of Iron in the Liver, the bones, other Organs and ultimately in the Brain... That's likely what's going on with those "six girls..." If you have periodontal disease, then you can bet that metabolically speaking, you have heart disease and osteoporosis - it may not be clinically noted, but it ALL is dependent on bioavailable copper being around to allow for the appropriate recycling, recovering and healing of these three areas. Bone density has nothing to do with calcium, and everything to do with iron overload building in the bone matrix. The process to make bones requires an enzyme called, Alkaline phosphotase, which requires Magnesium to work. It’s a very important enzyme which creates the environment for the osteoblasts (bone builders which need to be in an alkaline environment). Lysyl oxidase knits collagen and elastin together to really fuse the tissue. Lysyl oxidase requires bioavailable copper to function properly. Acid phosphotase is the medium of the Osteoclasts, which break down the bone matrix (and iron is fired up by acid phosphotase). The breakdown of bone by the osteoclasts causes calcium to be released into soft tissues. Only iron activates acid phosphotase to cause calcium loss from the hard tissues, and iron activates the enzymes to lay down the calcium into soft tissues into arteries, kidneys, gallbladder, bone spurs, etc. So, the key to healthy bones is keeping our unbound iron numbers in check, and providing our bones with adequate magnesium and bioavailable copper. Toxic Iron’s Role in Osteoporosis and Osteopenia. MJ HAMPSTEAD•SUNDAY, 6 AUGUST 2017 Morley Robbins: PLEASE STOP & PAY ATTENTION! Take the 15 min to read & UNDERSTAND the pioneering & penetrating research of J. Jian et al (2009): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821138/... The CAUSE of Osteoporosis is NOT LACK of Calcium or LOW Hormone-D or LOW Estrogen! IT IS EXCESS, UNBOUND IRON! (Please re-read that sentence, AGAIN, sloooooowly...) EVERYTHING your doctor "knows" about this "Bone Loss" is BASED ON A TOTAL LIE! And Kaye Gilligan has shared an IMPORTANT article -- please READ it! -- that highlights a team of researchers in New Zealand that have published equally pioneering & penetrating research in 2010, 2011, 2012, 2013, 2014, 2015, & 2016 that Calcium & Hormone-D supps, in response to Osteopenia or Osteoporosis, FOR A FACT CAUSES: o Increased Fractures... o Increased Heart Attacks... o NO CHANGE in Bone Density!... AGAIN, please re-read that last section ^^^^ above sloooooooooooooowly to FULLY understand the TRUTH!... The reason your years of taking Mg did NOT STOP this loss of bone density is that Mg -- acting ALONE-- only solves symptoms. It does NOT solve metabolic problems... Mg -- in concert w/ the Root Cause Protocol -- SOLVES THE ORIGIN OF THE PROBLEM: CopperIron Dysregulation... The ANSWER lies before you. I pray you have the peace of mind & the courage to do the RIGHT thing & NOT succumb to the Social Construction of Reality (I.e. your doctor, your neighbor, etc.) and take Calcium, Hormone-D or ANY OTHER HORMONE!!! They are NOT the answer... Not even close... The TRUTH is being spoken LOUD & CLEAR by Jian et al, as well as Bolland & Reid... I can NOT stress this enough! A votre sante!
Oxidation / Oxidative Stress -ITP 70
- “Accidents” with Oxygen that naturally occur in the body’s metabolism are called “Oxidants.” Another term is “Reactive Oxygen Species” (ROS). Over time, this causes “Rust”, which is Ferric Oxide, a combination of Iron & Oxygen. Excess, unbound Iron, causes “Rust”, which causes Inflammation. We know that new blood cells are made within the bone marrow (or the cascade of cell creation is started there at a minimum). We are learning today that when there is high oxidative stress as iron increases in the body, that the regeneration of bone cells (osteoblast regeneration) is reduced. What else do the osteoblasts need to carry out the repair and regeneration? Three KEY Ingredients: Retinol-A (Vitamin A). Bioavailable copper. Magnesium. Women: We have established above that there’s more Iron getting stored into many women’s livers and spleens from hormone imbalances, that with increased oxidative stress, there’s less osteoblast regrowth in the bones and less bone density… and now we are saying that retinol (vitamin a) intake from FOOD causes regeneration of bone marrow, reduction in the loading of iron in the spleen and liver, and increased cell production? What’s compounding these changes? “STRESSORS!” (from our VERY stressful modern day life, from the chemicals put into our bodies, food, inherited from our mothers/ grandmothers, from blue light bombardment, from expectations of mothers to be EVERYTHING to EVERYONE 24/7……..from excess, unbound IRON….. the never-ending process of creating Oxidative Stress keeps chugging it out!…) Back to our list… ↑ Excess, unbound Iron = ↑ Oxidative stress = ↓ Osteoblast regrowth = LESS bone density ↑ Excess iron = ↑ Estrogen = ↑ more Iron stored into the Liver via Hepcidin + ↓ Hemoglobin + Serum Fe ↑ Retinol-A (via food repletion) = ↑ bone marrow regeneration = ↑ Osteoblasts (maintain bone density) + ↑ new blood cells = ↑ Ferroxidase activity = ↓ Excess, unbound iron = ↓ Oxidative Stress Vitamin D, zinc and calcium supplementation – why aren’t these critical to bone strength as we keep getting told? We are already starting to see a picture on how come the RCP (Root Cause Protocol) ties in with reducing the chances of osteoporosis… reduce excess unbound iron, decrease oxidative stress via adrenal support and magnesium, increase bioavailable copper and retinol through food/whole food supplements, and we have our bases covered for the TRUE osteoporosis risk factors. SO how about the Vitamin D (Hormone-D!), K2, zinc and calcium side of things? These have been addressed – ad nauseum — by previous posts, but here’s a quick summary. – We get K2, zinc and calcium from eating an ancestral diet which is as wide and varied as possible. – We get Hormone-D from sunlight and foods such as eggs and cod liver oil (both great sources of retinol – who would have thought??). – Calcium carbonate supplements (most commonly suggested) require 12 steps to metabolize them into a form we can actually use. Other than many of the population not having the energy/mineral reserves to deal with that, many of us are going to grind to a halt (think cement = calcium) if calcium is supplemented from anything except food – Supplemental Hormone D kills retinol/retinoic acid in our liver, eyes (see iron toxicity post #62) and elsewhere in the body, preventing it from being able to facilitate cellular regeneration, repair and renewal…… leading to a WEAKENING in bone strength and repair. – Excess hepatic iron disrupts the 25(OH) enzyme (also mag dependent) – if we have excess iron in our liver….. and we don’t have enough magnesium…. we can’t carry out the transfer of Hormone D within the body – so it’ll test “low”. – What’s the biggest reason for insufficient zinc in the body? EXCESS unbound iron… – DID YOU KNOW: Magnesium from food and suggested supplemental sources helps the calcium to go where it’s needed? We need bioavailable copper (Evans et al, 1970) and retinol to synthesize ceruloplasmin – And it turns out that Retinol-A is ABSOLUTELY critical to loading that ^^^^ Copper to ensure Ferroxidase (FOX) enzyme function (Barber & Cousins, 1987) If we have INsufficient Retinol-A, and a LACK of Maggie and a LACK of Bioavailable Copper, what happens? We don’t have enough ferroxidase function, and we are faced with Iron that is DYSREGULATED and prone to ACT OUT!… What else happens when we don’t have enough ferroxidase function? We build up excess stored iron, yet apparent low blood Iron (because the body wants to protect us from the massive oxidative stress that HIGH or HIDING Iron in the blood represents)… our adrenals get stressed out… we start to get any number of metabolic “conditions” kicking in – hormonal imbalances, autoimmune conditions, diabetes, arthritis, depression, Alzheimer’s… our doctors spin us into a panic and dish out Mo’ Iron, Vitamin-D and any number of other medications which ONLY compound & confuse these conditions!… Now the way the RCP (Root Cause Protocol) looks at these things is dramatically different. Look at our EXPANDED list now! ↑ excess Iron = ↑ Oxidative Stress = ↓ Osteoblast regrowth = LESS bone density ↑ excess Iron = ↑ Estrogen = ↑ more Iron stored into the Liver via Hepcidin + ↓ Hemoglobin + Serum Fe ↑ Retinol (via food repletion) = ↑ Bone Marrow Regeneration = ↑ Osteoblasts (maintain bone density) + ↑ NEW blood cells = ↑ Ferroxidase enzyme function = ↓ Excess, unbound iron = ↓ Oxidative Stress ↑ Magnesium + Bioavailable Copper + Retinol-A = ↓ Oxidative Stress including ↓ Excess, unbound Iron = less chance of osteoporosis/osteopenia (AND the added bonus that Hormone-D will stabilize, too, in general!) What does all this REALLY MEAN? Just tell me HOW to reverse this osteoporosis risk…… The research behind the RCP (Root Cause Protocol) has always been encouraging the consumption of whole foods to obtain whole food vitamin c (to help with bioavailable copper), magnesium and adrenal support (to reduce stress on the body and provide important components for making Mg-ATP (energy)) and retinol (vitamin A)…. The research shared today is emphasizing that this is the right path, and that if you want strong bones, low risks of fractures, and to reduce the chance of getting osteoporosis. DO THE PROTOCOL! ¬ Reduce your oxidative stress (from food, physical/mental stress, get plenty of sleep, etc). ¬ Increase your retinol-A, Bioavailable Copper and Magnesium to give you more energy, reduce inflammation and give your body a chance to heal itself ¬ Release stresses of the past and emotions which may be holding you back from progressing. ¬ Reduce your iron load (when ready – support your body before donating blood!) RCP = ↓ oxidative stress + ↑ via Bioavailable Bopper, Mag, Retinol-A = ↓ Excess, unbound Iron = ↓ chance for osteoporosis AND better mineral flow throughout the body AS WELL AS ↑ positive health outcomes (= DEC ↓ “Stress!”) Let’s go with the SIMPLICITY of eating real food, whole food supplements and reducing “Stress!” in our life of ALL forms, rather than getting TOO LOST in the ENORMITY of the deception which has been around us on this and so many other topics we cover in this MAG FB Group!… The “D”eception is VERY REAL, but the effort to “fight it!” is simply NOT worth the expended MBR (Mag Burn Rate) associated with that effort!… So here’s to a Happy Mother’s Day to all of the Moms, Mums, Grannies, Grandmothers, etc. that have allowed us ALL to be here, to be apart of this grand experience called Planet Earth!… And most of all, thank you for the love & patience that you have shared and taught us, and may we enrich the lives of those around us – whether related or not — with the mineral truths & insights that are regularly being shared on this MAG FB Group… A votre sante! – Morley Robbins
Pancreatitis
Pancreatitis FOLLOWS Chronic Mg LOSS! As we learned yesterday, “ITIS” = “It’s The Iron, Seekers!” Depakote wastes magnesium - leads to pancreatitis Think this dynamic between K Channels & Iron Uptake MIGHT be important?!?... Activation of ATP-sensitive potassium channels enhances DMT1-mediated iron uptake in SK-N-SH cells in vitro https://www.nature.com/articles/srep33674?fbclid=IwAR21FdZ14Fm6oML_WcRnrxPmYaRQKOVKbwYTBkc4l1tdar8fSp1hk_KxuH4
Parkinson's - ITP: 14,54,61
Morley - Alzheimer's is high copper BUT it is still low ceruloplasmin. Alzheimer's and Parkinson's are on the opposite side of the spectrum with copper/ceruloplasmin metabolism. Alzheimer's is L iron and H copper in the hippocampus - serotonin gets oxidised. (high copper/ high ceruloplasmin = low bioavailable copper because most of the ceruloplasmin is the immuno reactive protein not the ferroxidase protein.) Parkinson's is H iron and L copper in the substantia nigra and dopamine gets oxidised. ( Low copper / Low ceruloplasmin = low bioavailable copper because copper and ceruloplasmin is low - again - we don't know how much of the ceruloplasmin contains the ferroxidase enyme or the immuno-reactive one ) RCP enables to help both cases - because it focuses on ceruloplasmin - increased ceruloplasmin aka ferroxidase, it can move the iron/copper out respectively. Condition associated with sympathetic dominance(TraceElementsIntro) We have found that patients who suffer from neurological disorders such as multiple sclerosis and Parkinson's disease, usually have a severe copper deficiency on their TMA tests. These observations have been reported by others. Douglas reported finding significant differences in hair copper levels in 40 multiple sclerosis patients compared to 42 control subjects. Similar findings have been observed in patients with Parkinson's disease. Animal studies have also confirmed a copper relationship to this condition. Levels of dopamine, a neurotransmitter in the brain, were found low in copper deficient animals. Low dopamine levels are common in human patients suffering from Parkinson's disease. Copper is an essential element in dopamine metabolism. Copper is required for the normal myelination of nerves. Myelin is a fatty substance that acts as insulation around nerves. When this insulation is missing, the material surrounding the nerves harden or sclerose. Therefore, abnormal neurological discharge results in spasticity, tremors, and paralysis.(TraceElements81) Researchers have found that an imbalance of iron to copper may play a role in Parkinson's disease as well as other neurological disorders. People who died of Parkinson's disease were found to have increased iron accumulation and low copper levels in areas of the brain that is affected in this condition. This excess iron has also been found in patients with ALS (amyotrophic lateral sclerosis) also known as Lou Gehrig's disease. Tissue damage caused by excess iron is due to its effect of generating free radicals or lipid peroxidation. Copper, on the other hand, protects from this type of free radical formation in neurological tissues. Iron and copper are closely related. Iron cannot be utilized by the body without adequate copper reserves. A person with a copper deficiency will retain iron because the body will stop eliminating it. ff this person also ingests large amounts of vitamin C, the iron overload will multiply further as vitamin C enhances iron absorption, while antagonizing copper absorption.(TraceElements111) ELEVATED LEVELS OF MANGANESE Elevated levels have been found in patients with multiple sclerosis, learning disabilities and Parkinson's disease.