Making It Stick: Considerations and Case Studies for Implementation of Long-Acting Antiretroviral Therapy (Web)

  • Making It Stick: Considerations and Case Studies for Implementation of Long-Acting Antiretroviral Therapy (Web)

  • Assessment

    Please answer the following questions based on what you learned in this activity.
  • 1. Which of the following individuals living with HIV do guidelines currently support initiating long-acting injectable cabotegravir/rilpivirine?*

  • Congratulations. The best choice is D. Answer A is not correct because LAI CAB/RPV is not currently recommended for use in pregnant individuals. Answer B is not correct because LAI CAB/RPV is not recommended in individuals with gluteal implants. Answer C is not correct because LAI CAB/RPV is not recommended in individuals with known resistance to the rilpivirine component.

    References:  https://clinicalinfo.hiv.gov/sites/default/files/guidelines/documents/adult-adolescent-arv/guidelines-adult-adolescent-arv.pdf

  • Sorry, the correct answer is D. Answer A is not correct because LAI CAB/RPV is not currently recommended for use in pregnant individuals. Answer B is not correct because LAI CAB/RPV is not recommended in individuals with gluteal implants. Answer C is not correct because LAI CAB/RPV is not recommended in individuals with known resistance to the rilpivirine component.

    References:  https://clinicalinfo.hiv.gov/sites/default/files/guidelines/documents/adult-adolescent-arv/guidelines-adult-adolescent-arv.pdf

  • 2. Based on real-world data, what is the most common reason forusing the LAI combination of cabotegravir plus lenacapavir?*

  • Congratulations. The best answer is C.  According to the reference, A is incorrect because 47% of individuals switching to this regimen had viremia at baseline (Viral suppression doubled to 94% with the use of CAB + LEN). While depressive disorders in choice B is described as a Warning and Precaution in the package labeling for Cabenuva, it is more specifically associated with the rilpivirine component. This reason is not listed as any justification for using this LAI combination of CAB + LEN. D is incorrect because only 1 patient in the reference was switched to this CAB/LEN due to high BMI.

    Reference: Gandhi M, et al. OFID, 2024

    https://academic.oup.com/ofid/article/11/4/ofae125/7646382   doi: 10.1093/ofid/ofae125

  • Sorry, the best answer is C. According to the reference, A is incorrect because 47% of individuals switching to this regimen had viremia at baseline (Viral suppression doubled to 94% with the use of CAB + LEN). While depressive disorders in choice B is described as a Warning and Precaution in the package labeling for Cabenuva, it is more specifically associated with the rilpivirine component. This reason is not listed as any justification for using this LAI combination of CAB + LEN. D is incorrect because only 1 patient in the reference was switched to this CAB/LEN due to high BMI.

    Reference: Gandhi M, et al. OFID, 2024

    https://academic.oup.com/ofid/article/11/4/ofae125/7646382   doi: 10.1093/ofid/ofae125

     

  • 3. You currently work in a very busy urban clinic providing care to persons with HIV. You have a dedicated, expert, but small interdisciplinary team of providers consisting of physicians, nurse practitioners, physician associates, registered nurses, clinical pharmacists, medical assistants, and social workers. You have limited resources and lack control over the clinic scheduling or staffing. You would like to implement long-acting injectable ART into the practice to provide your patients access to these new therapies. Based on this information alone, which of the following is the BEST initial strategy that you could use to support implementing LAI ART in your clinic?*

  • Congratulations. The best answer is A. Based on article by T McCrimmon, this suggestion was included as a qualitative potential implementation strategy to address organizational barriers to the widespread access and uptake of LAI. Answers B, C, D are less correct in that they require interventions or strategies that may be beyond the control of the person implementing LAI based on info provided in the case.

    Reference: McCrimmon T et al. AIDS Patient Care and STDs. 2024
    https://pubmed.ncbi.nlm.nih.gov/38381949/

  • Sorry, the best answer is A. Based on article by T McCrimmon, this suggestion was included as a qualitative potential implementation strategy to address organizational barriers to the widespread access and uptake of LAI. Answers B, C, D are less correct in that they require interventions or strategies that may be beyond the control of the person implementing LAI based on info provided in the case.

    Reference: McCrimmon T et al. AIDS Patient Care and STDs. 2024
    https://pubmed.ncbi.nlm.nih.gov/38381949/

  • Evaluation

    To receive your CME/CE credit for participating in this activity, please complete the following evaluation.
  • After participating in the webinar, please rate your current confidence implementing long-acting injectable ART.*
  • Did your confidence improve?
  • Rows
  • Rows
  • What barrier(s) impact your ability to make the change(s) you indicated above in your practice or with your care team? (check all that apply)*
  • Rows
  • Rows

  • Please provide the following informaiton to receive your CME/CE Certificate.


  •

  • The certificate emails auto-generated by this form are blocked by comcast.net email addresses. Please use an alternate email address if possible, or contact CEServices@academycme.org after submitting your form. **

  • Profession*
  • Please indicate your practice setting:*
  • Please select your area of practice:*
  • Number of years caring for people with HIV:*
  • On average, how many PWH do you see/impact per week?*
  • Amount of Time Spent in Activity/Number of Credits Claimed*

  • This educational activity was certified for a maximum of 1.0 AMA PRA Category 1 Credits(TM), 1.0 ANCC Contact Hours, 1.0 AAPA Category 1 CME credits, and 1.0 ACPE Contact Hours.

  • 1.25

  • 1.0

  • 0.75

  • 0.5

  • 0.25

  • Should be Empty: