Sorry, the best answer is D. According to the new IANS guidelines, acceptable anal cancer screening tools (beyond digital anorectal exam) are: anal cytology alone, anal high-risk HPV testing alone, anal cytology/hrHPV co-testing, anal cytology with hrHPV triage or anal hrHPV testing with cytology triage. The tools depend on a variety of local factors including HRA capacity, and availability of hrHPV testing.