(TraceElements117) Cobalt (Co) A deficiency of cobalt can result from low intake, poor absorption and high iron intake. Increased bacterial colonization of the small intestine is known to inhibit cobalt absorption as well as enteritis, and achlorhydria (lack of Intrinsic Factor). Parasites, particularly fish tape worms, selectively inhibit cobalt absorption. Medications may interfere with cobalt absorption such as colchicine, and neomycin. Symptoms of cobalt deficiency other than anemia include: Demylination Paresthesia of extremities Loss of joint-position sense Sore tongue Numbness in heels radiating to legs Abnormalities in cutaneous touch, pain, reflexes, and gait Dorsaal ndl ateracl olumnsa trophy Personality and mood swings Decreased vibratory sense Diarrhea Numbness in fingertips . radiating into arms Sharp pain in feet when head Is flexed anteriorly (Lhermitte's Sign) Some enzymes may be affected by cobalt deficiency such as alkaline phosphatase. Urinary methylmalonic acid and homocysteine may be increased due to a lack of cobalt activated enzymes L-methylmalonyl-CoA mutase and methionine senthetase. Hyperthyroidism apparently increases the requirement for this trace element. Cobalt is known to reduce thyroid activity and may prove beneficial in hyperthyroid conditions. Cobalt has been reported to lower blood pressure in hypertensive patients. Patients with neurological disease such as Parkinson's, multiple sclerosis and neuropsychiatric conditions have been reported to respond well to cobalt therapy. The response to supplementation was noted even though the patients showed no clinical signs of cobalt deficiency such as anemia. This indicates the effects of a subclinical cobalt deficiency.(TraceElements163-164) Iron can accumulate in free form in any body tissue under conditions of iron overload. That is why iron excess causes such a wide variety of illnesses. The most dangerous feature of iron is that it is attracted to, and deposits in, damaged tissue. Thus, the neurofibrillary tangles of Alzheimer’s, the substantia nigra of Parkinson’s, the atherosclerotic plaques of coronary artery disease, the inflamed joints of arthritis, the pancreatic islet cells of adult-onset diabetics all display increased levels of free iron. There is no way to tell whether the iron initiates the disease or if the diseased tissue attracts the iron which then exacerbates the condition. But either way, free iron in any body tissue is dangerous (Iron The Most Toxic Metal 19) • Neurological Degeneration: Parkinson’s & Alzheimer’s o The brain is a major target for excess iron. Accumulation of iron in brain tissue either causes, or contributes to, neurological diseases such as Parkinsonism and Alzheimer’s disease. Brain and nerve tissue iron accumulation is now recognized as a cardinal feature of most, if not all, neurodegenerative diseases. It is still uncertain whether excess iron in the substantia nigra is a cause of Parkinson’s, or if it is a secondary factor that accelerates nerve damage.(Iron—The Most Toxic Metal 18,20,67,69) Research Article: Activation of ATP-sensitive potassium channels enhances DMT1-mediated iron uptake in SK-N-SH cells in vitro Xixun Du, Huamin Xu, Limin Shi, Zhifeng Jiang, Ning Song, Hong Jiang & Junxia Xie Scientific Reports volume 6, Article number: 33674 (2016) | Download Citation Abstract Iron importer divalent metal transporter 1 (DMT1) plays a crucial role in the nigal iron accumulation in Parkinson’s disease (PD). Membrane hyperpolarization is one of the factors that could affect its iron transport function. Besides iron, selective activation of the ATP-sensitive potassium (KATP) channels also contributes to the vulnerability of dopaminergic neurons in PD. Interestingly, activation of KATP channels could induce membrane hyperpolarization. Therefore, it is of vital importance to study the effects of activation of KATP channels on DMT1-mediated iron uptake function. In the present study, activation of KATP channels by diazoxide resulted in the hyperpolarization of the membrane potential and increased DMT1-mediated iron uptake in SK-N-SH cells. This led to an increase in intracellular iron levels and a subsequent decrease in the mitochondrial membrane potential and an increase in ROS production. Delayed inactivation of the Fe2+-evoked currents by diazoxide was recorded by patch clamp in HEK293 cells, which demonstrated that diazoxide could prolonged DMT1-facilitated iron transport. While inhibition of KATP channels by glibenclamide could block ferrous iron influx and the subsequent cell damage. Overexpression of Kir6.2/SUR1 resulted in an increase in iron influx and intracellular iron levels, which was markedly increased after diazoxide treatment.https://www.nature.com/articles/srep33674?fbclid=IwAR21FdZ14Fm6oML_WcRnrxPmYaRQKOVKbwYTBkc4l1tdar8fSp1hk_KxuH4 So what we are saying here is that Mg is most likely the main reason why potassium/calcium channels/pathways are blocked or sluggish. Since all ATP is actually Mg-ATP we start to get more proof that low magnesium can impede other areas of biology that Mg was never thought to have an active role in. Tyrosine, natural amino acid. Tyrosine undergoes a chemical reaction in the body and helps make both dopamine and thyroid hormone. CoQ10 Folate B9, (lack of causes Homocysteine -elevated a problem for Parkinson’s. (Problems with methylation) Glutathione AVOID nitrites (peroxynitrites) Levodopa is a major drug mugger. parkinsons - science news article Dec 8 2019 - parkinsons connected to gut dysbiosis - people who have appendix removal never get parkinsons - chart connects the gut to the base of the brain via vagus nerve - balance in the gut between lactobacillus and coli - retinol on board lacto in proper ratio, w/o retinol, ecoli takes over Consales et al, 2012, “Electromagnetic Fields, Oxidative Stress, and Neurodegeneration” https://www.hindawi.com/journals/ijcb/2012/683897/citations/ Please note that the 1st study noted ^^^^ (Maaroufi et al, 2014) is a very provocative one that chose to combine EMFs (900 MHz) with Iron loading on the experimental rodents… The sentence that REALLY caught my “eye,” (pardon the pun…) was the following: “A link between EMF, iron accumulation in the brain and neurodegenerative disorders including Parkinson’s and Alzheimer’s diseases has been suggested.”
Parkinson's - ITP: 14,54,61
Alzheimer's is high copper BUT it is still low ceruloplasmin. Alzheimer's and Parkinson's are on the opposite side of the spectrum with copper/ceruloplasmin metabolism. Alzheimer's is L iron and H copper in the hippocampus - serotonin gets oxidised. (high copper/ high ceruloplasmin = low bioavailable copper because most of the ceruloplasmin is the immuno reactive protein not the ferroxidase protein.) Parkinson's is H iron and L copper in the substantia nigra and dopamine gets oxidised. ( Low copper / Low ceruloplasmin = low bioavailable copper because copper and ceruloplasmin is low - again - we don't know how much of the ceruloplasmin contains the ferroxidase enyme or the immuno-reactive one ) RCP enables to help both cases - because it focuses on ceruloplasmin - increased ceruloplasmin aka ferroxidase, it can move the iron/copper out respectively. Condition associated with sympathetic dominance(TraceElementsIntro) We have found that patients who suffer from neurological disorders such as multiple sclerosis and Parkinson's disease, usually have a severe copper deficiency on their TMA tests. These observations have been reported by others. Douglas reported finding significant differences in hair copper levels in 40 multiple sclerosis patients compared to 42 control subjects. Similar findings have been observed in patients with Parkinson's disease. Animal studies have also confirmed a copper relationship to this condition. Levels of dopamine, a neurotransmitter in the brain, were found low in copper deficient animals. Low dopamine levels are common in human patients suffering from Parkinson's disease. Copper is an essential element in dopamine metabolism. Copper is required for the normal myelination of nerves. Myelin is a fatty substance that acts as insulation around nerves. When this insulation is missing, the material surrounding the nerves harden or sclerose. Therefore, abnormal neurological discharge results in spasticity, tremors, and paralysis.(TraceElements81) Researchers have found that an imbalance of iron to copper may play a role in Parkinson's disease as well as other neurological disorders. People who died of Parkinson's disease were found to have increased iron accumulation and low copper levels in areas of the brain that is affected in this condition. This excess iron has also been found in patients with ALS (amyotrophic lateral sclerosis) also known as Lou Gehrig's disease. Tissue damage caused by excess iron is due to its effect of generating free radicals or lipid peroxidation. Copper, on the other hand, protects from this type of free radical formation in neurological tissues. Iron and copper are closely related. Iron cannot be utilized by the body without adequate copper reserves. A person with a copper deficiency will retain iron because the body will stop eliminating it. If this person also ingests large amounts of ascorbic acid, the iron overload will multiply further as ascorbic acid enhances iron absorption, while antagonizing copper absorption.(TraceElements111) ELEVATED LEVELS OF MANGANESE Elevated levels have been found in patients with multiple sclerosis, learning disabilities and Parkinson's disease.(TraceElements117) Cobalt (Co) A deficiency of cobalt can result from low intake, poor absorption and high iron intake. Increased bacterial colonization of the small intestine is known to inhibit cobalt absorption as well as enteritis, and achlorhydria (lack of Intrinsic Factor). Parasites, particularly fish tape worms, selectively inhibit cobalt absorption. Medications may interfere with cobalt absorption such as colchicine, and neomycin. Symptoms of cobalt deficiency other than anemia include: Demylination Paresthesia of extremities Loss of joint-position sense Sore tongue Numbness in heels radiating to legs Abnormalities in cutaneous touch, pain, reflexes, and gait Dorsaal ndl ateracl olumnsa trophy Personality and mood swings Decreased vibratory sense Diarrhea Numbness in fingertips .radiating into arms. Sharp pain in feet when head Is flexed anteriorly (Lhermitte's Sign) Some enzymes may be affected by cobalt deficiency such as alkaline phosphatase. Urinary methylmalonic acid and homocysteine may be increased due to a lack of cobalt activated enzymes L-methylmalonyl-CoA mutase and methionine senthetase. Hyperthyroidism apparently increases the requirement for this trace element. Cobalt is known to reduce thyroid activity and may prove beneficial in hyperthyroid conditions. Cobalt has been reported to lower blood pressure in hypertensive patients. Patients with neurological disease such as Parkinson's, multiple sclerosis and neuropsychiatric conditions have been reported to respond well to cobalt therapy. The response to supplementation was noted even though the patients showed no clinical signs of cobalt deficiency such as anemia. This indicates the effects of a subclinical cobalt deficiency (TraceElements163-164) Iron can accumulate in free form in any body tissue under conditions of iron overload. That is why iron excess causes such a wide variety of illnesses. The most dangerous feature of iron is that it is attracted to, and deposits in, damaged tissue. Thus, the neurofibrillary tangles of Alzheimer’s, the substantia nigra of Parkinson’s, the atherosclerotic plaques of coronary artery disease, the inflamed joints of arthritis, the pancreatic islet cells of adult-onset diabetics all display increased levels of free iron. There is no way to tell whether the iron initiates the disease or if the diseased tissue attracts the iron which then exacerbates the condition. But either way, free iron in any body tissue is dangerous (Iron The Most Toxic Metal 19)• Neurological Degeneration: Parkinson’s & Alzheimer’s o The brain is a major target for excess iron. Accumulation of iron in brain tissue either causes, or contributes to, neurological diseases such as Parkinsonism and Alzheimer’s disease. Brain and nerve tissue iron accumulation is now recognized as a cardinal feature of most, if not all, neurodegenerative diseases. It is still uncertain whether excess iron in the substantia nigra is a cause of Parkinson’s, or if it is a secondary factor that accelerates nerve damage.(Iron—The Most Toxic Metal 18,20,67,69) Research Article: Activation of ATP-sensitive potassium channels enhances DMT1-mediated iron uptake in SK-N-SH cells in vitro Xixun Du, Huamin Xu, Limin Shi, Zhifeng Jiang, Ning Song, Hong Jiang & Junxia Xie Scientific Reports volume 6, Article number: 33674 (2016) Abstract: Iron importer divalent metal transporter 1 (DMT1) plays a crucial role in the nigal iron accumulation in Parkinson’s disease (PD). Membrane hyperpolarization is one of the factors that could affect its iron transport function. Besides iron, selective activation of the ATP-sensitive potassium (KATP) channels also contributes to the vulnerability of dopaminergic neurons in PD. Interestingly, activation of KATP channels could induce membrane hyperpolarization. Therefore, it is of vital importance to study the effects of activation of KATP channels on DMT1-mediated iron uptake function. In the present study, activation of KATP channels by diazoxide resulted in the hyperpolarization of the membrane potential and increased DMT1-mediated iron uptake in SK-N-SH cells. This led to an increase in intracellular iron levels and a subsequent decrease in the mitochondrial membrane potential and an increase in ROS production. Delayed inactivation of the Fe2+-evoked currents by diazoxide was recorded by patch clamp in HEK293 cells, which demonstrated that diazoxide could prolonged DMT1-facilitated iron transport. While inhibition of KATP channels by glibenclamide could block ferrous iron influx and the subsequent cell damage. Overexpression of Kir6.2/SUR1 resulted in an increase in iron influx and intracellular iron levels, which was markedly increased after diazoxide treatment. https://www.nature.com/articles/srep33674 fbclid=IwAR21FdZ14Fm6oML_WcRnrxPmYaRQKOVKbwYTBkc4l1tdar8fSp1hk_KxuH4. So what we are saying here is that Mg is most likely the main reason why potassium/calcium channels/pathways are blocked or sluggish. Since all ATP is actually Mg-ATP we start to get more proof that low magnesium can impede other areas of biology that Mg was never thought to have an active role in. Tyrosine, natural amino acid. Tyrosine undergoes a chemical reaction in the body and helps make both dopamine and thyroid hormone. CoQ10. Folate B9, (lack of causes Homocysteine -elevated a problem for Parkinson’s. (Problems with methylation) Glutathione. AVOID nitrites (peroxynitrites) Levodopa is a major drug mugger. Parkinsons - science news article Dec 8 2019 - parkinsons connected to gut dysbiosis -people who have appendix removal never get parkinsons- chart connects the gut to the base of the brain via vagus nerve- balance in the gut between lactobacillus and coli - retinol on board lacto in proper ratio, w/o retinol, ecoli takes over Consales et al, 2012, “Electromagnetic Fields, Oxidative Stress, and Neurodegeneration”
https://www.hindawi.com/journals/ijcb/2012/683897/citations/ Please note that the 1st study noted ^^^^ (Maaroufi et al, 2014) is a very provocative one that chose to combine EMFs (900 MHz) with Iron loading on the experimental rodents…The sentence that REALLY caught my “eye,” (pardon the pun…) was the following:
“A link between EMF, iron accumulation in the brain and neurodegenerative disorders including. Parkinson’s and Alzheimer’s diseases has been suggested.”
Periodontal Disease
If you have periodontal disease, then you can bet that metabolically speaking, you have heart disease and osteoporosis - it may not be clinically noted, but it ALL is dependent on bioavailable copper being around to allow for the appropriate recycling, recovering and healing of these three areas.
PMS
What’s important to know is that Zinc in a woman’s body is a surrogate for Progesterone, and Copper is a surrogate for Estrogen. And as a woman’s cycle progresses, the Estrogen spike is followed by a spike in Progesterone. So when we are “Stressed Out!” we know that the Mg is low, and thus the Mg-ATP is low, so then the binding of Copper slows down or stops. What’s important to understand is that “unbound” Copper is essentially a “Heavy Metal” in the body without its protein. This bio-unavailable form then collects in our Adrenals, our Liver and the Limbic region of our Brain. Why is that last point so important, from what I’ve read, as the spike moves from Estrogen to Progesterone dominance, this releases Copper in the brain and compounds the emotions during this point of the cycle. So, yes, there is a Copper/Zinc dynamic, but once again, Maggie’s in the middle!… If you suffer from PMS, please take Mo’ Maggie. Also, you may enjoy this wonderful article written by Guy E. Abraham, MD and Ruth E. Rumley, MD explaining the dynamics of PMS and Magnesium deficiency. http://www.mgwater.com/gapmts.shtml
Potassium
Potassium is a critical electrolyte which is often low as a part of an ongoing stress response. It goes that way after extended pressure on the adrenals....Mag and potassium are certainly related but it’s not necessarily potassium causing low mag. It’s a two-way street. Underpinning low potassium is likely low retinol and magnesium, plus low bioavailable copper, which stems from dysregulation between iron and everything else in the body 😉
Potassium
Potassium is a critical electrolyte which is often low as a part of an ongoing stress response. It goes that way after extended pressure on the adrenals....Mag and potassium are certainly related but it’s not necessarily potassium causing low mag. It’s a two-way street. Underpinning low potassium is likely low retinol and magnesium, plus low bioavailable copper, which stems from dysregulation between iron and everything else in the body
Pregnancy
From Morley "Calling ALL Moms & Moms-to-be! Please READ this article sloooooowly & carefully! https://onlinelibrary.wiley.com/.../j.1365-2826.2008.01658.x Now, here's the TEST: If your Birthing practitioner: 1) isn't AWARE of this important study... 2) can't EXPLAIN its PROFOUND significance... 3) doesn't KNOW what Ferroxidase enzyme function is... 4) doesn't KNOW what Zyklopen (Eleutherin) is... 5) doesn't KNOW that REDUCED Ferroxidase function affects Iron transfer btwn Mother & Child AND CAUSES Placental Inclusions, which are KNOWN to CAUSE Autism... then maybe you need a MORE enlightened, & minerally-savvy birthing practitioner like Mandy Chadwick... And be sure to ask your birthing practitioner about the STUNNING research re maternal hemoglobin that is SUPPOSED TO FALL in the 2nd half of the pregnancy (Steers, 1995). BeLIEving that Iron, as expressed by Hgb, needs to rise is what: o CAUSES Metabolic Confusion, for Mother & child... o CAUSES pregnant women to take Iron supplements... o CAUSES Zyklopen enzyme to NOT function properly... o CAUSES a meteoric rise in Autism rates that are now 1 in 35... Sadly, this mineral & metabolic dynamic is NOT Rocket Science.... And if your birthing practitioner THINKS IT IS, then I would STRONGLY advise you to RE-THINK who you are entrusting your life & your newborn's life to... Strong words ^^^^, but they are based on sound, solid, scientific evidence!!! It's time women STEP UP to the TRUTH of the CopperIron dynamic in Pregnancy... A votre sante!" Low Hb in pregnancy. From Morley. Before commenting on your notable numbers, can you provide some answers to these questions?... o Prior to your pregnancy, did you have any health issues or mineral imbalances that you were aware of?... o Is this your 1st Pregnancy, or have there been others?... o In addition to the supplements that you noted, have you been taking any Prenatals?... o What was your Hemoglobin at the START of your Pregnancy, and PRIOR to your pregnancy?... The process of Hemodilution LOWERS the Hgb, and yours is very much in alignment with the Research of 150,000 Live Births by Philip Steer, MD who found that the healthiest babies were born to Mom's who's Hgb was between 8.5-9.5 (Steer, 1995) which is well below the norms in the world of conventional OB today... And here's a more recent study that CLEARLY indicates the Ferritin levels are INVERSELY correlated with the weight of the baby and the LAST SENTENCE of this Abstract needs to be factored in VERY carefully: https://academic.oup.com/humrep/article/15/8/1843/670873 MORE Iron is NOT always the answer... I'd welcome your answers to those questions before commenting further... "A" votre sante!
Pre-Diabetes or tendency toward diabetes
signs of symptoms of diabetes, which is poor sugar handling, which is poor copper metabolism. It's not an insulin issue necessarily. It's a copper issue.
Probiotics
Cathy Thelen We recommend Digest Basic and GutPro are recommended. Morley says " I’m all for taking Probiotics, but for the right reasons — they help us with our Magnesium uptake!....we’re being told to up our Probiotics to bring more “good” bacteria into our gut, so that it can offset the “bad” bacteria known as TMAO. This you may recall was the subject of a recent study linking elevated levels of TMAO to red meat — yet another attempt to keep us from eating the best source of CoQ10, L-Carnitine and D-Ribose on the Planet. (Those 3 nutrients + Mg are the core elements for cardiac energy production…)....." We need to be rebalancing out Minerals with The RCP for optimal gut health. -Moderator/Root Cause Protocol Consultant Jen Fokkens Another thing to remember is the DE is gram positive and the bad gut bacteria is gram negative. Thus the DE attracts the gram negative bad bacteria and sends them packing and so helps the gut flora to flourish. I’m not intimating that probiotics are not necessary but that the DE is very helpful. Fermented foods are encouraged.
Pyroluria
Per Morley Robbins Here's my letter to a client challenging the conventional treatment of Pyroles... I'll look forward to the "blow back!"Pursuant to our discussion, I'm attaching a link that explains the METABOLIC ORIGIN of Pyroluria:https://pyroluriatesting.com/about-us/ What is very relevant is their assertion on Page 2 that:"Any source of oxidative stress can elevate urinary pyrrole levels. Many persons have elevated pyrroles resulting from factors such as physical accidents, illnesses, infections, emotional trauma and toxic metals."This is a MAJOR TILT!... It's very important to understand that chronic "Stress!" will result in elevated levels of ACTH (key "Stress!" hormone, and that will result in STOPPING the production of Ceruloplasmin (Cp) in the Liver, which then undermines the bioavailability of Copper. Given that Copper plays a pivotal role in giving the Anti-Oxidant Defense pathway its potency (via the key antioxidant enzymes SOD, and Catalase), the WORST thing you could do would be to "DROWN" the body in Zinc, as that will only PREVENT Copper absorption and undermine the body's ability to mobilize an appropriate and consistent anti-oxidant response.http://www.ncbi.nlm.nih.gov/pubmed/16112185 (Copper is THE key mineral for optimal anti-oxidative potency...)The added insult is their assertion that Pyroluria is a: "chemical imbalance involving an abnormality in hemoglobin synthesis." What they FAIL to indicate is HOW IMPORTANT bioavailable Copper is to the optimal synthesis of hemoglobin.http://www.ncbi.nlm.nih.gov/pubmed/16406711 (Ferrochelatase, the rate-limiting enzyme to MAKE Hemoglobin will NOT work without Copper...)In my world, the focus should be to CORRECT the Copper dysregulation, and NOT TREAT the symptoms that result from "Stress!"... In a word, this approach to "Pyrroluria" is just more "Affagato!
Pyrolles
Pyrolles Too bad Walsh trained practitioners don't see or understand this basic physiological FACT!... Pyrroles are CAUSED by LOW bioavailable Copper not able to properly fire up Ferrochelatase enzyme, that leads to defective Heme, that THEN eats up Zn & B6. Drowning someone w/ Zn & B6 addresses the "Symptoms" BUT DOES NOTHING to correct the underlying physiology, nor TRUE mineral deficiency... Allopathetic medicine is RIDDLED w/ this same kind M.oronic D.ogma that is Idiopathic, at best! A votre sante! Zinc depletes both copper and ceruloplasmin. Copper and ceruloplasmin are REQUIRED to make heme and also REQUIRED to load heme onto hemoglobin so that the hemoglobin can function properly. Copper and ceruloplasmin are also REQUIRED for copper dependent enzymes such as SOD which are powerful antioxidants which help to reduce oxidative stress. Both copper and ceruloplasmin are REQUIRED for the immune system function. Both copper and ceruloplasmin are REQUIRED to regulate iron and prevent iron oxidation/oxidative stress. "Pyroluria" is actually caused by oxidative stress, which can be caused by stress, accidents, injury, iron and copper dysregulation, etc.. Magnesium is also required. Giving zinc is only treating a symptom of "pyroluria" while in fact, making the underlying oxidative stress much worse. Zinc may make the person feel better temporarily, however, it will not solve the underlying issues. In order to treat the CAUSE of the "pyroluria" you must not use zinc, unless for very short periods of time and in very small amounts and also balanced with copper and other minerals. Morley has a much better understanding of how to deal with oxidative stress in the body. QThe 1948 Classic was "1984!"... What is Black is White... What is White is Black... FACT: ALL Facets of Iron metabolism requires bioavailable Copper... FACT: Efficient production of RBCs REQUIRES bioavailable Copper... FACT: Inefficient RBC production creates kryptopyrroles that affect Zn & B6 status... FACT: Zn supplements BLOCK Copper absorption... And now we find MANY are being told to take Zinc & B6 to address their symptoms, but NOWHERE is there any mention of Copper to SOLVE THE PROBLEM! What is Black is White... What is White is Black... We are 30+ yrs Post-1984! And sadly, the Masses remain asleep & afraid to STOP this twisted & wrong nutritional approach... A votre sante! Pyrroles are made when Hemoglobin can't be properly made... That ^^^^ ENTIRE process is driven by bioavailable Copper, esp. the last AND rate-limiting step where Ferrochelatase enzyme inserts an Iron atom into the center of the protoporphyrin ring... (That enzyme DON'T work without Copper!) Following the conventional Tx is utter nonsense as the influx of XS Zinc will KILL the absorption of essential Copper & thus PREVENT the optimal production of Ceruloplasmin by the Liver... (Likely the objective of that flawed Tx... ;-( ) I would advise you re-think this Post to avoid adding FURTHER confusion to this metabolic event that occurs ONLY in bodies desperately LOW in Ceruloplasmin... A votre sante!" Unlike · Reply · 12 · Yesterday at 3:47am Here are bits of a comment I wrote earlier about it: Hemoglobin = a transport molecule for transporting oxygen in the blood of vertebrates. (Suffix -in usually denotes a protein.) Heme = an iron-containing compound of the porphyrin class that forms the nonprotein part of hemoglobin and some other biological molecules. Globin = the type of protein we see in hemoglobin (there are other places globin is used) Pyroluria and pyrroles result from improper heme synthesis - they actually are parts of heme that seem to not be properly constructed when there is some issue constructing heme in the body, and those pyrroles are what cause the symptoms called "pyroluria."
Reflux
What is acid reflux? Why does someone get it? Https://www.facebook.com/groups/388392151228860?view=permalink&id=1648271008574295 What is acid reflux? Why does someone get it? I bet it's not the first thing that comes to your mind... There have been lots of posts lately (& many in the past too) about reflux... about digestive challenges... treatments for reflux in adults and even kids... I'd like to bring everyone's attention to WHY this happens. Anyone who has been around here for a while will know that iron is underlying it... but how? Why does it affect some and not others? The latter of these questions, nobody can say for certainty as there's so many variables... the first couple - WHY and HOW... that I can do. I'd suggest getting yourself a cup of tea, or an adrenal cocktail (depending on your timezone!) and have a read... Acid reflux comes from several angles, but they are all related...even if it doesn’t seem that way. Stress causes magnesium loss and that leads to mineral dysregulation. Most of us have had mineral dysregulation our whole lives (even when we didn’t know it - as kids, or as a generational ‘gift’ from our mothers). When we don’t have enough of the right minerals, minerals don’t flow through our bodies and the body goes into a ‘backup mode’ of sorts - trying to keep homeostasis (the body in some level of balance), but with limited resources, so over time, things don’t work as they “should”. One of those things is stomach acid creation. If we don’t have enough stomach acid, then we reduce the effectivity of our digestion. We don’t absorb as much of the nutrients we need, and that leads to more nutritional deficiencies. It also leads the way for iron to be deposited in the digestive system (there are step in the RCP specifically to help increase stomach acid which are tied in with this angle!)... Iron in the lower digestive system contributes significantly to leaky gut (see Morley’s post #68 to understand that statement some more!!), which means more oxidative stress in the body, less nutrients available in the body and generally the body working harder to deal with food components in the blood that should have been broken down into amino acids, fats and other components in the gut, before entering the blood! Histamine levels rise along the way, which leads to the loss of more mag and bioavailable copper. People get more sensitive to foods, to their environment and don’t cope with stress as well. In the process, they often would also have other challenges - lots of weight gain. Loss of weight, SIBO due to overgrowth of the wrong bugs in the gut (stomach acid is a presenter of that!!). More stress. More loss of mag and important other components. More iron sets into stores in the liver and other organs. Less places for the components that should be there. Adrenals by now have been working overtime for a long time. They can’t cope. The thyroid goes in as a ‘backup’ and eventually will show signs of not working well. Modern society tells us that butter and salt are bad, or the individual may not digest the fats well as their gall bladder is sludged up with iron and is maybe causing pain or impaired digestion. Again, fats are needed here, as well as B vitamins and other nutrients. The body hasn’t been making or absorbing these nutrients for a while now. Potassium and sodium are often low care of cultural things (“low salt x y z, it’ll raise your BP didn’t you know???!!!”). The adrenals then suffer even more because mag is so low, the electrolytes are bottomed out and the body is losing options. Potassium is needed for the sphincter at the top of the stomach. Magnesium too. There’s not enough stomach acid, so food sits for longer and then doesn’t get broken down and the sphincter isn’t working well, so reflux gets worse, food options which don’t cause pain, reduce. Which then perpetuates the reason for the reflux in the first place! Mag loss and then impaired nutrient absorption. By this stage the individual is desperate and gets more help than the over the counter reflux measures. Doctor says it’s time for reflux meds, which give relief, but make the magnesium deficiency worse, hinder food absorption even more as it sits longer in the stomach, and eventually that stops working, or the person feels worse and stops, but just continues with the pain or ‘making do’ with changed diet and adjustments to lifestyle to manage symptoms. The root cause protocol will help to reduce this cycle and help improve all aspects discussed above to be a positive loop of improvement, not this ridiculous negative spiral out of control. Https://therootcauseprotocol.com/ Please look at the WHOLE of the RCP and work with a consultant to get the full picture. https://therootcauseprotocol.com/get-help/ Invest the money in your long term health and not in band aid solutions. - Admin/Root Cause Protocol Consultant Development Manager ( #rcpconsultant #moderator #reflux #rcpfacts - to help with searches!)
Restless Leg Syndrome (RLS)
Morley - Again, folks, we need to come back to the ROOT CAUSE of the Magnesium LOSS that then TRIGGERS the Potassium LOSS that begets the label "Restless Legs Syndrome" (RLS)... And the REAL reason is.... Wait for it... "D"rum Roll, please... EXCESS, UNBOUND IRON that hangs out in the myoglobin of the muscle cells. And if you're LOW on Bioavailable Copper -- AS MOST MAG-pies & MAG-nets ARE -- you will get the characteristic "twitching" that ONLY excess, unbound Iron can cause... (Think of it as "Parkinson's" in your legs...) Make sense?.. RESTLESS LEG SYNDROME: neuronal issue – starts in brain but takes place in legs. It is basically the neurons in the brain & muscles reacting to too much iron & thereby effecting Mg status. The main concentration of Fe is in Hgb & Mgb (huge) & in RLS we are witnessing a rusting of the communications in the muscle tissues which originates in brain. Classic form of oxidative stress. Responds well to Mg supplementation normally & sometimes it pays to dig deeper into the CuFe dysregulation which is underlying. Most people on the RCP find that the whole protocol in general helps to alleviate the issue. (unknown author). AC helps many with this issue
The Reticuloendothelial System (RES) -
The "Iron Recycling System" inside our body provides 95% of our daily Iron needs. In total, we use ~25mg of Iron per day to make new Red Blood Cells and other Iron-based proteins, such as Heme. So 24mg out of 25mg come from the Iron in our body already thanks to this “recycling system” (RES). Which means, we ONLY need need to intake ~1mg per day from food to balance the ~1mg we excrete in our feces each day. RES is dependent upon Bioavailable Copper to ensure proper Iron “recycling.” There are three key cells involved in RES: 1) Enterocytes - digestive cells in our intestines 2) Hepatocytes - the main cells in our liver 3) Macrophages - the KEY “Pac Men” that serve as first responders and recyclers
Retinol
There is a critical importance of Retinol in our bodies to help get the body moving Iron where it needs to go, getting our Bioavailable Copper increased, and so much more. Retinol is REAL Vitamin-A... Beta Carotene is a JOKE. It takes 12 Beta-carotenes + Energy + Beta-carotene 15-15'monooxygenase (Copper dependent, mind you...) to make ONE Retinol... An important metabolic function LOST ON THE WORLD OF CONVENTION is that Retinoic Acid is what LOADS Copper into the Ceruloplasmin protein so that it can express the Ferroxidase enzyme function... Naturally occurring, wholefood Vitamin A found in Cod Liver Oil, Beef Liver, Grassfed Butter, and other animal-based foods. Retinol is vital for “loading” Copper into Ceruloplasmin, which makes Copper become bioavailable (aka. “increasing Ferroxidase” activity) so that it can then “regulate” Iron as needed across and around the body, and stop Oxidative Stress (aka. “rust”). (Download RCP Instruction Manual here to get recommendations for brands of Cod Liver Oil, Beef Liver, etc…)
Rheumatoid Arthritis
is generally an overall low Fe status (anemia) but by contrast, Fe is elevated in the synovial fluid of arthritic joints suggesting a significant derangement of Fe metabolism (unknown author) Fluid builds in tissues=Copper iron dysregulation From The Iron Elephant: Untreated Iron Overload Can Give You Arthritis Sore or stiff fingers with affection of the index and middle finger is typical of iron overload. However it can vary depending on overuse and straining. Do test for iron load if it hurts when someone shakes your hand and the pain lingers. Other joints that may get affected include knees, hips, jaw, shoulder. The most frequently affected are the hands and wrists and weight-bearing joints such as knees. Joint pain is not always present. Dupuytren’s contracture – which is a proliferative connective tissue disorder which involves the palmar fascia of the hand – is sometimes seen. In severe cases, the hand takes the form of a claw. When something similar happens in other parts of the body – cheek, stomach, arm – it is called panniculitis. The tissues seem to fasten to the underlying connective tissue leaving an impression, like a dimple. Along with arthritis, there might be acute synovitis with subsequent inflammation of the tendons. But the most common feature of iron overload is chondrocalcinosis also known as pseudo-gout. Arthritis is one of the most difficult symptoms to improve. Furthermore, iron promotes the growth of microorganisms, which can further contribute to the inflammation associated with arthritis.
Upper Respiratory
Copper unbound, pneumonia due to copper deficiency
Root Canal
A CLASSIC “Chronic Fe-AR” that MANY clients have is unresolved (root canals) & disruptive procedures (Hg removal), etc at the hands of their well-intentioned, but mineral depleting dentists!... As Hal Huggins, DDS declared in his famous book “It’s ALL in Your Head!” except he was noting that ~80% of peoples PHYSICAL problems FOLLOWED a visit to the Dentist!!! A frightening statistic! Dental procedures, as you & your “Drill-less” DDS Dad KNOW, are a MAJOR source of Mineral Dyshomeostasis— but now we have an even DEEPER appreciation for their metabolic impact! Please listen to this. Please stop your dentists from doing this procedure. The root canal tooth is simply a cause of chronic infection. Each one releases an average of 25 anaerobic bacteria from its bloodless dentin tubules into our bloodstream continuously. These same bacteria end up in our microscopic capillaries, tendons or ligaments, fascia, and arterial walls where they cause chronic infections. This is a major cause of disease. Nearly all cancer, neurologic disease, heart disease and chronic illness is related to infection and iron levels. If there is high iron in the body, this will all be more rapid, more severe, and more deadly. Iron cannot be measured accurately in the human due to Amyloid protein. Amyloid is a major storage protein for iron. We can only estimate the levels of iron predicted by water and food-related absorption. There may be no procedure than Root Canals in the human that could be more harmful to our health. Who told us? Why are we not informed? This is published information, obviously. We have a problem. Please never allow it. Ask your dentist to get an ozone generator for the DUWL. All other water units are contaminated. Published also. Good care is needed. Insurance may not pay to get rid of an infected toxic root canal tooth and replacement with an implant. Insurance companies may pay for the deadly root canal procedure. Think about it. Sorry. Blessings, Robert Thompson, M.D.
SCAD Spontaneous Coronary Artery Dissection
Appears to be akin to an aneurism, which is a breakdown of the integrity of the arterial wall CAUSED by Copper toxicity (too little proper Copper & too much unbound Copper...), which is key to Collagen formation. How does this happen? In a Mg deficient body, there is an exaggerated response to "Stressors!" Adrenals get fatigued. Fatigued Adrenals are a MAGNET for Copper (Ann-Louise Gittleson, PhD). And why is this happening? Because fatigued Adrenals can't generate energy (Mg-ATP), which is essential to bind Copper to Ceruloplasmin... Again, all roads lead back to minerals & esp. to Maggie.
Scoliosis
A sign of copper dysregulation, maybe even deficiency. wife has been doing chiropractor for 38 years. She has healed dozens of clients of scoliosis with just chiropractic alone because she knows that the issue, it's a signaling issue as well. There's many ways to solve this problems. I'm sure there are acupunctures who've solved scoliosis with acupuncture. Again, as a mineralist, what I'm looking for is how do we ensure proper signaling and proper energy production, and a body that's under stress is going to begin to create curvature of the spine or flat feet because certain enzymes aren't being fed properly. There's just different pathways of explaining what the dynamic is.
Seizure
* Possible adverse effects of stimulant drugs on individuals with low magnesium reserves may include seizures,(RickMalter) Magnesium deficiency has been linked to even more deleterious effects such as convulsions, seizures, tetany and epilepsy(TraceElements70) Sodium deficiency or hyponatriemia can cause symptoms of headaches, confusion, seizures and coma..(TraceElements150) The effects of lead on the nervous system have implicated it as a major contributor to hyperactivity, learning disabilities, behavioral disorders, attention deficit, seizures and decreased IQ. Reports have implicated lead in the Sudden Infant Death Syndrome (SIDS). It was found that the incidence of SIDS followed increased air levels of lead by one or two months. Tissue studies of infants who died of SIDS revealed higher lead concentrations than those who died of other causes. Lead displaces calcium and is deposited in bone through the ends or joints. Lead can destroy the normal cartilage tissue and contribute to arthritis. Since the teeth are similar to bone, lead exposure can increase the formation of dental caries in children.(TraceElements158) In this narrative review we focus on acute symptomatic seizures occurring in subjects with electrolyte disturbances. Quite surprisingly, despite its clinical relevance, this issue has received very little attention in the scientific literature. Electrolyte abnormalities are commonly encoun- tered in clinical daily practice, and their diagnosis relies on routine laboratory findings. Acute and severe electrolyte imbalances can manifest with seizures, which may be the sole present- ing symptom. Seizures are more frequently observed in patients with sodium disorders (es- pecially hyponatremia), hypocalcemia, and hypomagnesemia. They do not entail a diagnosis of epilepsy, but are classified as acute symptomatic seizures. EEG has little specificity in dif- ferentiating between various electrolyte disturbances. The prominent EEG feature is slowing of the normal background activity, although other EEG findings, including various epilepti- form abnormalities may occur. An accurate and prompt diagnosis should be established for a successful management of seizures, as rapid identification and correction of the underlying electrolyte disturbance (rather than an antiepileptic treatment) are of crucial importance in the control of seizures and prevention of permanent brain damage. Key WordszzEEG, electrolyte, epilepsy, seizures, hyponatremia, hypernatremia, hypocalcemia. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712283/pdf/jcn-12-21.pdf Blocking potassium channel in mice brains causes seizures https://www.bcm.edu/news/brain/blocking-potassium-channel-causes-seizures?fbclid=IwAR2MTwOngSr5yXVqxpKqzuEDeVvwTj123VdqpoyJ1UKxezpBjw7KZuCNouQ Let’s ALL understand that “K+ Channels” are Voltage-gated, which run on the battery of Mg-ATP: https://www.ncbi.nlm.nih.gov/m/pubmed/1724332/ I’ll let YOU ALL guess what dark, Toxic Heavy Metal BUMPS Maggie... The plot thickens... Mg-ATP is NOT the sole ATP battery: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874693/ I STILL think “Rusty” is the culprit!... Cheers! The role of ATP-sensitive potassium channels in cellular function and protection in the cardiovascular system https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874693/?fbclid=IwAR3Oc9LaNAzozpUHA9imNU7WbUo7ZnKXCmxBqlyWNb04MWBsuWvphJkQ4do The role of ATP-sensitive… Ca2+ and Mg-ATP activated potassium channels from rat pulmonary artery. Robertson BE, et al. Pflugers Arch. 1992. Show full citation Abstract We have observed a novel class of calcium-activated potassium channel which is activated by physiological levels of intracellular ATP. These KCa,ATP channels are found on smooth muscle cells isolated from the pulmonary artery. Since their activation by ATP is Mg2+ dependent and is poorly evoked by non- or slowly-hydrolyzed ATP analogues, we conclude that it involves phosphorylation. We suggest that in hypoxia a reduction of intracellular ATP may reduce KCa,ATP channel activity and thereby tend to depolarize the cells. This effect would increase Ca2+ entry through voltage-activated Ca2+ channels and contribute to vasoconstriction. https://www.ncbi.nlm.nih.gov/m/pubmed/1528724/?fbclid=IwAR3PmCFPYIdeVaM5LMW5eku1PLuCHFCkiX5YpcamImv_g6TyAX2qj11E3WQ ************* A “new” Potassium channel that involves Ca++ & H+ (which implies it’s pH driven!) http://jcb.rupress.org/.../2017/05/15/jcb.201704017.full.pdf Please NOTE: o You CAN’T talk about Ca++ w/o understanding Mg++ Status... o You CAN’T talk about pH changes w/o considering Iron’s acid-driving impact on Cellular pH... o You CAN’T seriously discuss Ca++ Status w/o considering Iron’s impact on MPC-1, TRP-1, ER Stress (that Floods Ca++ into cell...), stellate Cells, etc. The challenge is that far TOO MANY Research studies IGNORE Mg++ & Fe++. And these are the TWO Minerals that “fight” ALL DAY LONG, & when Iron wins the fight — BECAUSE FERROXIDASE IS MIA — Calcium, the mineral of cement, gets laid down... And too much Calcium, coupled w/ too little Maggie CAUSES Potassium LOSS that results in seizures... The Article ^^^^ refers to TRMPL-1 Channels... TRMPL-1 Channels are “Iron Release” Channels in Lysosomes: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301259/ It’s appalling how poorly trained or completely un-curious these “ologists” are these days... Dysregulation of Iron CAUSES Seizures. Period! Q.E.D. The Type IV Mucolipidosis-Associated Protein TRPML1 is an Endo-lysosomal Iron Release Channel https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301259/?fbclid=IwAR1YCVmx2983wt8Drxcazy5owhKt6n_ux63KPDzwtj93VyxOgVNEjvTotcE Mg-ATP is involved to make them all work. It means to re-activate the "blocked" channels one should have more Mg and less Fe. Then more Potassium will flood into the cells, right? http://www.jbc.org/content/early/2017/03/30/jbc.M116.772160.full.pdf?fbclid=IwAR1kUpEa966uNq10F914pUFOUqtZMtD1HdourN21RP0f1pvnTwQoARPOGdM
SIBO
BACTERIAL OVERGROWTH feeding on iron especially in the small intestine. Iron from food needs to go from ferrous to ferric and ferroxidase enzyme. Stressed out and exposed to known agents for copper Dysregulation - ferroxidase goes south and the iron can’t get out of the enterocyctes. BECOMES attractive platform for bacterial overgrowth.
Sleep Apnea
Let's be CLEAR folks, BOTH "Tongue Tie" and "Sleep APNEA" are clinical signs of LOW Bioavailable Copper, and therefore EXCESS, UNBOUND IRON... The former is a methylation issue -- Methionine Synthase and some 200 Methyltransferase enzymes REQUIRE Bioavailable Copper... The Latter issue has to do with faulty "Respiration" -- NOT in our Lungs, but in our Mitochondria. THAT ^^^^ Respiration is Cellular & REQUIRES Bioavailable Copper in Complex IV of the Mitochondria to "Activate" the O2 molecules into 2 H2O to then RELEASE the energy precursor: 3 molecules of ADP. That Complex IV clips along at a rate of 250 O2 molecules EVERY SECOND... If there's NOT enough Copper in that Complex IV, Cellular Respiration SLOOOOOWS down... THAT ^^^^ is "sleep apnea!" These are NOT "Medical Diseases..." They ARE, however, clinical signs of Metabolic Dysfunction CAUSED by Mineral Dysregulation. And NOTHING dysregulates the minerals faster than excess, unbound Iron... Please RE-READ these concepts, again, to let these metabolic TRUTHS sink in!
Sleep Issues
 Your body is a wonderland, seriously, of networks and systems. You’ve got nerves in every part of you, from the tips of your toes to the top of your head. Muscle fibers encase bones in a protective sheath, utilizing connective tissue at the joints allowing for maximum strength and flexibility. Hormones regulate your mood, sleep, appetite, and much more. Your respiratory system ensures enough life-giving breath makes it to your muscles, brain, and blood, to power you through each moment of the day. Circulation keeps everything moving, and your lymphatic system flushes away what’s not working for you anymore. You are a well-oiled machine and a miracle of science and nature, believe that. One key way to get the most out of life as a human being is really to take all of this to heart. The very nature of your body is balance. Every part of you works in harmony with every other part of you, to ensure a well-rested, pain-free, happy, healthy you. If that’s not happening for you, there’s an area of imbalance somewhere. You’ll want to get at the root of it as quickly as you can. Traditional Chinese Medicine (TCM) has what’s known as an “organ clock”, which is essentially a handy guide to the time of day each organ is functioning at its peak level and expending the most energy. (1) So if your disturbed sleep is wearing you out, take heart. Using the TCM organ clock, we’ve isolated some areas you might want to investigate, based on when you’re waking up at night. 10 pm- 11 pm: Hormones and Metabolism Stressed out? Bad day at work? Did you just NOW think of the perfect comeback for that snarky comment from your coworker earlier? Sounds like you’re having trouble falling asleep in the first place. The best thing to do here is try to understand and fix the root causes of your stress. When you are constantly stressed out, your body is in a state of panic, basically. Fight or flight. Fighting gets the old adrenaline pumping. Fighting constantly, well that’s exhausting. Next stop, adrenal fatigue. Metabolism comes into play where sleep is concerned too. Studies have shown a connection between the quality of sleep and a higher BMI (Body Mass Index). What’s the connection? In short, poor sleep disrupts the body’s leptin levels. (2) Leptin is a protein that helps regulate how your body processes and stores food. Not enough leptin? What to do with all these calories? Store ‘em as fat! That’s your sleep-deprived bod talking. 11 pm- 1 am: Gallbladder Feeling resentful or indecisive? In Chinese medicine, the gallbladder and sleep are closely intertwined, and issues with the gallbladder often manifest as sleep problems. (3) On an anatomical level, the gallbladder secretes and stores bile, which is used to break down and digest food. It’s not as functional when you’re sleeping, because you’re not eating. But if you find yourself waking up just a few hours after falling asleep, it might be a sign that your gallbladder is working overtime, and it doesn’t need to. Bile is not something you want too much or too little of. Too much can be an irritant (hi, resentment), and too little will give you trouble digesting the food you ate. 1 am- 3 am: Liver Have you been irritable, frustrated, or angry? The connection between poor sleep and liver problems is a strong one, and folks who investigate their 1-3am sleep issues sometimes find their liver in need of rebalancing. On an emotional level, the liver is strongly connected to anger, which is interesting because physically it’s a filtering organ, meant to process toxins. Got toxins? You’re not alone, and there are a lot of ways you can detox your liver. Dandelion tea and some quality “me” time are two simple but effective ways. (4) 3-5am: Lungs In TCM, breath is life, and life is qi (pronounced: chi). Life is energy, life is the force moving through you. Your lungs have this very important job of breathing you, for moving the life force around you, nourishing every part of you. Has something sad, or tragic happened lately? Something that took your breath away? If you find yourself awake between 3 and 5 am, your lungs might be trying to recover. Wheezing and shortness of breath are two other obvious signs of imbalance. Understanding the root cause of any lung issues will go a long way in supporting every part of you that needs breath. (1) 5am-7am: Large Intestine On a physical level, the large intestine is responsible for processing and elimination of waste. On an emotional level, it’s all about “letting go”. This organ is most active between 5 and 7 am, so it’s likely no surprise it’s also a good time to have a bowel movement. If there’s an imbalance in this area, it will manifest as an inability to let go, either physically or emotionally. Constipation on the physical side, and depression, sadness, and even apathy on the emotional side, are indicators of an issue worth addressing here. (5) Good Night! Waking up at night – any time of night – is a disruption to your body’s normal rhythms and is no fun! Using the TCM organ clock is one way to pinpoint problems and correct them, but it’s also great to develop proper sleep hygiene practices in general. The CDC (Centers for Disease Control) recommends sticking to a regular bedtime schedule, a cool and dark sleeping environment, no big meals, caffeine, or alcohol before bed, and removing electronics from your sleeping environment too. (6) Now get some sleep, you 1. TCM Organ Clock, http://naturopathicbynature.com/traditional-chinese-medicine-organ-times/ 2. Leptin, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929498/ 3. Gallbladder, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414091/ 4. Liver, https://www.naturmend.com/blog/2013/04/09/the-connection-between-sleep-and-the-liver/ 5. Large Intestine, https://fiveseasonsmedicine.com/the-large-intestine-channel-letting-go-of-whats-not-needed/ 6. Sleep Hygiene, https://www.cdc.gov/sleep/about_sleep/sleep_hygiene.html
SRB
Phytic has been poorly represented: it’s a way to bind iron Couldn’t tell you exactly how its working, but it does. Phytic acid does chelate iron - electrochemically
Success of the RCP:
The GREAT temptation of this process to remineralize and rebalance the body is to expect that the HTMA Bars and Blood result numbers will ALL come back into "perfect" alignment... Truth be known, they are very slow to respond... But what invariably DOES change over the continued use of the RCP are the following 5 factors: o Sleep patterns become more restorative... o Appetite becomes more appropriate... o Waste removal becomes more regular... o Energy levels become more lasting & predictable... o Mood becomes more aligned with circumstances... These 5 factors ^^^^ are the "Habits of Healthy Living" that are indicative of metabolic balance... Many who engage with the RCP Protocol find improvements across ALL 5... But this process, just like MTHR NATURE, does take time. And most importantly, what these 5 factors ALSO represent is the enhanced ability to "metabolize Stress!" And isn't that what we ALL really need?!?
Sunlight
Sunlight has TWO Key Actions: o Sunlight stimulates the synthesis of Vitamin-D (but you've got to have Cholesterol and Magnesium in your diet, right?... o Sunlight ACTIVATES the breakdown of Retinol into the many different Retinoid factors that RUN OUR BODIES & OUR NUCLEII...
Synthetic methylated B vitamins
methylated B vitamins, well, those B vitamins are supposed to be activated by copper. Well, what are they doing to methylate them in the lab? They're not using copper. We don't know what they're using. The energy of whatever they're using is getting infused into those supplements, what they doing in the lab that is chemically the same, but it lacks the frequency and the biology of Mother Nature. how synthetic vitamins are made? As in coal tar and other petroleum products, hexane, formaldehyde, GMO corn, sugar, etc.
Synthetic Vitamin D Supplementation
o Vitamin D supplements destroy Vitamin A status o Vitamin A and D share a symbiotic relationship o Vitamin D supplements harms retinol status o Retinol is missing from our diet o Increased use of coconut oil, olive oil, avocado oils, sunflower oil, canola oil doesn’t have retinol so won’t help build retinol status o Animal fats are needed to build retinol status o Need minimum of 3,000IU daily of retinol o Low fat ensures low retinol status o Retinol is needed to make water soluble sulphate (cholesterol) from the sunshine to move cholesterol around the body like it should - when it doesn’t - uptick of LDL in bloods o Retinol ensures protection against skin damage (oxidative) from sun o Retinol is needed to load the Copper onto ceruloplasmin transport protein for iron and copper to move around our body to create energy o Low copper/ceruloplasmin ensures uptick of metabolic stress - adrenals, muscles, heart, liver, thyroid etc. o Retinol rich foods - CLO, grassed fed beef liver/heart, whole food C, chickens getting sunshine (eggs), grass fed butter from grassed fed cows etc. o Vit D needs retinol, magnesium to convert vitamin d to useable vitamin d o Disruption of copper and iron causes magnesium loss o Magnesium protects us from oxidative stress https://medical.veritashealthycommunity.com/resources/radio-talk-shows/ Vitamin D - supplementation and recovery from A typical recovery time? Four years. That's how long it takes for that metabolite to work its way out. Again, what people are taking is a soy-based nutrient. People don't really know what they're taking. Nobody really knows what's in that vitamin D supplement. I have grave concerns about it, but it is fat-soluble, and I think it is having devastating impact on peoples' bodies, and when potassium gets this low, there's two things that happen inside the cell. Iron can get in a lot easier, because the pH drops when potassium is that low, and the other thing that happens is hydrogen peroxide builds up inside the cell. Well hydrogen peroxide is more acidic, so it's just a wicked combination. So loosely translated, vitamin D supplements increase hydrogen peroxide. You know what hydrogen peroxide is called? It's called a bleaching agent. Women especially, and guys, have used that over the years to bleach their hair. Take the color out of their hair. Well there's a whole bunch of proteins in our body that need to have color in them because they resonate with different frequencies of light. Well, when you have too much hydrogen peroxide, you're preventing the cell's ability to communicate with the light, so that's a big problem. 1) Increase your Magnesium I.Q.and the enzymes that it REGULATES, esp. those involving Hormone-D! (25(OH)ase, 1,25 (OH)2D3, Vit-D transport protein, etc.) Please STUDY Fig 1: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765911/ 2) Increase your intake of Sunshine, Cholesterol & Magnesium! 3) Focus on your Intake of REAL Vitamin-A (Retinol) that MUST be in proper balance with Vitamin-D... 4) IGNORE the insane isolationist focus that Vitamin-D, ALONE, "D"oes it all... That is PURE "D"eception and "D"isinformation... "A" votre sante! Hormone-D Articles on RCP website https://therootcauseprotocol.com/cate.../research/hormone-d/ https://therootcauseprotocol.com/iron-toxicity-post-50.../ Discussion around Sir Douglas Kell's research about iron and vitamin d... https://www.facebook.com/groups/MagnesiumAdvocacy/permalink/1666418960092833/?hc_location=ufi https://www.facebook.com/groups/388392151228860?view=permalink&id=1988371124564280 Magnesium, vitamin D status and mortality: results from US National… NCBI.NLM.NIH.GOV https://www.facebook.com/groups/MagnesiumAdvocacy/permalink/1714029791998416/ VITAMIN/HORMONE D INFORMATION: From time to time (haha!!) we get asked for guidance about raising vitamin D. What has been taught in this group for many years is how the Vitamin D (aka 'Hormone D') tests that physicians often opt for, doesn't give us a true view on what's happening in our bodies. Low Hormone D is giving us an indication that we are low in magnesium (which is needed for the conversion of the two types of Hormone D)... and beyond that, it's flagging that the mineral movement in the body isn't happening effectively. Looking at a snapshot of one hormone or vitamin isn't going to give us full context to what else is happening at the time. Summary of Morley's position on "D" http://my-magnesium.com/hormone-d.html Photo album dedicated to Hormone D references: https://www.facebook.com/media/set/... The full "four panel" items to be tested to understand where Hormone D is actually positioned: http://requestatest.com/mag-vitamin-d-panel--testing (Don't forget though, the "Full Monty" panel is going to give much more insight into your health as a whole) There are a MASSIVE quantity of references on the gotmag website too... http://gotmag.org/category/hormone-d/ Home Here’s another useful reference. There is no clinical benefit to Vitamin D over 21. (Those in Australia and some other countries should note our units are different, so it is more than 21 for us) For an explanation, see... http://www.medicalnewstoday.com/articles/260147.php "However, excessive vitamin D levels may be bad for you - any vitamin D levels above 21 nanograms per milliliter were found to be linked to an increase in CRP, which is associated with the hardening of blood vessels and a greater risk of developing cardiovascular problems. The team has also found a link between excess vitamin D and raised levels of homocysteine, which can increase the risk of cardiovascular diseases." This is a great group if you want to dig deeper into understanding Vitamin D. Jim, who runs the group, is also in this group and understands much on the interaction of D with the other minerals beyond just D. https://www.facebook.com/groups/517807781731760/ Jim Stephenson Jr. on D: Most of the literature shows a lack of benefit from it. Other shows the goal is too high. Then there are papers about how it’s not running around in serum. There are only a few papers limited to damage by it and it was an unexpected result. Like falls increasing in the postmenopausal woman taking it. I’ll post a few things below here. These are three reverse J shaped curves of all cause mortality. At least the middle one is non US unit of measure. For perspective. 50 nmol/liter = 20 ng/ml 60 nmol/liter = 24 ng/ml These are about too high of a goal. https://www.ncbi.nlm.nih.gov/m/pubmed/22573406/ https://academic.oup.com/jcem/article/100/6/2339/2829632 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701270/... Three papers about no benefit over 21. https://www.ncbi.nlm.nih.gov/m/pubmed/21996139/ https://www.ncbi.nlm.nih.gov/m/pubmed/24276459/ https://www.ncbi.nlm.nih.gov/m/pubmed/23601272/ This shows why serum isn’t the ONLY D you have. Serum isn’t storage. C. Hepatic 25-Hydroxylation "Vitamin D does not circulate for long in the bloodstream but, instead, is immediately taken up by adipose tissue for storage or liver for further metabolism. In humans, tissue storage of vitamin D can last for months or even years." https://www.physiology.org/.../10.../physrev.1998.78.4.1193 The potential danger of taking D3 and measuring 25D. Pretty important message here: "Hypercalcemia state continues for several months when D2 or D3 are responsible for the toxicity whereas the hypercalcemia would subside in a week when 1 alpha(OH) D3 or 1,25 (OH)2D3 are responsible for the toxicity." http://www.ncbi.nlm.nih.gov/pubmed/8483281 Many older adults should avoid taking vitamin D and calcium supplements to prevent falls and fractures, and focus instead on exercises to improve balance and coordination, U.S. doctors recommend. The conclusion issued Tuesday by the U.S. Preventive Services Task Force (USPSTF) on fall and fracture prevention comes amid growing debate in the medical community over the role of vitamin D, which may help some people at lower doses but is linked to an increased risk of fractures, falls, kidney stones and certain cancers at higher doses. https://www.nbcnews.com/.../older-adults-may-not-need... I gave the hormone imprinting papers also. That’s more relevant to children though. It’s important to not lose sight of the fact that the body decides what to make AND the body makes many molecules, not JUST D3. There’s no way to take the other molecules the body makes. Think about that. Or feedbacks to prevent the over production of D. I’m against taking pills of vitamin D. I want to make it perfectly clear why that’s not a sound practice. This is chasing a number. The serum level of 25D, typically 30 or above to satisfy mainstream. If you don’t have that you will be advised to take D3. Notice, this is a different form of D. You will likely take a lot of it but you will never have it measured. There’s no test for that. (Don’t be silly by making sense). They will continue to measure 25D. What it MAY become and where they may by chance, find it (serum-it’s a fat soluble vitamin made for storage. Think of a hibernating bear). I said may become. Here’s why. It can stay D3 and hang in serum. Untested. It can get stored in fat, as D3. Untested. It can become 20OHD, the sun protection analogue. Untested. It can become 24,25S/R. One is the bone healer. Untested. It can become 25D, STORED IN FAT. UNTESTED. It can become Epi-3 25D. D formed from another pathway, epimerization. There are at least 3. Hydrolation and lactonization being two others. Hydrolation is the one 25D is from. Some of these analogues can “cross over” into another pathway. What is the take home message? The body decides what to make. Not the Vitamin D Council Psychiatrist Cannel. Specific document on how Vit D supplementation decreases or affects magnesium levels? This is what the doc wants to see. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854088/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539504/ If you search Secosteroid Hormone D for the word magnesium there’s tons more there. I recently put several pieces into one piece. I’ll share it here. It’s on my personal page as well and can be shared from there. Diagram of a SCAM. The Serum 25D level OBSESSION. (“Vitamin D”) I can explain the high level focus. They took everyone’s 25D level. They broke them out and grouped them by disease/condition. Then they did something very unscientific and everyone fell for it. They said their D level was the cause of their disease/condition. Turned correlation into causation. A HUGE NO NO in science. But remember, it’s been called a vitamin for generations. The thought of Rickets makes ppl tremble. And it was two genetic mutations OR a pure lack of sun. And to be quite honest we my still not have discovered the molecule that fixes that. Think about it. It could be made by the sun and remain undiscovered. It may get transferred to food sources, as well. No one is looking. It could be one of the molecules I mention but remain an action not recognized or attributed to that molecule. Like 20OHD. The D molecule we make in the sun that protects us from the sun. Or 5,6 trans-vitamin D. I cannot stress enough that NO ONE is looking. Where would that money come from??? The only reason anyone is studying D is to: 1)Make a synthetic. There are thousands of synthetic analogues. Some as simple as D5 2) Looking to piggyback their drug on the D delivery system. Serves about 33 tissue types. Great rail line. You notice the Combrio (spelling) high dose isn’t a trial. Why not? It’s not like we don’t need them. It’s really a calcium avoidance diet with tons of D so you don’t rodenticide yourself. The lesions going away are the proof. And self reporting. The lesions wax and wane in the absence of D. It’s the placebo effect. It takes 7 days for D3 to become 25D. It can become 1,25D as needed after that. But folks are always telling me how great they feel when they take it. But way too soon. 🤔🤔🤔 So the number that has become the target these days is way up there. Above any groupings of ANY ill ppl. It’s ludicrous. The folks not converting any 25D to 1,25 D in something known as the IMMUNE RESPONSE. This study is a HUGE wake up call. The reason everyone missed it is because they didn't use the same measurements. The study used nmol/liter, whereas most in the US are familiar with ng/ml. "Vitamin D insufficiency (25-hydroxyvitamin D [25(OH)D] < 50 nmol/liter) is prevalent (1–3) and has been suggested to be involved in various diseases such as diabetes, cardiovascular disease, depression, immune system diseases, and certain cancers (4–8). The biomarker used for the determination of vitamin D status is 25(OH)D, rather than the biologically active hormone 1,25-dihydroxyvitamin D (9)" But the RESULTS are shocking when you realize insufficiency level has the LOWEST MORTALITY. "All-cause mortality associated with serum 25(OH)D levels The association between all-cause mortality and serum levels of 25(OH)D was reverse J-shaped (Fig. 1A). A serum 25(OH)D level of 50–60 nmol/liter was associated with the lowest mortality risk. The hazard ratios [95% confidence intervals (CI)] of all-cause mortality at very low (10 nmol/liter) and high (140 nmol/liter) serum levels of 25(OH)D were 2.13 (2.02–2.24) and 1.42 (1.31–1.53), respectively. In subjects at least 60 yr old, the mortality was, as in the total population, lowest at a serum 25(OH)D level of 50–60 nmol/liter. In this age group, the hazard ratios (95% CI) of all-cause mortality at low (10 nmol/liter) and high (140 nmol/liter) serum levels of 25(OH)D were 2.04 (1.94–2.17) and 1.44 (1.32–1.56), respectively." For perspective. 50 nmol/liter = 20 ng/ml 60 nmol/liter = 24 ng/ml So LOWEST MORTALITY is at the bottom end of INSUFFICIENCY, one away from deficient. NOW THINK!!! The vitamin D Council now wants to go for 80 ng/ml. Many are on some wellness protocols going for 100ng/ml. INSANE!! Again, for perspective. 140 nmol/liter 56 ng/ml That above is what "high" is in the numbers most people are familiar with. That’s a lot if folks these days. https://academic.oup.com/.../doi/10.1210/jc.2012-1176... Careful with the unit of measure. The middle one uses non US units. https://www.ncbi.nlm.nih.gov/m/pubmed/22573406/ https://academic.oup.com/jcem/article/100/6/2339/2829632 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701270/... C. Hepatic 25-Hydroxylation "Vitamin D does not circulate for long in the bloodstream but, instead, is immediately taken up by adipose tissue for storage or liver for further metabolism. In humans, tissue storage of vitamin D can last for months or even years." In conclusion, from this cohort of asymptomatic adults, independent of traditional cardiovascular risk factors, we observed a statistically significant inverse relation between 25(OH)D at levels
Synthetic Vitamin D Supplementation
Synthetic Zinc Supplementation
Any zinc supplements blocks copper. Get zinc from foods. Supplemental zinc is tanking her ceruloplasmin ferroxidase function and depleting copper, which allows greater iron uptake/storage. It's the reason zinc supplements are not recommended. When zinc is low, we know unbound iron is high. We address the low zinc not by adding zinc but by removing iron.
Taurine
500mg to start, some with sensitivity to sulfates may feel sensation of feeling nausea and headache (very common.)
Teeth
Boron sets your teeth back into socket. Mom is mineralizing to brush with. Coconut oil pulling will remove toxic iron from the gums as will activated charcoal. Whole food C will stop bleeding gums. This is my experience.
Thyroid
>Does not run the body >Thyroids get weak when the adrenals get weak >Thyroperoxidase enzyme relies on bioavailable copper (vitamin c has copper at it’s core -tyrosine!) NOT! Ascorbic Acid >Healthiest when there are healthy levels of magnesium and healthy levels of bioavailable copper Morley on Thyroid We need to STOP this "Thyroid causes ALL Problems MADNESS!!!" CopperIron Dysregulation creates outrageous levels of Oxidative Stress that affect the metabolism of the Body & Brain & THAT then CAUSES: o Thyroid dysregulation, MOST OF WHICH occurs in the LIVER! o PCOS... o Hormone Dysregulation-- AGAIN occurring in the LIVER! o AND HUNDREDS OF OTHER AFFLICTIONS!... And unlike STTM, we REJECT: o Hormone-D! o Ascorbic Acid (it kills Ferroxidase!) o Iron Supplementation (that is metabolic POISON) o to name but a few points where we SEE the problem differently... I would encourage you to read up on the truth of Iron Toxicity noted in the 62 Posts on Iron Toxicity. And I would ALSO ask you -- and OTHERS -- to STOP pushing the beLIEf that the Thyroid runs the body... We KNOW better on the MAG FB Group! (From the RCPC Group) Catherine Julia Mort: Firstly, NDT is dessicated whole thyroid gland, usually from pigs and contains both T3 and T4. This is usually a better option than the synthetic variety. If someone has an autoimmune aspect to their thyroid underfunctioning, gluten free and getting away from nightshades really helps (personal testament). As the others have said, thyroid function usually improves on the RCP and meds’ can be reduced. ONLY under GP supervision. Other things to note: 1. T4 to T3 conversion happens mainly in the liver. If the liver is loaded with iron or not functioning properly this will reduce the conversion. Castor oil packs and donations are very helpful. 2. Selenium is also required and I know that UK and Australian souls are depleted. I have to supplement to maintain decent thyroid levels. 3. Also require zinc! So if iron is high, your zinc will be low. 4. Most of my hypothyroid clients and myself have very low potassium and very high calcium. We are stress cadets. Once adrenal function is restored then thyroid function follows. It is a marathon, but for me, liver, CLO, adrenal cocktails and EFT had a profound effect on my thyroid symptoms. STRESS is the biggest factor I have found personally, my thyroid ratio on the HTMA is crazy (around 400!) after stressful events. Thyroid hormone levels confirm this. EFT and happiness restore thyroid function 💖 💖 💖 💖 💖 I know bioavailable copper is a big player in thyroid hormone production... basically the RCP wins! Patrick Boyle: When your iron and copper are out of balance, you will have a thyroid issue. In part because iron is highly oxidative (STRESS) and will overwhelm your adrenals (responsible to controlling stress). In the case of Hashimoto's, it's a little more complex. If you look deeper for the root cause you will find that when the thyroid converts Iodide to Iodine by using H2O2, the body needs to break down the H2O2 back into water and oxygen when it's done. If this cannot happen, the hydrogen peroxide 'irritates' the thyroid gland tissues to a point it gets inflamed ("itis" means inflammation). Catalase is a copper dependent enzyme that converts H2O2 back to oxygen and water. If your ironcopper regulation is not balanced due to iron toxicity, low retinol, lack of bio-available copper etc... Catalase is not available to do it's job. As the thyroid gets inflamed, the body reacts by processes that actually bring iron to the damaged tissue (its part of your immune response). In Jym Moon's book (Iron: The Most Toxic Metal), he makes it very clear that iron has an affinity for and is drawn too, damaged tissue. If that iron isn't bound (controlled by bio-available copper bound to ceruloplasmin), the iron showing up is actually causing more problems because it's not behaving as it should. It's a bull in a china shop. As your body is activating your immune system to deal with the inflammation, it is also unwillingly being the cause of more inflammation. This is then labeled an 'autoimmune' disorder when in fact it's a copperiron dysregulation issue. You have to have your copper and ceruloplasmin working properly in order to make the iron in the body behave as nature intended it to. This is a simple and brief explanation without getting deep into some of the processes, enzymatic functions and chemical breakdowns. BTW, the reason doctors give you the thyroid meds and your antibodies go back down is that you are basically stopping the thyroid from doing it's job and the "itis" starts to calm down as a result of being on vacation. o "Stress!" CAUSES mineral loss, esp. to Mg & Zinc. o The Thyroid is RULED by the mineral ratio of Calcium/Potassium o The Adrenals are RULED by the mineral ratio of Sodium/Magnesium o It's well documented on STTM that ALL Thyroid issues FOLLOW Adrenal collapse... o When "Stress!" builds, and becomes CHRONIC, it creates mineral gyrations/chaos: - Mg goes down, which CAUSES Sodium to rise, eventually to fall, and Adrenals to get taxed as the Na/Mg ratio then gets smaller and smaller... - Mg goes down and Calcium rises & Potassium drops, too, which CAUSES the Thyroid ratio to go sky high and the Thyroid to slooooooow down... - Zinc goes down, and Copper builds which is stored in the Liver and is the BIGGEST cause of T4>>T3 disruption, which occurs there, and NOT in the Thyroid... o And yes, it's NOT conventional thinking, and yes, Hormones are involved, but it takes MINERALS to make them... Our bodies are designed to MAKE Hormones and NOT eat them... So, I hope that this makes some degree of sense given the unique focus of MAG and this gaggle of MAG-pies... I'm of the opinion that a large swath of the metabolic dysfunction that pervades the world is because we have been trained to RUSH to "treat" a Thyroid that is actually suffering from undernourished Adrenals that ONLY recover when Minerals, plenty of FAT, Sleep, wholefood Vit-C Complex (NOT Ascorbic Acid) and B-vitamins are restored... I realize that this is not "mainstream" thinking, but the fact that 1/3 of Americans (I don't know the # worldwide...) being on Synthroid and the level of obesity ONLY continues to accelerate, tells me that convention ain't working... As Einstein cautioned us, it's time for some fresh thinking when the problems don't go away... And here's a thoughtful essay written by Drs.David & Michael Wells that will shatter many myths about what "thyroid disease" really is... http://www.drwells.net/nutrition/topics/Hypothyroid.htm A votre sante! https://www.facebook.com/groups/MagnesiumAdvocacy/permalink/690212151046857/?comment_id= 690569927677746&offset=0&total_comments=56
Tongue-tie
It's incomplete development of the infant. That's a copper issue as well. Let's be CLEAR folks, BOTH "Tongue Tie" and "Sleep APNEA" are clinical signs of LOW Bioavailable Copper, and therefore EXCESS, UNBOUND IRON... The former is a methylation issue -- Methionine Synthase and some 200 Methyltransferase enzymes REQUIRE Bioavailable Copper... The Latter issue has to do with faulty "Respiration" -- NOT in our Lungs, but in our Mitochondria. THAT ^^^^ Respiration is Cellular & REQUIRES Bioavailable Copper in Complex IV of the Mitochondria to "Activate" the O2 molecules into 2 H2O to then RELEASE the energy precursor: 3 molecules of ADP. That Complex IV clips along at a rate of 250 O2 molecules EVERY SECOND... If there's NOT enough Copper in that Complex IV, Cellular Respiration SLOOOOOWS down... THAT ^^^^ is "sleep apnea!" These are NOT "Medical Diseases..." They ARE, however, clinical signs of Metabolic Dysfunction CAUSED by Mineral Dysregulation. And NOTHING dysregulates the minerals faster than excess, unbound Iron... Please RE-READ these concepts, again, to let these metabolic TRUTHS sink in!
Tourettes Syndrome
Morley Robbins: At the CORE of Tourette's Syndrome is CopperIron dysregulation. Please read: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936959/ Mg will help calm this neurological "fire," but the ORIGIN of this syndrome & neuroinflammation is a LACK of bioavailable Copper, aka Ceruloplasmin (Cp), COUPLE WITH EXCESS, Unbound Iron that CREATES Oxidative Stress for sport. https://www.facebook.com/groups/MagnesiumAdvocacy/permalink/1224775904257143/?%20comment_id=1224787944255939&comment_tracking=%7B%22tn%22%3A%22R%22%7D
Tranferrin
Transferrin is the main protein in the blood that binds to iron and transports it throughout the body. Transferrin levels rise with iron deficiency and fall in cases of iron overload. Transferrin is also responsible for circadian variation in serum iron (which peaks in the AM). Normally, iron is absorbed from food and transported throughout the body by transferrin, which is produced by the liver. About 70% of the iron is transported to the bone marrow and incorporated into hemoglobin within red blood cells. The remainder is stored in the tissues as ferritin.
Ulcerative Colitis
ulcerative colitis d/t lack of ceruloplasmin
Vegan/Vegetarian
This group does not advocate for fully plant based diets because there is no retinol (Vitamin A) in plants, nor is there sufficient levels of B12 in plants either. The diet recommended for all is an ancestral diet. Eat how your ancestors ate. There has never been a civilization in the history of this planet that has been vegan or vegetarian. Morley Robbins: When folks engage in a Veg-Diet, this is what happens: o Intake of Zinc drops... o Intake of Animal-based FATS (esp. Retinol) plummets... o Intake of Copper rises, largely due to the lack of Zinc... o And because there is a vacuous presence of Ceruloplasmin (Cp) -- which FEW practitioners are trained to look for -- the Copper is too unbound to be functional because the Liver MUST have Retinol & other KEY nutrients to make Cp... o BUT LURKING IN THE SHADOWS, is the FACT that there is RAGING Iron dysregulation -- because the Ceruloplasmin is LOW & unbound Copper is HIGH -- and NO ONE THINKS to look for &/or assess the KNOWN metal -- IRON -- that CAUSES Oxidative & Nitosative Stress that is ACTUALLY CAUSING ALL THE CHAOS noted in your research... Again, sorry to be a wet dishrag, but there IS a hierarchy to these minerals, and the GREATEST tension is between Mg & Fe and they fight over Oxygen ALL DAY LONG. MAGpie question: Are there any vegetarian alternatives for the liver? Also are there any food options to get taurine? Ruth Lanton: Liver provides bio-available copper and iron in the right ratios, along with retinol (vitamin A) and B vitamins, including B-12. Retinol and B-12 can only be found in animal products, but that does includes eggs and dairy products. Neither of these are as rich a source as liver, but these ovo-lacto vegetarian foods do provide these nutrients to some degree. Beta-carotene is not retinol. Under optimal conditions, the body can convert beta-carotene into retinol, but not every body is efficient with that conversion. There are many sources for B vitamins other than B-12: leafy greens, whole grains, nuts, beans, bee pollen, and nutritional yeast. The only way to get B-12 on a vegan diet is from the synthetic version ("fortified" foods or B-12 supplements.) Neither of these are part of the RCP. Kristan Kershaw Consuming beef liver in capsule form is the path that many choose to go down. The simple answer is, there is no plant based source of retinol. Beta carotene is not retinol - so one can eat all the betacarotene they want, but if they haven’t the mag and active enzyme pathways to convert (enzymes needing bioavailable copper, for which pretty much all of us, vegetarian or meat eaters alike don’t have enough of, care of many reasons including excess iron).... then they won’t be doing the 12 steps needed to make retinol. Retinol is needed for ceruloplasmin creation in the body (which helps us with bioavailable copper).
Virus
viruses erupt when the body is under stress... stress causes iron to trigger metallothionein 1,000x more than binding of bioavailable copper 1,000x by zinc.
Vitamin A: Retinol
Morley has said: We know that iron can be 10x higher in the tissues than in the blood and on the same inference vitamin A retinol can be 10x higher in the blood than in the tissues.
Vitamin A:Vitamin D
Magnesium is a cofactor to increasing Vitamin D. Any type of magnesium will work. The other cofactors are retinol (Vitamin A), boron, and Vitamin K2. We get retinol from the beef liver and cod liver oil. Boron comes from certain fruits like raisins and prunes, ionic mineral drops, or borax. K2 should come from dairy products of grass fed animals, eggs, and beef liver. The dynamic between retinol/retinoic acids (hormone form of retinol) and calcitriol (active form of calcidiol) - what do we find when we open the livers of cod? Ten x more Vit A than D The body is about fat and water soluble ratios, ☛ Underlying ratio to Cu: Fe dynamic….. ☛ Production of ROS to the antioxidant system (AOS) - almost all of which are activated by Cu, which are designed to neutralise the ROS. ☛ Best visual on the body is the bell-shaped curve. Book ends, things aren’t working, as we reach optimal, that’s optimum function. Invariably, there’s some shifts within the area near optimal. ☛ Important connection between eyes (retina’s use retinol) and connection to the liver. ☛ What does vitamin d do? Causes renal potassium wasting, and it causes iron to go into the tissue even deeper. ☛ Mononutrient insanity! Let’s talk about the Vit A: Vit D ratio? Let’s talk about the dynamics of ROS to the AOS? Let’s talk about the seesaw in the body which drives the bell shaped curve.
Vitamin C - Whole Food Vitamin C
Kristan Kershaw: Why Whole food C It is required to make Ceruloplasmin Ferroxidase (enzyme), which is required to regulate both copper and iron. The Whole food C molecule contains the tyrosinase enzyme with copper at its core and 95% of the whole food C is stored in the adrenals. The adrenals direct the liver to make Ceruloplasmin. Ceruloplasmin ferroxidase is required for making 200+ copper dependent enzymes, including: SOD, Catalase, Glutathione Peroxidase needed for our immune systems. Ceruloplasmin Ferroxidase enzyme is required for hundreds of functions in the body. Avoid ascorbic acid, ascorbates, citric acid, citrates which damage the copper/ceruloplasmin bond. On CITRATES found in food sources of Vitamin C. Ruth Lanton. ISOLATED citrates can mess up the body's balance. When it's found as part of a whole food, such as citrus fruits, it's already present with other factors that balance it out and make it safe for the body. It's similar to how ascorbic acid is unhealthy, but whole food vitamin C is fine, even though the full C molecule does contain ascorbic acid as the outside part of the molecule.
Vitamin K2
We don't recommend supplementing with Vitamin K2... Here is an old post talking about k2 - https://www.facebook.com/groups/MagnesiumAdvocacy/permalink/1649157435152319/ (Here I read that Vit D should always be taken with Vit K2, so Rosita CLO with naturally occurring Vit D needs to be taken with Vit K2 MK7. How come Vit K2 isn't being recommended in this group? Can any RCPC comment on this please? https://www.ondietandhealth.com/reasons-to-switch-to-rosit…/ https://www.ondietandhealth.com/produ…/rosita-cod-liver-oil/)
Weight Loss
Adipose tissue stores of vitamin D probably represent “non-specific” stores sequestered because of the hydrophobic nature of vitamin D, but the extent to which the processes of accumulation or mobilization are regulated by normal physiological mechanisms remains unknown at this time. Rosenstreich et al. (1971) first identified adipose tissue as the primary site of vitamin D accumulation from experiments in which radiolabeled vitamin D was administered to vitamin D–deficient rats. Tissue levels of radioactivity measured during vitamin D repletion and during a subsequent period of deprivation showed that adipose tissue acquired the greatest quantity of radioactive compound and had the slowest rate of release. Work by Liel et al. (1988) suggested that there was enhanced uptake and clearance of vitamin D by adipose tissue in obese subjects compared with those of normal weights. Similarly, Wortsman et al. (2000) concluded that in obese subjects, vitamin D was stored in adipose tissue and not released when needed. Finally, Blum et al. (2008) found that, in elderly subjects supplemented with 700 IU of vitamin D per day, for every additional 15 kg of weight above “normal” at baseline, the mean adjusted change in 25OHD level was approximately 10 nmol/L lower after 1 year of supplementation. The authors estimated that in order for subjects with body mass indexes (BMIs) above the normal range to obtain an increase in serum 25OHD level similar to that of subjects with weight in the normal range, an additional 17 percent increase in vitamin D above the administered dose of 700 IU/day would be needed for every 10 kg increase in body weight above baseline in their study population. The implication of these studies is that vitamin D deposited in fat tissue is not readily available, and obese individuals may require larger than usual doses of vitamin D supplements to achieve a serum 25OHD level comparable to that of their normal weight counterparts. In support of the hypothesis that vitamin D is stored in adipose tissues, weight reduction studies show that serum 25OHD levels rise when obese individuals lose body fat (Riedt et al., 2005; Zitterman et al., 2009; Tzotzas et al., 2010). Conclusive statements regarding changes in serum 25OHD levels after gastric bypass surgery cannot be made, as a result of confounding factors, such as weight change, possible malabsorption, and diet. There is evidence of a rise in serum 25OHD levels after surgery (Mahdy et al., 2008; Aasheim et al., 2009; Goldner et al., 2009; Bruno et al., 2010), as well as evidence that there is no change after surgery (Riedt et al., 2006; Fleischer et al., 2008; Valderas et al., 2009). Gehrer et al. (2010) indicated that serum 25OHD levels decrease after gastric bypass surgery, although the quality of the methods used is questionable. https://www.ncbi.nlm.nih.gov/books/NBK56061/
Weight gain on RCP
"Over a year ago I was not in the protocol. I was very skinny and with an iron infestation. I had candida. I have been in the protocol for a year. My candida is gone. I have gained a lot of weight. A lot of improvement specifically with memory. I think when I was skinny the iron was in my brain and other organs. I think it has moved out of my organs to my body fat. I believe eventually will be gone and I will lose some weight. However I don't want to be skinny again"......................... Yes, there is an aspect of REVERSING the Food System-driven LOADING UP OF IRON (because of the Fortification programs and LACK of Copper...) that we're still working on. There is a small subset of the RCP community that experiences this added weight, but not all... I have some theories WHY, but still working on that aspect of it. Our bodies are FIERCELY resistant to "letting go" of Iron. There is NO Hormonal Regulation of this metal, and as we're learning, there is ONE preferred mechanism for it's removal -- blood loss. The likely KEY variable in REVERSING this Iron Loading process is making sure that there's OPTIMAL levels & activity of Ceruloplasmin... (Which becomes a Catch-22, right?...) Thanks, again, for your remarks, your recovery, and your optimism for this future... "A" votre sante! Kristan Kershaw There are many reasons - I suspect many we will never know. One worth noting is that the body will shift iron into a cell called a macrophage - they become “iron laden macrophages” and then they have an affinity with fat cells. So, the body has these macrophages it needs to ‘put’ somewhere. They have an affinity with fat. Body goes into backup mode and stores them into fat until it has the vehicles (ceruloplasmin?) and mineral backup to shift it effectively. So...I’d be doing everything in your power to focus on healing the body, healing the mind (EFT) and NOT focusing on the weight for now. It’s part of the coping mechanism imo and the more you stress on it, the more counterproductive it’ll be with your mag burn rate and healing. they may be mobilizing iron but not having enough bioavailable copper to deal with the iron. Can they do a blood donation? What are they doing to deal with their stress (EFT wise)? The emotional stress of weight gain is likely not helping. What about liver? What about more whole food vitamin c? Eli KhanlariEli Not enough quality of sleep and stress has a lot to do with weight gain. If one has covered all other possibility there is a good chance of those been the reasons. If you suffering from too much cortisol which is the stress hormone than that would affect your sleep and holds on to your fat. Kristan KershawKristan Eli Khanlari yes, this connection is strong! Though the reasoning behind it is likely somewhat different to what you expect 🙂 The stress triggers loss of Magnesium first, and when sustained, the adrenals being in fight-flight also triggers the release of metallothionein. This is a powerful metal binder - it’ll actually bind to copper 1000x more than it does to zinc though, and it’ll end up resulting in a lot less bioavailable copper. Copper is required for effective metabolism, especially to access fat in the body, as well as to make ferroxidase - the copper and iron transporter protein (& master antioxidant!). We need mag plus this bioavailable copper (& b vitamins) to make ATP, so once we are not getting enough sleep and under stress, it changes how we can mobilise and access energy and antioxidants, so the body will have a harder time dealing with oxidative stress from excess unbound iron, and it’ll lock it away in fat via ‘iron laden macrophages’. When locked up in fat, the body is protected from the oxidative stress…. hello weight gain and retention.
Helpful links
DNRS information and Video links: https://1drv.ms/w/s!Akih-lU0EiNtpAcI0CixEcoOYDQf
Jill Paterson-Walton - https://www.waltonwellness.com
Hormone D (Vitamin D) FB post: https://www.facebook.com/groups/388392151228860?view=permalink&id=1988371124564280
Hormone D https://therootcauseprotocol.com/category/research/hormone-d/
MTHFR:https://www.facebook.com/groups/MagnesiumAdvocacy/permalink/2021831831218209/
Osteoporosis:https://therootcauseprotocol.com/?s=osteoporosis
Osteoporosis:https://www.facebook.com/groups/MagnesiumAdvocacy/permalink/1708813685853360/
https://therootcauseprotocol.com/faq-adrenal-cocktail-recipes/
https://therootcauseprotocol.com/all-resources/
https://therootcauseprotocol.com/category/research/iron-toxicity/
https://therootcauseprotocol.com/category/testimonials/
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Facia
Hi Fred, This, from Morley, "ALL Fascia is made with Lysyl Oxidase, which REQUIRES Bioavailable Copper for its function...
NMDR Pain Receptors REQUIRE Mg++ in the channel to PREVENT Calcium-induced Pain to be triggered...
ALL Mg-ATP being produced in the Mitochondria (Complex IV & V) REQUIRE Bioavailable Copper and Magnesium...
Excess, unbound Iron KILLS ALL THE ABOVE ^^^^!
And unrelenting chronic "Stress!" is the FASTEST way to
o LOSE Magnesium...
o MAKE Copper BioUNavailable...
o MAKE Iron MORE Toxic to our homeostasis...
Great article, thanks for posting!
Cheers!" retrieved from https://www.facebook.com/groups/MagnesiumAdvocacy/posts/1450092845058780
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